Anosognosia for memory impairment in Alzheimer's disease

Acta Neuropsychiatrica

Volumn 22, Issue 4, 2010, Pages 180-187

  Stewart, Georgina ^a   McGeown, William J ^a   Shanks, Michael F ^a   Venneri, Annalena ^a  

^a UNIVERSITY OF HULL   (United Kingdom)

Author keywords

awareness; dementia; insight; paired associated learning; questionnaire

Indexed keywords

ACCURACY; ADULT; AGED; ALZHEIMER DISEASE; AMNESIA; ANOSOGNOSIA; ARTICLE; AWARENESS; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; EPISODIC MEMORY; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; MALE; MENTAL PERFORMANCE; MENTAL TASK; NEUROLOGIC EXAMINATION; NEUROPSYCHOLOGICAL TEST; PREDICTION; SEMANTIC MEMORY; TASK PERFORMANCE;

EID: 77954358631     PISSN: 09242708     EISSN: 16015215     Source Type: Journal    
DOI: 10.1111/j.1601-5215.2010.00463.x     Document Type: Article

References (40)

1. McGlynn SM, Schacter DL. Unawareness of deficits in neuropsychological syndromes. J Clin Exp Neuropsychol 1989 11 : 143 205.
2. Migliorelli R, Teson A, Sabe L et al. Anosognosia in Alzheimer's disease: a study of associated factors. J Neuropsychiatry Clin Neurosci 1995 7 : 338 344.
3. Sevush S, Leve N. Denial of memory deficit in Alzheimer's disease. Am J Psychiatry 1993 150 : 748 751.
4. Bisiach E, Vallar G, Perani D et al. Unawareness of disease following lesions of the right hemisphere: anosognosia for hemiplegia and anosognosia for hemianopia. Neuropsychologia 1986 24 : 471 482.
5. Breier JI, Adair JC, Gold M et al. Dissociation of anosognosia for hemiplegia and aphasia during left-hemisphere anesthesia. Neurology 1995 45 : 65 67.
6. Jehkonen M, Ahonen JP, Dastidar P et al. Unawareness of deficits after right hemisphere stroke: double-dissociations of anosognosias. Acta Neurol Scand 2000 102 : 378 384.
7. Barrett AM, Eslinger PJ, Ballentine NH, Heilman KM. Unawareness of cognitive deficit (cognitive anosognosia) in probable AD and control subjects. Neurology 2005 64 : 693 699.
8. Moulin CJA, Perfect TJ, Jones R. Global predictions of memory in Alzheimer's disease: evidence for preserved metamemory monitoring. Aging Neuropsychol Cogn 2000 7 : 230 244. (Pubitemid 32102481)
9. Schacter DL. Toward a cognitive neuropsychology of awareness: implicit knowledge and anosognosia. J Clin Exp Neuropsychol 1990 12 : 155 178.
10. Agnew SK, Morris RG. The heterogeneity of anosognosia for memory impairment in Alzheimer's disease: a review of the literature and a proposed model. Aging Ment Health 1998 2 : 7 19.
11. Duke LM, Seltzer B, Seltzer JE, Vasterling JJ. Cognitive components of deficit awareness in Alzheimer's disease. Neuropsychology 2002 16 : 359 369.
12. Moulin CJ, Perfect TJ, Jones RW. Evidence for intact memory monitoring in Alzheimer's disease: metamemory sensitivity at encoding. Neuropsychologia 2000 38 : 1242 1250.
13. Moulin CJA, James N, Perfect TJ, Jones RW. Knowing what you cannot recognise: further evidence for intact metacognition in Alzheimer's disease. Aging Neuropsychol Cogn 2003 10 : 74 82.
14. Ansell EL, Bucks RS. Mnemonic anosognosia in Alzheimer's disease: a test of Agnew and Morris (1998). Neuropsychologia 2006 44 : 1095 1102.
15. Carlesimo GA, Sabbadini M, Fadda L, Caltagirone C. Forgetting from long-term memory in dementia and pure amnesia: role of task, delay of assessment and aetiology of cerebral damage. Cortex 1995 31 : 285 300.
16. Christensen H, Kopelman MD, Stanhope N et al. Rates of forgetting in Alzheimer dementia. Neuropsychologia 1998 36 : 547 557.
17. Isaac CL, Mayes AR. Rate of forgetting in amnesia: I. Recall and recognition of prose. J Exp Psychol Learn Mem Cogn 1999 25 : 942 962.
18. Isaac CL, Mayes AR. Rate of forgetting in amnesia: II. Recall and recognition of word lists at different levels of organization. J Exp Psychol Learn Mem Cogn 1999 25 : 963 977.
19. McKhann G, Drachman D, Folstein M et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984 34 : 939 944.
20. Hachinski VC, Iliff LD, Zilhka E et al. Cerebral blood flow in dementia. Arch Neurol 1975 32 : 632 637.
21. Brun A, Englund B, Gustafson L et al. Clinical and Neuropathological criteria for frontotemporal dementia. J Neurol Neurosurg Psychiatry 1994 57 : 416 418.
22. McKeith IG, Galasko D, Kosaka K et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology 1996 47 : 1113 1124.
23. Roman GC, Tatemichi TK, Erkinjuntti T et al. Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology 1993 43 : 250 260.
24. Wechsler D. Wechsler Memory Scale III.
25. Kashiwa Y, Kitabayashi Y, Narumoto J et al. Anosognosia in Alzheimer's disease: association with patient characteristics, psychiatric symptoms and cognitive deficits. Psychiatry Clin Neurosci 2005 59 : 697 704.
26. Starkstein SE, Jorge R, Mizrahi R, Robinson RG. A diagnostic formulation for anosognosia in Alzheimer's disease. J Neurol Neurosurg Psychiatry 2006 77 : 719 725.
27. Vogel A, Hasselbalch SG, Gade A et al. Cognitive and functional neuroimaging correlate for anosognosia in mild cognitive impairment and Alzheimer's disease. Int J Geriatr Psychiatry 2005 20 : 238 246.
28. Schneck MK, Reisberg B, Ferris SH. An overview of current concepts of Alzheimer's disease. Am J Psychiatry 1982 139 : 165 173.
29. Ecklund-Johnson E, Torres I. Unawareness of deficits in Alzheimer's disease and other dementias: operational definitions and empirical findings. Neuropsychol Rev 2005 15 : 147 166.
30. Conway MA, Pleydell-Pearce CW, Whitecross SE, Sharpe H. Brain imaging autobiographical memory. Psychol Lear Motiv 2002 41 : 229 264.
31. Westmacott R, Black SE, Freedman M, Moscovitch M. The contribution of autobiographical significance to semantic memory: evidence from Alzheimer's disease, semantic dementia, and amnesia. Neuropsychologia 2004 42 : 25 48.
32. Gosche KM, Mortimer JA, Smith CD et al. Hippocampal volume as an index of Alzheimer neuropathology: findings from the Nun Study. Neurology 2002 58 : 1476 1482.
33. Jack CR Jr, Petersen RC, Xu YC et al. Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease. Neurology 1997 49 : 786 794.
34. Kasniak AW, Zak MG. On the neuropsychology of metamemory: contributions from the study of amnesia and dementia. Learn Individ Dif 1996 8 : 355 381.
35. Vargha-Khadem F, Gadian DG, Watkins KE et al. Differential effects of early hippocampal pathology on episodic and semantic memory. Science 1997 277 : 376 380.
36. Venneri A, McGeown WJ, Hietanen HM et al. The anatomical bases of semantic retrieval deficits in early Alzheimer's disease. Neuropsychologia 2008 46 : 497 510.
37. Venneri A, Shanks MF. Belief and awareness: reflections on a case of persistent anosognosia. Neuropsychologia 2004 42 : 230 238.
38. Clare L, Markova I, Verhey F, Kenny G. Awareness in dementia: a review of assessment methods and measures. Aging Ment Health 2005 9 : 394 413.
39. Clare L, Wilson BA, Carter G et al. Awareness in early-stage Alzheimer's disease: relationship to outcome of cognitive rehabilitation. J Clin Exp Neuropsychol 2004 26 : 215 226. (Pubitemid 38429313)
40. Hirschman RS. Memory disorders in older adults. In: Blackwell B, ed. Treatment compliance and the therapeutic alliance.