Enzymes that hydrolyze adenine nucleotides in platelets and polymorphisms in the α2 gene of integrin α2β1 in patients with von Willebrand disease

Molecular and Cellular Biochemistry

Volumn 340, Issue 1-2, 2010, Pages 249-256

  Santos, Karen Freitas ^a   Battisti, Vanessa ^a   De Carvalho Corrêa, Maísa ^a   Mann, Thaís Rapachi ^a   Da Silva Pereira, Renata ^a   Do Carmo Araújo, Maria ^a   Brülê, Alice Odete ^a   Schetinger, Maria Rosa Chitolina ^a   Morsch, Vera Maria ^a  

^a FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

Author keywords

2 gene; 5 Nucleotidase; E NPP; NTPDase; Platelet aggregation; Von Willebrand disease (VWD)

Indexed keywords

5' NUCLEOTIDASE; ACID ANHYDRIDE HYDROLASE; ADENINE NUCLEOTIDE; ALPHA2 INTEGRIN; ECTO NUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE; GENOMIC DNA; LACTATE DEHYDROGENASE; NUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE; NUCLEOTIDE PYROPHOSPHATASE; PHOSPHODIESTERASE; RISTOCETIN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 2; HYDROLASE; INORGANIC PYROPHOSPHATASE; NUCLEOSIDE TRIPHOSPHATASE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA ISOLATION; ENZYME ACTIVITY; FEMALE; GENETIC POLYMORPHISM; HUMAN; HYDROLYSIS; MALE; PARTIAL THROMBOPLASTIN TIME; POLYMERASE CHAIN REACTION; PROTHROMBIN TIME; THROMBOCYTE; THROMBOCYTE ADHESIVENESS; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; THROMBOCYTE POOR PLASMA; THROMBOCYTE RICH PLASMA; VON WILLEBRAND DISEASE; ADOLESCENT; BLOOD; BRAZIL; CASE CONTROL STUDY; CHILD; ENZYMOLOGY; GENE FREQUENCY; GENETICS; GENOTYPE; HEMOSTASIS; PHENOTYPE; YOUNG ADULT;

5'-NUCLEOTIDASE; ADENINE NUCLEOTIDES; ADOLESCENT; ADULT; BLOOD PLATELETS; BRAZIL; CASE-CONTROL STUDIES; CHILD; FEMALE; GENE FREQUENCY; GENOTYPE; HEMOSTASIS; HUMANS; HYDROLASES; HYDROLYSIS; INTEGRIN ALPHA2; INTEGRIN ALPHA2BETA1; MALE; NUCLEOSIDE-TRIPHOSPHATASE; PARTIAL THROMBOPLASTIN TIME; PHENOTYPE; PHOSPHORIC DIESTER HYDROLASES; PLATELET AGGREGATION; PLATELET COUNT; POLYMORPHISM, GENETIC; PROTHROMBIN TIME; PYROPHOSPHATASES; VON WILLEBRAND DISEASES; YOUNG ADULT;

EID: 77954423830     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-010-0424-7     Document Type: Article

References (49)

1. P Kouides Kreuz Wolfhart 2009 Diagnosis and management of inherited von Willebrand disease in the next decade: a clinical perspective Thromb Res 124 1 10.1016/S0049-3848(09)00520-9
2. S Trasi S Shetty K Ghosh D Mohanty 2005 Prevalence & spectrum of von Willebrand disease from western India Indian J Med Res 121 653 658 15937368
3. AJ Reininger 2008 VWF attributes-impact on thrombus formation Thromb Res 4 S9 S13 10.1016/S0049-3848(08)70028-8
4. A Totonchi Y Eshraghi D Beck K Mccrae B Guyuron 2008 Von Willebrand disease: screening, diagnosis, and management Aesthet Surg J 2 189 194 10.1016/j.asj.2007.12.002 (Pubitemid 351434644)
5. WL Nichols MB Hultin AH James MJ Manco-Johnson RR Montgomery TL Ortel ME Rick JE Sadler M Weinstein B Yawn 2008 Von Willebrand disease (VWD): evidence-based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA) Haemophilia 14 171 232 10.1111/j.1365-2516.2007.01643.x 1:CAS:528:DC%2BD1cXksFSnsbc%3D 18315614 (Pubitemid 351343618)
6. AJ Marcus MJ Broekmann JFH Drosopoulos N Islam DJ Pinsky C Sesti R Levi 2003 Heterologous cell-cell interactions: thromboregulation, cerebroprotection and cardioprotection by CD39 (NTPDase 1) J Thromb Haemost 12 2497 2509 10.1111/j.1538-7836.2003.00479.x
7. 2+ and cyclic adenosine monophosphatase-dependent signaling in endothelial exocytosis Blood 1 118 127
8. H Zimmermann 1999 Nucleotides and CD39: principal modulatory players in hemostasis and thrombosis Nat Med 9 987 988 10.1038/12419 (Pubitemid 29439562)
9. RK Andrews M Berndt 2004 Platelet physiology and thrombosis Thromb Res 114 447 453 10.1016/j.thromres.2004.07.020 1:CAS:528:DC%2BD2cXovVKms7o%3D 15507277 (Pubitemid 39422578)
10. AP Reiner DS Siscovick FR Rosendaal 2001 Platelet glycoprotein gene polymorphisms and risk of thrombosis: facts and fancies Rev Clin Exp Hematol 53 262 287 10.1046/j.1468-0734.2001.00045.x (Pubitemid 34947706)
11. M Kritzik B Savage DJ Nugent S Santoso ZM Ruggeri TJ Kunicki 1998 Nucleotide polymorphisms in the α2 gene define multiple alleles that are associated with differences in platelets α2β1 density Blood 7 2382 2388
12. E Konurcu N Erginel-Unaltuna 2002 Platelet glycoprotein Ia 807C/T (Phe224) and 873G/A (Thr246) dimorphisms in Turkey Am J Hematol 69 83 84 10.1002/ajh.10029 (Pubitemid 34008237)
13. S Santoso 2001 Platelet polymorphisms in thrombotic disorders Transfus Clin Biol 8 261 266 10.1016/S1246-7820(01)00123-9 1:STN:280: DC%2BD3MvltlOrsw%3D%3D 11499974 (Pubitemid 32672987)
14. J Di Paola AB Federici PM Mannucci MT Canciani M Kritzik Kunicki Tj D Nugent 1999 Low platelet α2β1 levels in type I von Willebrand disease correlate with impaired platelet function in a high shear stress system Blood 93 3578 3582 1:CAS:528:DyaK1MXjsVOns7o%3D 10339461
15. C Pilla T Emanuelli SS Frasetto AMO Battastini RD Dias JJF Sarkis 1996 ATP diphosphohydrolase activity (apyrase, EC 3.6.1.5) in human blood platelets Platelets 7 225 230 10.3109/09537109609023582 1:CAS:528:DyaK28XntFGjsLo%3D
16. MC Araújo JB Rocha A Morsch R Zanin R Bauchspiess VM Morsch MRC Schetinger 2005 Enzymes that hydrolyze adenine nucleotides in platelets from breast cancer patients Biochim Biophys Acta 1740 421 426
17. JW Goding B Grobben H Slegers 2003 Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/phosphodiesterase family Biochim Biophys Acta 1638 1 19 1:CAS:528:DC%2BD3sXjvFahsb0%3D 12757929
18. A Cimpean C Stefan R Gijsbers W Stalmans M Bollen 2004 Substrate-specifying determinants of the nucleotide pyrophosphatases/ phosphodiesterases NPP1 and NPP2 Biochemical J 381 71 77 10.1042/BJ20040465 1:CAS:528:DC%2BD2cXls1Onur4%3D (Pubitemid 38932212)
19. BA Bouchard S Butenas KG Mann 2002 Interactions between platelets and the coagulation system Platelets 48 229 253
20. GL Lunkes D Lunkes F Stefanello A Morsch VM Morsch CM Mazzanto MRC Schetinger 2003 Enzymes that hydrolyze adenine nucleotides in diabetes and associated pathologies Thromb Res 109 189 194 10.1016/S0049-3848(03)00178-6 1:CAS:528:DC%2BD3sXjvFekt7c%3D 12757773 (Pubitemid 36712907)
21. ZM Ruggeri 1997 Mechanisms initiating platelet thrombus formation Thromb Haemost 78 611 616 1:CAS:528:DyaK2sXktFelurg%3D 9198225
22. AC Silva A Morsch R Zanin MC Correa LC Arantes MC Araújo VM Morsch MRC Schetinger 2005 Enzymes that hydrolysis adenine nucleotides in chronic renal failure: relationship between defects and renal failure severity Biochim Biophys Acta 1741 282 288 1:CAS:528:DC%2BD2MXhtVegurjN 16019192
23. MMF Duarte VL Loro JBT Rocha DBR Leal AF Bem A Dorneles VM Morsch MRC Schetinger 2007 Enzymes that hydrolyze adenine nucleotides of patients with hypercholesterolemia and inflammatory process FEBS J 274 2707 2714 10.1111/j.1742-4658.2007.05805.x 1:CAS:528:DC%2BD2sXmvVWrtLo%3D 17451439 (Pubitemid 46800541)
24. MD Bagatini CC Martins V Battisti RM Spanevello D Gasparetto CS Rosa JF Gonçalves MRC Schetinger RB Santos VM Morsch 2008 Hydrolysis of adenine nucleotides in platelets from patients with acute myocardial infarction Clin Biochem 41 1181 1185 10.1016/j.clinbiochem.2008.07.008 1:CAS:528: DC%2BD1cXhtlyhsbnK 18692493
25. GI Bell JH Karam WJ Rutter 1981 Polymorphic DNA region adjacent to the 5′ end of the human insulin gene Proc Natl Acad Sci USA 78 5759 5763 10.1073/pnas.78.9.5759 1:CAS:528:DyaL3MXlvVClt7w%3D 6272317
26. M Gross-Bellar P Oudet P Chambon 1973 Isolation of high-molecular-weight DNA from mammalian cells Eur J Biochem 36 32 38 10.1111/j.1432-1033.1973. tb02881.x
27. MM Bradford 1976 A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 218 254 10.1016/0003-2697(76)90527-3
28. 2+-ATPase activity Anal Biochem 157 375 380 10.1016/0003-2697(86) 90640-8 1:CAS:528:DyaL28XlvVKgtL0%3D 2946250
29. CR Fürstenau DS Trentin MLM Barreto-chaves JJ Sarkis 2006 Ecto-nucleotide pyrophosphatase/phosphodiesterase as a part of multiple system for nucleotide hydrolysis by platelets from rats: kinetic characterization and biochemical properties Platelets 17 84 91 10.1080/09537100500246641 16421009 (Pubitemid 43155614)
30. A Tosetto G Castaman F Rodeghiero 2007 Assessing bleeding in von Willebrand disease with bleeding score Blood 21 89 97 10.1016/j.blre.2006.04.002 (Pubitemid 46428464)
31. I Ramasamy 2004 Inherited bleeding disorders: disorders of platelet adhesion and aggregation Crit Rev Oncol Hematol 49 1 35 10.1016/S1040-8428(03) 00117-3 14734152 (Pubitemid 38088017)
32. Brasil, Ministério da Saúde, Secretaria de Atenção à Saúde, Departamento de Atenção Especializada (2006) Manual de diagnóstico e tratamento da doença de Von Willebrand 1-44
33. S Giannini AM Mezzasoma M Leone P Gresele 2007 Laboratory diagnosis and monitoring of desmopressin treatment of von Willebrand's disease by flow cytometry Hematol J 92 1647 1654 1:CAS:528:DC%2BD1cXitVajtQ%3D%3D
34. Italian Working Group 1977 Spectrum of von Willebrand disease: a study of 100 cases Br J Haematol 35 101 112 10.1111/j.1365-2141.1977.tb00566.x
35. H Ni J Freedmann 2003 Platelets in hemostasis and thrombosis: role of integrins and their ligands Transfus Apher Sci 28 257 264 10.1016/S1473-0502(03) 00044-2 12725952 (Pubitemid 36506500)
36. TJ Kunick M Kritzik DS Annis DJ Nugent 1997 Hereditary variation in platelet integrin α2β1 density is associated with two silent polymorphisms in the α2 gene coding sequence Blood 89 1939 1943
37. AP Reiner KM Aramaki G Teramura L Gaur 1998 Analysis of platelet glycoprotein Ia (α2 integrin) allele frequencies in three North American populations reveals genetic association between nucleotide 807C/T and amino acid 505 Glu/Lys (HPA-5) dimorphisms Thromb Haemost 80 449 456 1:CAS:528: DyaK1cXmtFCls7Y%3D 9759626
38. DM Dinauer KD Friedman MJ Hessner 1999 Allelic distribution of the glycoprotein Ia (α2 integrin) C807T/G873A dimorphisms among Caucasian venous thrombosis patients and six racial groups Br J Haematol 107 563 565 10.1046/j.1365-2141.1999.01753.x 1:CAS:528:DC%2BD3cXhtlKhsw%3D%3D 10583259
39. I Canobbio C Balduini M Torti 2004 Signalling through the platelet glycoprotein Ib-V-IX complex Cell Signal 16 1329 1334 10.1016/j.cellsig.2004.05. 008 1:CAS:528:DC%2BD2cXnslentbo%3D 15381249 (Pubitemid 39277499)
40. RW Farndale JJ Sixma MJ Barness PG De Groot 2004 The role of collagen in thrombosis and haemostasis J Thromb Haemost 2 561 573 10.1111/j.1538-7836.2004. 00665.x 1:CAS:528:DC%2BD2cXjslWntLs%3D 15102010 (Pubitemid 40185679)
41. JM Gibbins 2004 Platelet adhesion signaling and the regulation of thrombus formation J Cell Sci 117 3415 3425 10.1242/jcs.01325 1:CAS:528:DC%2BD2cXntFersLk%3D 15252124 (Pubitemid 39206382)
42. A Kasirer-Friede MR Cozzi M Mazzucato L De Marco ZM Ruggeri S Shattil 2004 Signaling through GP Ib-IX-V activates alpha IIb beta 3 independently of other receptors Blood 103 3403 3411 10.1182/blood-2003-10-3664 1:CAS:528:DC%2BD2cXjslKgtrs%3D 14726383 (Pubitemid 38525671)
43. SC Robson J Sévigny M Imai O Guckelberger K Enjyoji 2000 Thromboregulatory potential of endothelial CD39/nucleoside triphosphate diphosphohydrolase: modulation of purinergic signaling in platelets Cardiovasc Renal 2 1 17
44. AJ Marcus LB Safir KA Hajjar 1991 Inhibition of platelet function by an aspirin-insensitive endothelial cell ADPase: thromboregulation by endothelial cells J Clin Invest 88 1690 1696 10.1172/JCI115485 1:CAS:528: DyaK38XjsVWlug%3D%3D 1939654
45. E Kaczmarek K Koziak J Sévigny JB Siegel J Anrather AR Beaudon FH Bach 1996 Identification and characterization of CD39 vascular ATP diphosphohydrolase J Biol Chem 271 33116 33122 10.1074/jbc.271.51.33116 1:CAS:528:DyaK2sXnvVam 8955160 (Pubitemid 27008752)
46. AJ Marcus MJ Broekman JH Drosopoulos N Islam TN Alyonycheva LB Safier KA Hajjar 1997 The endothelial cell ecto-ADPase responsible for inhibition of platelet function is CD39 J Clin Invest 996 1351 1360 10.1172/JCI119294
47. F Di Virgilio P Chiozzi D Ferrari S Falzoni JM Sanz A Morelli M Torboli G Bolognesi OR Baricord 2001 Nucleotide receptors: an emerging family of regulatory molecules in blood cells Blood 97 587 600 10.1182/blood.V97.3.587 1:CAS:528:DC%2BD3MXhtVSjs7Y%3D 11157473 (Pubitemid 32113390)
48. J Gordon 1986 Extracellular ATP: effects, sources and fate Biochem J 233 309 319 1:CAS:528:DyaL28XmsVansQ%3D%3D 3006665
49. PA Maldonado MC Corrêa LV Becker C Flores MB Moretto VM Morsch MRC Schetinger 2008 Ectonucleotide pyrophosphatase/phosphodiesterase (E-NPP) and adenosine deaminase (ADA) activities in patients with uterine cervix neoplasia Clin Biochem 41 400 406 10.1016/j.clinbiochem.2007.12.019 1:CAS:528: DC%2BD1cXjs1Sku7w%3D