Genetic analysis of expression profile involved in retinoid metabolism in non-alcoholic fatty liver disease

Hepatology Research

Volumn 40, Issue 6, 2010, Pages 594-604

  Ashla, An Afida ^a   Hoshikawa, Yoshiko ^a   Tsuchiya, Hiroyuki ^a   Hashiguchi, Koich ^a   Enjoji, Munechika ^b   Nakamuta, Makoto ^c   Taketomi, Akinobu ^d   Maehara, Yoshihiko ^d   Shomori, Kohei ^a   Kurimasa, Akihiro ^a   Hisatome, Ichiro ^a   Ito, Hisao ^a   Shiota, Goshi ^a  

^a TOTTORI UNIVERSITY   (Japan)

^b FUKUOKA UNIVERSITY   (Japan)

^c NATIONAL HOSPITAL ORGANIZATION   (Japan)

^d KYUSHU UNIVERSITY   (Japan)

Author keywords

Non alcoholic fatty liver disease; Oxidative stress; Retinoid metabolism; Retinoid target gene

Indexed keywords

CATALASE; REACTIVE OXYGEN METABOLITE; RETINOIC ACID; RETINOID; THIOREDOXIN; UNCOUPLING PROTEIN 2;

ADULT; ARTICLE; CES 1 GENE; CLINICAL ARTICLE; CONTROLLED STUDY; CRBP 1 GENE; DGT 1; DGT 2 GENE; DISEASE COURSE; FEMALE; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN; IMMUNOHISTOCHEMISTRY; LRAT GENE; MALE; NONALCOHOLIC FATTY LIVER; NUCLEOTIDE SEQUENCE; OXIDATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STEATOSIS;

EID: 77954358490     PISSN: 13866346     EISSN: 1872034X     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2010.00646.x     Document Type: Article

References (29)

1. Torres DM, Harrison SA. Diagnosis and therapy of nonalcoholic steatohepatitis. Gastroenteology 2008, 134:1682-98.
2. Ong JP, Younossi ZM. Epidemiology and natural history of NAFLD and NASH. Clin Liver Dis 2007, 11:1-16.
3. Sefaty L, Lemoine M. Definition and natural history of metabolic steatosis: clinical aspects of NAFLD, NASH and cirrhoss. Diabetes Metab 2008, 34:634-7.
4. Adams LA, Lymp JF, Sauver J. The natural history of nonalhoholic fatty liver disease: a population-based cohort study. Gastroenterology 2005, 129:113-21.
5. Hashimoto E, Yatsuji S, Tobari M. Hepatocellular carcinoma in patients with nonalcoholic staetohepatitis. J Gastroenterol 2009, 44:89-95.
6. Koike K. Molecular basis of hepatitis C virus-associated hepatocarcinogenesis: lessons from animal model studies. Clin Gastroenterol Hepatol 2005, 3:S132-135.
7. Marra F, Gastaldelli A, Baroni GS. Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis. Trends Mol Med 2004, 14:72-81.
8. Mongan NP, Gudas LJ. Diverse actions of retinoid receptors in cancer prevention and treatment. Differentaition 2007, 75:853-70.
9. Reeves HL, Friedman SL. Activation of hepatic stellate cells-a key issue in liver fibrosis. Front Biosci 2002, 7:d808-26.
10. Saitou M, Naruyama S, Kakizuka A. Alteration of a single amino acid residue in retinoic acid receptor causes dominant\-negative phenotype. J Biol Chem 1994, 269:19101-7.
11. Yanagidani A, Yamada S, Yasui S. Retinoic acid recptor α dominant negative form causes steatohepatitis and liver tumors in transgenic mice. Hepatology 2004, 40:366-75.
12. Tsuchiya H, Akechi Y, Ikeda R. Suppressive effects of retinoids on iron-induced oxidative stress in the liver. Gastroenterology 2009, 136:341-50.
13. Yuan JM, Gao YT, Ong CN, Ross RK, Yu MC. Prediagnostic level of serum retinol in relation to reduced risk of hepatocellular carcinoma. J Natl Cancer Inst 2006, 98:482-90.
14. Muto Y, Moriwaki H, Ninomiya M. Prevention of second primary tumors by an acyclic retinoid, polyprenoic acid, in patients with hepatocellular carcinoma. N Engl J Med 1996, 334:1561-7.
15. Matteoni CA, Younossi ZM, Gramlich T. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterlogy 1999, 116:1413-19.
16. Schug TT, Berry DC, Shaw NS, Travis SN, Noy N. Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors. Cell 2007, 129:723-33.
17. Eisinger AL, Nadauld LD, Shelton DN. The adenomatous polyposis coli tumor suppressor gene regulates expression of cyclooxygenase-2 by a mechanism that involves retinoic acid. J Biol Chem 2006, 281:20474-82.
18. Blomhoff R, Blomhoff HK. Overview of retinoid mtabolism and function. J Neurobiol 2006, 66:606-30.
19. Yamaguchi K, McCall S, Huang J. Diacylglycerol acytransferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis. Hepatology 2008, 47:625-35.
20. Sanghani SP, Davis WI, Dumaual NG. Identification of microsomal rat liver carboxyesterases and their activity with retinyl palmitate. Eur J Biochem 2002, 269:4387-98.
21. Dong D, Ruuska SE, Levinthal DJ. Distinct roles for cellular retinol acid-binding proteins I and II in regulating signaling by retinoica cid. J Biol Chem 1999, 274:23695-8.
22. Boylan JF, Gudas LJ. The level of CRABP-I expression influences the amounts and types of all-trans-retinoic acid metabolites in F9 tetracarcinoma stem cells. J Biol Chem 1992, 67:21486-91.
23. Natarajan SK, Amirtharaj GJ, Ramachandran A, Pulimood AB, Balasubramanian KA. Retinoid metabolism in the small intestine during development of liver cirrhosis. J Gastroenterol Hepatol 2009, 24:821-9.
24. Bell H, Nilsson A, Norum KR, Pedersen LB, Raknerud N, Rasmussen M. Retinol and retinyl esters in patients with alcoholic liver disease. J Hepatol 1989, 8:26-31.
25. Kanematsu T, Kawano T, Sugimachi K. Blood concentrations of thirteen vitamins in cirrhotic patients. Nutrition 1989, 5:179-82.
26. Fujita N, Miyachi H, Tanaka H. Iron overload is associated with hepatic oxidative damage to DNA in nonalcoholic steatohepatitis. Cancer Epidemol Biomarkers Prev 2009, 18:424-32.
27. Ghyselinck NB, Bavik C, Sapin V. Cellular retinol-binding protein I is essential for vitamin A homeostasis. EMBO J 1999, 18:4903-14.
28. Batten MI, Imanishi Y, Meada T. Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver. J Biol Chem 2004, 279:10422-32.
29. Carpino G, Morini S, Ginanni CS. Alpha-SMA expression in hepatic stellate cells and quantitative analysis of hepatic fibrosis in cirrhosis and in recurrent chronic hepatitis after liver transplantation. Dig Liver Dis 2005, 37:349-56.