High-dose hook effect in six automated human chorionic gonadotrophin assays

Annals of Clinical Biochemistry

Volumn 47, Issue 4, 2010, Pages 383-385

  Al Mahdili, Huda A ^a   Jones, Graham R D ^a,b  

^a ST VINCENT S HOSPITAL   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CHORIONIC GONADOTROPIN;

ARTICLE; AUTOMATION; CASE REPORT; CONTROLLED STUDY; HIGH DOSE HOOK EFFECT; HORMONE DETERMINATION; HUMAN; IMMUNOASSAY; INTERMETHOD COMPARISON; MALE; PERFORMANCE; PHENOMENOLOGY; PRIORITY JOURNAL;

ARTIFACTS; AUTOMATION; CHORIONIC GONADOTROPIN; FALSE NEGATIVE REACTIONS; HUMANS; IMMUNOASSAY; MALE;

EID: 77954392075     PISSN: 00045632     EISSN: 00045632     Source Type: Journal    
DOI: 10.1258/acb.2010.090304     Document Type: Article

References (8)

1. O'Reilly SM, Rustin GJS. Mismanagement of choriocarcinoma due to a false low HCG measurement. Int J Gynecol Cancer 1993;3:186-8
2. Miles LE, Lipschitz DA, Bieber CP, Cook JD. Measurements of serum ferritin by a two-site immunoradiometric assay. Anal Biochem 1974;61:209-24
3. Leboeuf R, Langlois M-F, Martin M, Ahnadi CE, Fink GD. Hook effect in calcitonin immunoradiometric assay in patients with metastatic medullary thyroid carcinoma: a case report and review of the literature. J Clin Endocrinol Metab 2006;91:361-4 (Pubitemid 43236893)
4. Yoo A, Zaccaro J. Falsely low serum HCG Level in a patient with hydatidiform mole caused by the high-dose hook effect. Lab Med 2008;31
5. Selby C. Interference in immunoassay. Ann Clin Biochem 1999;36:704-21
6. Sturgeon CM, Berger P, Bidart J-M, et al.: Differences in recognition of the 1st WHO International Reference Reagents for hCG-related isoforms by diagnostic immunoassays for human chorionic gonadotrophin. Clin Chem 2009;55:1484-91
7. Muller CY, Cole LA. The quagmire of hCG and hCG testing in gynaecologic oncology. Gynecol Oncol 2009;112:663-72
8. Cole LA. Human chorionic gonadotrophin (hCG) assay. US hCG reference services