Prospects for new antimicrobials based on N,N-dimethylbiguanide complexes as effective agents on both planktonic and adhered microbial strains

European Journal of Medicinal Chemistry

Volumn 45, Issue 7, 2010, Pages 2868-2875

  Olar, Rodica ^a   Badea, Mihaela ^a   Marinescu, Dana ^a   Chifiriuc, Carmen Mariana ^a   Bleotu, Coralia ^b   Grecu, Maria Nicoleta ^c   Iorgulescu, Emilia Elena ^a   Bucur, Marcela ^b   Lazar, Veronica ^a   Finaru, Adriana ^d  

^a UNIVERSITY OF BUCHAREST   (Romania)

^b STEFAN S NICOLAU INSTITUTE OF VIROLOGY   (Romania)

^c NATIONAL INSTITUTE OF MATERIALS PHYSICS   (Romania)

^d Vasile Alecsandri University   (Romania)

Author keywords

Antimicrobial activity; Complex; Cytotoxicity; Microbial biofilm; N,N dimethylbiguanide

Indexed keywords

BIGUANIDE DERIVATIVE;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BACTERIAL STRAIN; CANDIDA ALBICANS; CELL CYCLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYCLIC POTENTIOMETRY; CYTOTOXICITY; ELECTRON SPIN RESONANCE; ESCHERICHIA COLI; EUKARYOTIC CELL; FUNGAL STRAIN; HELA CELL; HUMAN; HUMAN CELL; INFRARED SPECTROMETRY; KLEBSIELLA PNEUMONIAE; LISTERIA MONOCYTOGENES; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION REDUCTION REACTION; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; ULTRAVIOLET SPECTROSCOPY;

ANTI-INFECTIVE AGENTS; BACTERIA; BACTERIAL ADHESION; BIOFILMS; CRYSTALLOGRAPHY, X-RAY; ELECTROCHEMISTRY; FUNGI; HELA CELLS; HUMANS; MAGNETICS; METFORMIN; OXIDATION-REDUCTION; PLANKTON; SPECTRUM ANALYSIS;

EID: 77954348554     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.03.009     Document Type: Article

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