Necrotizing cerebellitis and cerebellar atrophy caused by Neospora caninum infection: Magnetic resonance imaging and clinicopathologic findings in seven dogs

Journal of Veterinary Internal Medicine

Volumn 24, Issue 3, 2010, Pages 571-578

  Garosi, L ^a   Dawson, A ^a   Couturier, J ^a   Matiasek, L ^b   de Stefani, A ^b   Davies, E ^c   Jeffery, N ^d   Smith, P ^e  

^a DAVIES VETERINARY SPECIALISTS   (United Kingdom)

^b ANIMAL HEALTH TRUST   (United Kingdom)

^c QUEEN MOTHER HOSPITAL FOR ANIMALS   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Ataxia; Cerebellum; Labrador Retriever; Masticatory myositis; Neosporosis

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTIPROTOZOAL AGENT; PREDNISOLONE;

ANIMAL; ANIMAL DISEASE; ARTICLE; CEREBELLUM; CEREBELLUM DISEASE; COCCIDIOSIS; DOG; DOG DISEASE; NEOSPORA; NUCLEAR MAGNETIC RESONANCE IMAGING; PARASITOLOGY; PATHOLOGY; RETROSPECTIVE STUDY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIPROTOZOAL AGENTS; CEREBELLAR DISEASES; CEREBELLUM; COCCIDIOSIS; DOG DISEASES; DOGS; MAGNETIC RESONANCE IMAGING; NEOSPORA; PREDNISOLONE; RETROSPECTIVE STUDIES;

ANIMALIA; CANIS FAMILIARIS; NEOSPORA CANINUM;

EID: 77954371577     PISSN: 08916640     EISSN: 19391676     Source Type: Journal    
DOI: 10.1111/j.1939-1676.2010.0485.x     Document Type: Article

References (26)

1. Bjerkus I, Mohn SF, Presthus J. Unidentified cyst forming sporozoon causing encephalitis and myositis in dogs. Z Parasitenkd 1984, 70:271-274.
2. Dubey JP, Lindsay DS. A review of N. caninum and neosporosis. Vet Parasitol 1996, 32:147-151.
3. Dubey JP. Recent advances in Neospora and neosporosis. Vet Parasitol 1999, 84:349-367.
4. Tranas J, Heinzen RA, Weiss LM. Serological evidence of human infection with the protozoan Neospora caninum. Clin Diagn Lab Immunol 1999, 6:765-767.
5. Gaitero L, Añor S, Montoliu P. Detection of Neospora caninum tachyzoites in canine cerebrospinal fluid. J Vet Intern Med 2006, 20:410-414.
6. McAllister MM, Dubey JP, Lindsay DS. Dogs are definitive hosts for N. caninum. Int J Parasitol 1998, 28:1473-1478.
7. Lindsay DS, Dubey JP, Duncan RB. Confirmation that the dog is a definitive host for N. caninum. Vet Parasitol 1999, 82:327-333.
8. Dubey JP, Hattel AL, Lindsay DS. Neonatal Neospora caninum infection in dogs: Isolation of the causative agent and experimental transmission. J Am Vet Med Assoc 1988, 193:1259-1263.
9. Cole RA, Lindsay DS, Blagburn BL. Vertical transmission of N. caninum in dogs. J Parasitol 1995, 81:208-211.
10. Ruehlmann D, Podell M, Oglesbee M. Canine neosporosis: A case report and literature review. J Am Anim Hosp Assoc 1995, 31:174-183.
11. Barber JS, Trees AJ. Naturally occurring vertical transmission of N. caninum in dogs. Int J Parasitol 1998, 28:57-64.
12. Dubey JP, Schares G, Ortega-Mora LM. Epidemiology and control of neosporosis and N. caninum. Clin Microbiol Rev 2007, 20:323-367.
13. Dubey JP, Koestner A, Piper RC. Repeated transplacental transmission of N. caninum in dogs. J Am Vet Med Assoc 1990, 197:857-860.
14. Barber JS, Trees AJ. Clinical aspects of 27 cases of neosporosis in dogs. Vet Rec 1996, 139:439-443.
15. Crookshanks JL, Taylor SM, Haines DM. Treatment of canine pediatric N. caninum myositis following immunohistochemical identification of tachyzoites in muscle biopsies. Can Vet J 2007, 48:506-508.
16. Lorenzo V, Pumarola M, Sisó S. Neosporosis with cerebellar involvement in an adult dog. J Small Anim Prac 2002, 43:76-79.
17. Dubey JP, Carpenter JL, Speer CA. Newly recognized fatal protozoan disease of dogs. J Am Vet Med Assoc 1988, 192:1269-1285.
18. Reichel MP, Ellis JT, Dubey JP. Neosporosis and hammondiosis in dogs. J Small Anim Pract 2007, 48:308-312.
19. Jackson W, DeLahunta A, Adaska J. N. caninum in an adult dog with progressive cerebellar signs. Prog Vet Neurol 1996, 6:1224-1227.
20. Cantile C, Arispici M. Necrotizing cerebellitis due to Neospora caninum infection in an old dog. J Vet Med A Physiol Pathol Clin Med 2002, 49:47-50.
21. Knowler C, Wheeler SJ. Neospora caninum infection in three dogs. J Small Anim Pract 1995, 36:172-177.
22. Barber JS, Payne-Johnson CE, Trees AJ. Distribution of N. caninum within the CNS and other tissues of six dogs with clinical neosporosis. J Small Anim Pract 1996, 37:568-574.
23. Bjerkus I, Presthus J. The neuropathology in toxoplasmosis-like infection caused by a newly recognised cyst-forming sporozoon in dogs. Acta Pathol Microbiol Immunol Scand 1989, 97:459-468.
24. Platt SR, McConnell JF, Garosi LS. Magnetic resonance imaging in the diagnosis of canine inflammatory myopathies in three dogs. Vet Radiol Ultrasound 2006, 47:532-537.
25. Mayhew IG, Smith KC, Dubey JP. Treatment of encephalomyelitis due to N. caninum in a litter of puppies. J Small Anim Pract 1991, 32:609-612.
26. Thate FM, Laanen SC. Successful treatment of neosporosis in an adult dog. Vet Q 1998, 20:113-114.