Sensitivity and specificity of fasting ammonia and serum bile acids in the diagnosis of portosystemic shunts in dogs and cats

Veterinary Clinical Pathology

Volumn 39, Issue 1, 2010, Pages 57-64

  Ruland, Kristina ^a   Fischer, Andrea ^a   Hartmann, Katrin ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Ammonia; Bile acids; Diagnostic accuracy; Hepatic insufficiency; Portosystemic shunt

Indexed keywords

AMMONIA; BILE ACID;

ANIMAL; ANIMAL DISEASE; ARTERIOVENOUS MALFORMATION; ARTICLE; BLOOD; CAT; CAT DISEASE; CONGENITAL MALFORMATION; DOG; DOG DISEASE; FEMALE; FOOD DEPRIVATION; MALE; PORTAL VEIN; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY;

AMMONIA; ANIMALS; ARTERIOVENOUS MALFORMATIONS; BILE ACIDS AND SALTS; CAT DISEASES; CATS; DOG DISEASES; DOGS; FEMALE; FOOD DEPRIVATION; MALE; PORTAL SYSTEM; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY;

ANIMALIA; CANIS FAMILIARIS;

EID: 77954374592     PISSN: 02756382     EISSN: 1939165X     Source Type: Journal    
DOI: 10.1111/j.1939-165X.2009.00178.x     Document Type: Article

References (40)

1. Center SA. Liver function tests in the diagnosis of portosystemic vascular anomalies. Semin Vet Med Surg (Small Anim) 1990, 5:94-99.
2. Martin RA. Congenital portosystemic shunts in the dog and cat. Vet Clin North Am Small Anim Pract 1993, 23:609-623.
3. Taboada J, Dimski DS. Hepatic encephalopathy: clinical signs, pathogenesis, and treatment. Vet Clin North Am Small Anim Pract 1995, 25:337-355.
4. Leveille-Webster C. History, clinical signs, and physical findings in hepatobiliary disease. Textbook of Veterinary Internal Medicine 2005, 1422-1434. Ettinger SJFeldman EC. eds, 6th ed, Philadelphia, Elsevier Saunders
5. Center SA, Magne ML. Historical, physical examination, and clinicopathologic features of portosystemic vascular anomalies in the dog and cat. Semin Vet Med Surg (Small Anim) 1990, 5:83-93.
6. Strombeck DR, Meyer DJ, Freedland RA. Hyperammonemia due to a urea cycle enzyme deficiency in two dogs. J Am Vet Med Assoc 1975, 166:1109-1111.
7. Zandvliet MJM, Rothuizen J. Transient hyperammonemia due to urea cycle enzyme deficiency in irish wolfhounds. J Vet Intern Med 2007, 21:215-218.
8. Morris J, Rogers Q. Ammonia intoxication in the near adult cat as a result of dietary deficiency of arginine. Science 1978, 199:431-432.
9. Morris J. Nutritional and metabolic responses to arginine deficiency in carnivores. J Nutr 1985, 115:524-531.
10. Jensen AL. Evaluation of fasting and postprandial total serum bile acid concentration in dogs with hepatobiliary disorders. Zentralbl Veterinarmed A 1991, 38:247-254.
11. Gerritzen-Bruning MJ, van den Ingh TS, Rothuizen J. Diagnostic value of fasting plasma ammonia and bile acid concentrations in the identification of portosystemic shunting in dogs. J Vet Intern Med 2006, 20:13-19.
12. Christopher M. Improving the quality of reporting of studies of diagnostic accuracy: let's STARD now [editorial]. Vet Clin Pathol 2007, 36:6.
13. Bossuyt P, Reitsma J, Bruns D. Towards complete and accurate reporting of studies of diagnostic accuracy the STARD initiative. Vet Clin Pathol 2007, 36:8-12.
14. Bossuyt P, Reitsma J, Bruns D. Title: The STARD statement for reporting studies of diagnostic accuracy explanation and elaboration. Clin Chem 2003, 49:7-18.
15. Santilli RA, Gerboni G. Diagnostic imaging of congenital porto-systemic shunts in dogs and cats: a review. Vet J 2003, 166:7-18.
16. Roth L. Comparison of liver cytology and biopsy diagnosis in dogs and cats: 56 cases. Vet Clin Pathol 2001, 30:35-38.
17. Wang K, Panciera D, Al-Rukibat R, Radi Z. Accuracy of ultrasound-guided fine-needle aspiration of the liver and cytologic findings in dogs and cats: 97 cases (1990-2000). J Am Vet Med Assoc 2004, 224:75-78.
18. Gardner I, Greiner M. Receiver-operating characteristic curves and likelihood ratios: improvements over traditional methods for the evaluation and application of veterinary clinical pathology tests. Vet Clin Pathol 2006, 35:8-17.
19. Swets J. Measuring the accuracy of diagnostic systems. Science 1988, 240:1285-1293.
20. Hanley J, Mc Neil B. A method of comparing the areas under receiver operating characteristics curves derived from the same cases. Radiol 1983, 148:839-843.
21. Sackett D, Haynes R, Guyatt G, Tugwell P. Clinical Epidemiology: A Basic Science for Clinical Medicine 1991, 441. 2nd ed, Boston, MA, Little, Brown and Company
22. Koopman P. Confidence limits for the ratio of two binomial proportions. Biometrics 1984, 40:513-517.
23. Hanley J, Mc Neil B. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiol 1982, 143:29-36.
24. Meyer DJ, Strombeck DR, Stone EA, Zenoble RD, Buss DD. Ammonia tolerance test in clinically normal dogs and in dogs with portosystemic shunts. J Am Vet Med Assoc 1978, 173:377-379.
25. Center SA, Baldwin BH, de Lahunta A, Dietze AE, Tennant BC. Evaluation of serum bile acid concentrations for the diagnosis of portosystemic venous anomalies in the dog and cat. J Am Vet Med Assoc 1985, 186:1090-1094.
26. Berger B, Whiting PG, Breznock EM, Bruhl-Day R, Moore PF. Congenital feline portosystemic shunts. J Am Vet Med Assoc 1986, 188:517-521.
27. Johnson CA, Armstrong PJ, Hauptman JG. Congenital portosystemic shunts in dogs: 46 cases (1979-1986). J Am Vet Med Assoc 1987, 191:1478-1483.
28. Walker MC, Hill RC, Guilford WG. Postprandial venous ammonia concentrations in the diagnosis of hepatobiliary disease in dogs. J Vet Intern Med 2001, 15:463-466.
29. Winkler JT, Bohling MW, Tillson DM, Wright JC, Ballagas AJ. Portosystemic shunts: diagnosis, prognosis, and treatment of 64 cases (1993-2001). J Am Anim Hosp Assoc 2003, 39:169-185.
30. Blaxter AC, Holt PE, Pearson GR, Gibbs C, Gruffydd-Jones TJ. Congenital portosystemic shunts in the cat: a report of nine cases. J Small Anim Pract 1988, 29:631-645.
31. Levy JK, Bunch SE, Komtebedde J. Feline portosystemic shunts. Kirk's Current Veterinary Therapy XII: Small Animal Practice 1995, 743-749. Bonagura J,. ed, Philadelphia, PA, WB Saunders Co.
32. Havig M, Tobias KM. Outcome of ameroid constrictor occlusion of single congenital extrahepatic portosystemic shunts in cats: 12 cases (1993-2000). J Am Vet Med Assoc 2002, 220:337-341.
33. Meyer DJ. Liver function tests in dogs with portosystemic shunts: measurement of serum bile acid concentration. J Am Vet Med Assoc 1986, 188:168-169.
34. Center SA, Erb HN, Joseph SA. Measurement of serum bile acids concentrations for diagnosis of hepatobiliary disease in cats. J Am Vet Med Assoc 1995, 207:1048-1054.
35. Kyles AE, Hardie EM, Mehl M, Gregory CR. Evaluation of ameroid ring constrictors for the management of single extrahepatic portosystemic shunts in cats: 23 cases (1996-2001). J Am Vet Med Assoc 2002, 220:1341-1347.
36. Tobias KM, Rohrbach BW. Association of breed with the diagnosis of congenital portosystemic shunts in dogs: 2,400 cases (1980-2002). J Am Vet Med Assoc 2003, 223:1636-1639.
37. Steward P, Batshaw M, Valle D, Walser M. Effects of arginine-free meals on ureagenesis in cats. Am J Pysiol 1981, 241:E:310-E:315.
38. Center SA. Feline hepatic lipidosis. Vet Clin North Am Small Anim Pract 2005, 35:225-269.
39. Rogers Q, Phang J. Deficiency of pyrroline-5-carboxylate synthase in the intestinal mucosa of the cat. J Nutr 1985, 115:146-150.
40. Hitt M, Jones B. Effects of storage temperature and time on canine plasma ammonia concentrations. Am J Vet Res 1986, 47:363-364.