Eicosapentaenoic acid up-regulates apelin secretion and gene expression in 3T3-L1 adipocytes

Molecular Nutrition and Food Research

Volumn 54, Issue SUPPL. 1, 2010, Pages

  Lorente Cebrián, Silvia ^a   Bustos, Matilde ^b   Marti, Amelia ^a   Martinez, José Alfredo ^a   Moreno Aliaga, María Jesús ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Adipocytes; Akt; Apelin; Eicosapentaenoic acid; Insulin resistance

Indexed keywords

APLN PROTEIN, MOUSE; CARRIER PROTEIN; CYCLOHEXIMIDE; ICOSAPENTAENOIC ACID; MESSENGER RNA; RNA;

ADIPOCYTE; ANIMAL; ARTICLE; CELL STRAIN 3T3; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; ISOLATION AND PURIFICATION; METHODOLOGY; MOUSE; PHYSIOLOGY; POLYMERASE CHAIN REACTION; SECRETION; WESTERN BLOTTING;

3T3 CELLS; ADIPOCYTES; ANIMALS; BLOTTING, WESTERN; CARRIER PROTEINS; CYCLOHEXIMIDE; EICOSAPENTAENOIC ACID; GENE EXPRESSION REGULATION; MICE; POLYMERASE CHAIN REACTION; RNA; RNA, MESSENGER;

MUS;

EID: 77954371184     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200900522     Document Type: Article

References (41)

1. Boucher, J., Masri, B., Daviaud, D., Gesta, S. et al., Apelin, a newly identified adipokine up-regulated by insulin and obesity. Endocrinology 2005, 146, 1764-1771.
2. Daviaud, D., Boucher, J., Gesta, S., Dray, C. et al., TNFalpha up-regulates apelin expression in human and mouse adipose tissue. FASEB J. 2006, 20, 1528-1530.
3. Li, L., Yang, G., Li, Q., Tang, Y. et al., Changes and relations of circulating visfatin, apelin, and resistin levels in normal, impaired glucose tolerance, and type 2 diabetic subjects. Exp. Clin. Endocrinol. Diabetes 2006, 114, 544-548.
4. Castan-Laurell, I., Vitkova, M., Daviaud, D., Dray, C. et al., Effect of hypocaloric diet-induced weight loss in obese women on plasma apelin and adipose tissue expression of apelin and APJ. Eur. J. Endocrinol. 2008, 158, 905-910.
5. Castan-Laurell, I., Boucher, J., Dray, C., Daviaud, D. et al., Apelin, a novel adipokine over-produced in obesity: friend or foe? Mol. Cell. Endocrinol. 2005, 245, 7-9.
6. Carpéné, C., Dray, C., Attané, C., Valet, P. et al., Expanding role for the apelin/APJ system in physiopathology. J. Physiol. Biochem. 2007, 63, 359-373.
7. Dray, C., Knauf, C., Daviaud, D., Waget, A. et al., Apelin stimulates glucose utilization in normal and obese insulinresistant mice. Cell Metab. 2008, 8, 437-445.
8. Kralisch, S., Lossner, U., Bluher, M., Paschke, R. et al., Growth hormone induces apelin mRNA expression and secretion in mouse 3T3-L1 adipocytes. Regul. Pept. 2007, 139, 84-89.
9. Wei, L., Hou, X., Tatemoto, K., Regulation of apelin mRNA expression by insulin and glucocorticoids in mouse 3T3-L1 adipocytes. Regul. Pept. 2005, 132, 27-32.
10. Hotamisligil, G. S., Shargill, N. S., Spiegelman, B. M., Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993, 259, 87-91.
11. Mori, T. A., Bao, D. Q., Burke, V., Puddey, I. B. et al., Dietary fish as a major component of a weight-loss diet: effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects. Am. J. Clin. Nutr. 1999, 70, 817-825.
12. Mori, T. A., Beilin, L. J., Omega-3 fatty acids and inflammation. Curr. Atheroscler. Rep. 2004, 6, 461-467.
13. Flachs, P., Rossmeisl, M., Bryhn, M., Kopecky, J., Cellular and molecular effects of n-3 polyunsaturated fatty acids on adipose tissue biology and metabolism. Clin. Sci. (Lond.) 2009, 116, 1-16.
14. Pérez-Matute, P., Marti, A., Martínez, J. A., Fernández-Otero, M. P. et al., Eicosapentaenoic fatty acid increases leptin secretion from primary cultured rat adipocytes: role of glucose metabolism. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2005, 288, R1682-R1688.
15. Lorente-Cebrian, S., Perez-Matute, P., Martinez, J. A., Marti, A., Moreno-Aliaga, M. J., Effects of eicosapentaenoic acid (EPA) on adiponectin gene expression and secretion in primary cultured rat adipocytes. J. Physiol. Biochem. 2006, 62, 61-69.
16. Flachs, P., Mohamed-Ali, V., Horakova, O., Rossmeisl, M. et al., Polyunsaturated fatty acids of marine origin induce adiponectin in mice fed a high-fat diet. Diabetologia 2006, 49, 394-397.
17. Pérez-Matute, P., Pérez-Echarri, N., Martínez, J. A., Marti, A., Moreno-Aliaga, M. J., Eicosapentaenoic acid actions on adiposity and insulin resistance in control and high-fat-fed rats: role of apoptosis, adiponectin and tumour necrosis factor-alpha. Br. J. Nutr. 2007, 97, 389-398.
18. Moreno-Aliaga, M. J., Pérez-Echarri, M. N., Pérez-Matute, P., Marcos, B. et al., Effects of EPA ethyl ester on visfatin and apelin in control and diet-induced obese (DIO) rats. Diabetes 2008, 59, A2574-PO.
19. Moreno-Aliaga, M. J., Matsumura, F., Effects of 1,1,1- trichloro-2,2-bis(p-chlorophenyl)-ethane (p,p0-DDT) on 3T3- L1 and 3T3-F442A adipocyte differentiation. Biochem. Pharmacol. 2002, 63, 997-1007.
20. Lorente-Cebrian, S., Bustos, M., Marti, A., Martinez, J. A., Moreno-Aliaga, M. J., Eicosapentaenoic acid stimulates AMP-activated protein kinase and increases visfatin secretion in cultured murine adipocytes. Clin. Sci. (Lond.) 2009, 117, 243-249.
21. Porstmann, T., Kiessig, S. T., Enzyme immunoassay techniques. An overview. J. Immunol. Methods 1992, 150, 5-21.
22. Bustos, M., Beraza, N., Lasarte, J. J., Baixeras, E. et al., Protection against liver damage by cardiotrophin-1: a hepatocyte survival factor up-regulated in the regenerating liver in rats. Gastroenterology 2003, 125, 192-201.
23. Ishiguro, J., Tada, T., Ogihara, T., Mizota, M. et al., Metabolism of ethyl eicosapentaenoate (EPA-E) in rats and effect of its metabolites on ellagic acid-induced thrombus formation in the stenosed femoral artery of rabbits. Chem. Pharm. Bull. (Tokyo) 1988, 36, 2158-2167.
24. Tanabe, Y., Matsunaga, Y., Saito, M., Nakayama, K., Involvement of cyclooxygenase-2 in synergistic effect of cyclic stretching and eicosapentaenoic acid on adipocyte differentiation. J. Pharmacol. Sci. 2008, 106, 478-484.
25. Murata, M., Kaji, H., Takahashi, Y., Iida, K. et al., Stimulation by eicosapentaenoic acids of leptin mRNA expression and its secretion in mouse 3T3-L1 adipocytes in vitro. Biochem. Biophys. Res. Commun. 2000, 270, 343-348.
26. Itoh, M., Suganami, T., Satoh, N., Tanimoto-Koyama, K. et al., Increased adiponectin secretion by highly purified eicosapentaenoic acid in rodent models of obesity and human obese subjects. Arterioscler. Thromb. Vasc. Biol. 2007, 27, 1918-1925.
27. Glassford, A. J., Yue, P., Sheikh, A. Y., Chun, H. J. et al., HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes. Am. J. Physiol. Endocrinol. Metab. 2007, 293, E1590-E1596.
28. Gonzalez, E., McGraw, T. E., Insulin signaling diverges into Akt-dependent and -independent signals to regulate the recruitment/docking and the fusion of GLUT4 vesicles to the plasma membrane. Mol. Biol. Cell 2006, 17, 4484-4493.
29. Murata, M., Kaji, H., Iida, K., Okimura, Y., Chihara, K., Dual action of eicosapentaenoic acid in hepatoma cells: upregulation of metabolic action of insulin and inhibition of cell proliferation. J. Biol. Chem. 2001, 276, 31422-31428.
30. Bradley, R. L., Cheatham, B., Regulation of ob gene expression and leptin secretion by insulin and dexamethasone in rat adipocytes. Diabetes 1999, 48, 272-278.
31. Roh, C., Thoidis, G., Farmer, S. R., Kandror, K. V., Identification and characterization of leptin-containing intracellular compartment in rat adipose cells. Am. J. Physiol. Endocrinol. Metab. 2000, 279, E893-E899.
32. Ronkainen, V. P., Ronkainen, J. J., Hanninen, S. L., Leskinen, H. et al., Hypoxia inducible factor regulates the cardiac expression and secretion of apelin. FASEB J. 2007, 21, 1821-1830.
33. Soria, L. R., Gradilone, S. A., Larocca, M. C., Marinelli, R. A., Glucagon induces the gene expression of aquaporin-8 but not that of aquaporin-9 water channels in the rat hepatocyte. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2009, 296, R1274-R1281.
34. Vickers, C., Hales, P., Kaushik, V., Dick, L. et al., Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J. Biol. Chem. 2002, 277, 14838-14843.
35. Kumar, K. V., Das, U. N., Effect of cis-unsaturated fatty acids, prostaglandins, and free radicals on angiotensinconverting enzyme activity in vitro. Proc. Soc. Exp. Biol. Med. 1997, 214, 374-379.
36. Das, U. N., Essential fatty acids and their metabolites could function as endogenous HMG-CoA reductase and ACE enzyme inhibitors, anti-arrhythmic, anti-hypertensive, antiatherosclerotic, anti-inflammatory, cytoprotective, and cardioprotective molecules. Lipids Health Dis. 2008, 7, 37.
37. Gupte, M., Boustany-Kari, C. M., Bharadwaj, K., Police, S. et al., ACE2 is expressed in mouse adipocytes and regulated by a high-fat diet. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2008, 295, R781-R788.
38. Perez-Matute, P., Marti, A., Martinez, J. A., Moreno-Aliaga, M. J., Effects of arachidonic acid on leptin secretion and expression in primary cultured rat adipocytes. J. Physiol. Biochem. 2003, 59, 201-208.
39. Perez-Matute, P., Martinez, J. A., Marti, A., Moreno-Aliaga, M. J., Linoleic acid decreases leptin and adiponectin secretion from primary rat adipocytes in the presence of insulin. Lipids 2007, 42, 913-920.
40. Perez-Matute, P., Marti, A., Martinez, J. A., Fernandez-Otero, M. P. et al., Conjugated linoleic acid inhibits glucose metabolism, leptin and adiponectin secretion in primary cultured rat adipocytes. Mol. Cell. Endocrinol. 2007, 268, 50-58.
41. Wen, Y., Wang, H. W., Wu, J., Lu, H. L. et al., Effects of fatty acid regulation on visfatin gene expression in adipocytes. Chin. Med. J. (Engl.) 2006, 119, 1701-1708.