N, N-dimethylbiguanide complexes displaying low cytotoxicity as potential large spectrum antimicrobial agents

European Journal of Medicinal Chemistry

Volumn 45, Issue 7, 2010, Pages 3027-3034

  Olar, Rodica ^a   Badea, Mihaela ^a   Marinescu, Dana ^a   Chifiriuc, Mariana Carmen ^a   Bleotu, Coralia ^b   Grecu, Maria Nicoleta ^c   Iorgulescu, Emilia Elena ^a   Lazar, Veronica ^a  

^a UNIVERSITY OF BUCHAREST   (Romania)

^b STEFAN S NICOLAU INSTITUTE OF VIROLOGY   (Romania)

^c NATIONAL INSTITUTE OF MATERIALS PHYSICS   (Romania)

Author keywords

Antimicrobial activity; Bacterial biofilm; Complex; Cytotoxicity; N,N dimethylbiguanide

Indexed keywords

ANTIINFECTIVE AGENT; BIGUANIDE DERIVATIVE;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIUM COLONY; CARBON NUCLEAR MAGNETIC RESONANCE; CYCLIC POTENTIOMETRY; CYTOTOXICITY; DRUG ACTIVITY; DRUG SYNTHESIS; ELECTRON SPIN RESONANCE; HELA CELL; HUMAN; HUMAN CELL; INFRARED SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA; REDOX STRESS; STAPHYLOCOCCUS AUREUS;

EID: 77954349758     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.03.033     Document Type: Article

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