Safety and efficacy of pegylated interferon and ribavirin in adolescents with human immunodeficiency virus and hepatitis C virus acquired perinatally

Journal of Medical Virology

Volumn 82, Issue 7, 2010, Pages 1110-1114

  Rosso, Raffaella ^a   Di Biagio, Antonio ^a   Mikulska, Malgorzata ^a   Nicco, Elena ^a   Bernardini, Claudia ^a   Viscoli, Claudio ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

Adolescents; Hepatitis C virus; Human immunodeficiency virus; Mother to child transmission; Pegylated interferon; Perinatal transmission; Ribavirin

Indexed keywords

ABACAVIR; ATAZANAVIR; EFAVIRENZ; EMTRICITABINE; LAMIVUDINE; PEGINTERFERON ALPHA2A; RIBAVIRIN; RITONAVIR; TENOFOVIR; ALPHA INTERFERON; ALPHA2A INTERFERON; ANTIVIRUS AGENT; MACROGOL DERIVATIVE; RECOMBINANT PROTEIN;

ADOLESCENT; ADULT; ARTICLE; CASE REPORT; CD4 LYMPHOCYTE COUNT; DISEASE TRANSMISSION; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; FATIGUE; HEPATITIS C; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INJECTION SITE REACTION; LABORATORY TEST; MALE; MIXED INFECTION; MONOTHERAPY; PERINATAL PERIOD; VIRUS LOAD; VIRUS REPLICATION; COMPLICATION; DRUG COMBINATION; FEMALE; HEPACIVIRUS; HEPATITIS C, CHRONIC; HUMAN IMMUNODEFICIENCY VIRUS 1; TRANSMISSION; TREATMENT OUTCOME; VERTICAL TRANSMISSION;

HEPATITIS C VIRUS; HUMAN IMMUNODEFICIENCY VIRUS;

ADOLESCENT; ANTIVIRAL AGENTS; DRUG THERAPY, COMBINATION; FEMALE; HEPACIVIRUS; HEPATITIS C, CHRONIC; HIV INFECTIONS; HIV-1; HUMANS; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; INTERFERON-ALPHA; MALE; POLYETHYLENE GLYCOLS; RECOMBINANT PROTEINS; RIBAVIRIN; TREATMENT OUTCOME;

EID: 77954416651     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.21802     Document Type: Article

References (15)

1. Alter MJ. 2006. Epidemiology of viral hepatitis and HIV co-infection. J Hepatol 44:S6-S9. (Pubitemid 43053865)
2. Benhamou Y, Bochet M, Di Martino V, Charlotte F, Azria F, Coutellier A, Vidaud M, Bricaire F, Opolon P, Katlama C, Poynard T. 1999. Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus co-infected patients. Hepatology 30:1054-1058. (Pubitemid 29458296)
3. Chung RT, Andersen J, Volberding P, Robbins GK, Liu T, Sherman KE, Peters MG, Koziel MJ, Bhan AK, Alston B, Colquhoun D, Nevin T, Harb G, van der Horst C, AIDS Clinical Trials Group A5071 Study Team. 2004. Peginterferon alfa 2a plus ribavirin versus interferon alfa-2a plus ribavirin for chronic hepatitis C in HIV-coinfected persons. N Engl J Med 351:451-459.
4. Daar ES, Lynn H, Donfield S, Gomperts E, Hilgartner MW, Hoots WK, Chernoff D, Arkin S, Wong WY, Winkler CA. 2001. Hemophilia Growth and Development Study 2001. Relation between HIV-1 and hepatitis C viral load in patients with hemophilia. J Acquir Immune Defic Syndr 26:466-472.
5. England K, Thorne C, Newell ML. 2006. Vertically acquired pediatric coinfection with HIV and hepatitis C virus. Lancet Infect Dis 6: 83-90. (Pubitemid 43138906)
6. England K, Thorne C, Pembrey L, Newell ML. 2009. Policies and practices for the clinical management of HIV/HCV coinfected children in Europe: An epidemiological survey. Eur J Pediatr 168:915-917.
7. Jacobson KR, Murray K, Zellos A, Schwarz KB. 2002. An analysis of published trials of interferon monotherapy in children with chronic hepatitis C. J Pediatr Gastroenterol Nutr 34: 52-58. (Pubitemid 34251703)
8. Landes M, Newell ML, Barlow P, Fiore S, Malyuta R, Martinelli P, Posokhova S, Savasi V, Semenenko I, Stelmah A, Tibaldi C, Thorne C. 2008. Hepatitis B or hepatitis C coinfection in HIV-infected pregnant women in Europe. HIV Med 9:526-534.
9. Nelson M, Matthews G, Brook MG, Main J, Bateman P, Olson R, Sabin C, Wilkins E. 2005. BHIVA guidelines on HIV and chronic hepatitis: Coinfection with HIV and hepatitis C virus infection. HIV Med 6:96-106. (Pubitemid 41038588)
10. Quesnel-Vallières M, Lemay M, Lapointe N, Martin SR, Soudeyns H. 2008. HCV quasi species evolution during treatment with interferon alfa-2b and ribavirin in two children coinfected with HCV and HIV-1. J Clin Virol 43:236-240.
11. Resti M, Jara P, Hierro L, Azzari C, Giacchino R, Zuin G, Zancan L, Pedditzi S, Bortolotti F. 2003. Clinical features and progression of perinatally acquired hepatitis C virus infection. J Med Virol 70: 373-377. (Pubitemid 36638049)
12. Rockstroh JK, Bhagani S, Benhamou Y, Bruno R, Mauss S, Peters L, Puoti M, Soriano V, Tural C, EACS Executive Committee. 2008. European AIDS Clinical Society (EACS) guidelines for the clinical management and treatment of chronic hepatitis B and C coinfection in HIV-infected adults. HIV Med 9:82-88. (Pubitemid 351228130)
13. Shire NJ, Welge JA, Sherman KE. 2007. Response rates to pegylated interferon and ribavirin in HCV/HIV coinfection: A research synthesis. J Viral Hepat 14:239-248.
14. Sulkowski MS. 2008. Viral hepatitis and HIV coinfection. J Hepatol 48:353-367.
15. Sulkowski MS, Benhamou Y. 2007. Therapeutic issues in HIV/HCVcoinfected patients. J Viral Hepat 14:371-386.