The novel antidepressant agomelatine normalizes hippocampal neuronal activity and promotes neurogenesis in chronically stressed rats

CNS Neuroscience and Therapeutics

Volumn 16, Issue 4, 2010, Pages 195-207

  Dagyte, Girstaute ^a   Trentani, Andrea ^a   Postema, Folkert ^a   Luiten, Paul G ^a   Den Boer, Johan A ^a   Gabriel, Cecilia ^b   Mocaër, Elisabeth ^b   Meerlo, Peter ^a   Van Der Zee, Eddy A ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

Affective disorders; c Fos; Chronic footshock stress; DCX; Hippocampal cell proliferation; Hippocampal cell survival; HPA axis

Indexed keywords

AGOMELATINE; CORTICOSTERONE; CORTICOTROPIN; DOUBLECORTIN; PROTEIN C FOS; ACETAMIDE DERIVATIVE; ANTIDEPRESSANT AGENT; BROXURIDINE; DOUBLECORTIN PROTEIN; KI 67 ANTIGEN; MICROTUBULE ASSOCIATED PROTEIN; NEUROPEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC STRESS; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOTROPIN BLOOD LEVEL; DENTATE GYRUS; DEPRESSION; FOOD INTAKE; FOOTSHOCK; HIPPOCAMPUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNOHISTOCHEMISTRY; MALE; MOOD DISORDER; NERVE CELL EXCITABILITY; NERVE CELL GROWTH; NERVE CELL PLASTICITY; NONHUMAN; RAT; ANALYSIS OF VARIANCE; ANIMAL; DISEASE MODEL; DRUG EFFECTS; DRUG THERAPY; EATING; ELECTROSHOCK; GENE EXPRESSION REGULATION; MENTAL STRESS; METABOLISM; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; PATHOLOGY; PATHOPHYSIOLOGY; WISTAR RAT;

ACETAMIDES; ADRENOCORTICOTROPIC HORMONE; ANALYSIS OF VARIANCE; ANIMALS; ANTIDEPRESSIVE AGENTS; BODY WEIGHT; BROMODEOXYURIDINE; CORTICOSTERONE; DISEASE MODELS, ANIMAL; EATING; ELECTROSHOCK; GENE EXPRESSION REGULATION; HIPPOCAMPUS; KI-67 ANTIGEN; MALE; MICROTUBULE-ASSOCIATED PROTEINS; NEUROGENESIS; NEURONS; NEUROPEPTIDES; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR; STRESS, PSYCHOLOGICAL;

EID: 77954380113     PISSN: 17555930     EISSN: 17555949     Source Type: Journal    
DOI: 10.1111/j.1755-5949.2009.00125.x     Document Type: Article

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