메뉴 건너뛰기




Volumn 49, Issue 1, 2010, Pages 14-22

Melatonin and circadian biology in human cardiovascular disease

Author keywords

cardiovascular disease; cardiovascular system; circadian rhythm; heart; melatonin

Indexed keywords

BIOLOGICAL MARKER; MELATONIN; NEUROHORMONE;

EID: 77954336406     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2010.00773.x     Document Type: Review
Times cited : (206)

References (136)
  • 1
    • 0025993870 scopus 로고
    • Circadian variation and cardiovascular disease
    • Muller JE, Tofler GH. Circadian variation and cardiovascular disease. N Engl J Med 1991 325 : 1038 1039.
    • (1991) N Engl J Med , vol.325 , pp. 1038-1039
    • Muller, J.E.1    Tofler, G.H.2
  • 2
    • 0026780187 scopus 로고
    • Increased onset of sudden cardiac death in the first three hours after awakening
    • Willich SN, Goldberg RJ, Maclure M et al. Increased onset of sudden cardiac death in the first three hours after awakening. Am J Cardiol 1992 70 : 65 68.
    • (1992) Am J Cardiol , vol.70 , pp. 65-68
    • Willich, S.N.1    Goldberg, R.J.2    MacLure, M.3
  • 3
    • 0035934593 scopus 로고    scopus 로고
    • Health in a 24-h society
    • Rajaratnam SM, Arendt J. Health in a 24-h society. Lancet 2001 358 : 999 1005.
    • (2001) Lancet , vol.358 , pp. 999-1005
    • Rajaratnam, S.M.1    Arendt, J.2
  • 4
    • 0037352799 scopus 로고    scopus 로고
    • Health disorders of shift workers
    • Knutsson A. Health disorders of shift workers. Occup Med (Lond) 2003 53 : 103 108.
    • (2003) Occup Med (Lond) , vol.53 , pp. 103-108
    • Knutsson, A.1
  • 5
    • 34547541570 scopus 로고    scopus 로고
    • Potential role for peripheral circadian clock dyssynchrony in the pathogenesis of cardiovascular dysfunction
    • Young ME, Bray MS. Potential role for peripheral circadian clock dyssynchrony in the pathogenesis of cardiovascular dysfunction. Sleep Med 2007 8 : 656 667.
    • (2007) Sleep Med , vol.8 , pp. 656-667
    • Young, M.E.1    Bray, M.S.2
  • 6
    • 33644793780 scopus 로고    scopus 로고
    • The circadian clock within the heart: Potential influence on myocardial gene expression, metabolism, and function
    • Young ME. The circadian clock within the heart: potential influence on myocardial gene expression, metabolism, and function. Am J Physiol Heart Circ Physiol 2006 290 : H1 H16.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Young, M.E.1
  • 8
    • 0033637383 scopus 로고    scopus 로고
    • Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus
    • Damiola F, Le Minh N, Preitner N et al. Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus. Genes Dev 2000 14 : 2950 2961.
    • (2000) Genes Dev , vol.14 , pp. 2950-2961
    • Damiola, F.1    Le Minh, N.2    Preitner, N.3
  • 9
    • 0036264490 scopus 로고    scopus 로고
    • Metabolism and the cardiovascular system
    • Sewerynek E. Metabolism and the cardiovascular system. Neuro Endocrinol Lett 2002 23 : 79 83.
    • (2002) Neuro Endocrinol Lett , vol.23 , pp. 79-83
    • Sewerynek, E.1
  • 10
    • 0033006886 scopus 로고    scopus 로고
    • Circadian variation in cardiovascular events
    • Muller JE. Circadian variation in cardiovascular events. Am J Hypertens 1999 12 : 35S 42S.
    • (1999) Am J Hypertens , vol.12
    • Muller, J.E.1
  • 12
    • 33644878789 scopus 로고    scopus 로고
    • Circadian variations in stroke-a prospective-hospital-based study
    • Gupta A, Shetty H. Circadian variations in stroke-a prospective-hospital- based study. Int J Clin Pract 2005 59 : 1272 1275.
    • (2005) Int J Clin Pract , vol.59 , pp. 1272-1275
    • Gupta, A.1    Shetty, H.2
  • 13
    • 0028120681 scopus 로고
    • Twenty-four-hour blood pressure and heart rate profiles in humans. A twin study
    • Degaute JP, Van Cauter E, Van De Borne P, Linkowski P. Twenty-four-hour blood pressure and heart rate profiles in humans. A twin study. Hypertension 1994 23 : 244 253.
    • (1994) Hypertension , vol.23 , pp. 244-253
    • Degaute, J.P.1    Van Cauter, E.2    Van De Borne, P.3    Linkowski, P.4
  • 14
    • 1842479160 scopus 로고    scopus 로고
    • Gene- and tissue-specific alterations of circadian clock gene expression in streptozotocin-induced diabetic mice under restricted feeding
    • Oishi K, Kasamatsu M, Ishida N. Gene- and tissue-specific alterations of circadian clock gene expression in streptozotocin-induced diabetic mice under restricted feeding. Biochem Biophys Res Commun 2004 317 : 330 334.
    • (2004) Biochem Biophys Res Commun , vol.317 , pp. 330-334
    • Oishi, K.1    Kasamatsu, M.2    Ishida, N.3
  • 16
    • 0033398067 scopus 로고    scopus 로고
    • Towards the 24-hour society-New approaches for aging shift workers?
    • Harma MI, Ilmarinen JE. Towards the 24-hour society-New approaches for aging shift workers?. Scand J Work Environ Health 1999 25 : 610 615.
    • (1999) Scand J Work Environ Health , vol.25 , pp. 610-615
    • Harma, M.I.1    Ilmarinen, J.E.2
  • 17
    • 0022655459 scopus 로고
    • Increased risk of ischaemic heart disease in shift workers
    • Knutsson A, Akerstedt T, Jonsson BG, Orth-Gomer K. Increased risk of ischaemic heart disease in shift workers. Lancet 1986 12 : 89 92.
    • (1986) Lancet , vol.12 , pp. 89-92
    • Knutsson, A.1    Akerstedt, T.2    Jonsson, B.G.3    Orth-Gomer, K.4
  • 18
    • 0021041759 scopus 로고
    • Health risks related to shift work. An example of time-contingent effects of long-term stress
    • Koller M. Health risks related to shift work. An example of time-contingent effects of long-term stress. Int Arch Occup Environ Health 1983 53 : 59 75.
    • (1983) Int Arch Occup Environ Health , vol.53 , pp. 59-75
    • Koller, M.1
  • 19
    • 0026306221 scopus 로고
    • Circadian variation of myocardial ischemia in patients with stable coronary artery disease
    • Hausmann D, Lichtlen PR, Nikutta P, Wenzlaff P et al. Circadian variation of myocardial ischemia in patients with stable coronary artery disease. Chronobiol Int 1991 8 : 385 398.
    • (1991) Chronobiol Int , vol.8 , pp. 385-398
    • Hausmann, D.1    Lichtlen, P.R.2    Nikutta, P.3    Wenzlaff, P.4
  • 20
    • 0025074037 scopus 로고
    • Circadian variation of acute myocardial infarction and the effect of low-dose aspirin in a randomized trial of physicians
    • Ridker PM, Manson JE, Buring JE et al. Circadian variation of acute myocardial infarction and the effect of low-dose aspirin in a randomized trial of physicians. Circulation 1990 82 : 897 902.
    • (1990) Circulation , vol.82 , pp. 897-902
    • Ridker, P.M.1    Manson, J.E.2    Buring, J.E.3
  • 21
    • 0023280646 scopus 로고
    • Circadian variation of cardiovascular disease and sympathetic activity
    • Muller JE, Tofler GH, Willich SN, Stone PH. Circadian variation of cardiovascular disease and sympathetic activity. J Cardiovasc Pharmacol 1987 10 (Suppl 2 S104 S109.
    • (1987) J Cardiovasc Pharmacol , vol.10 , Issue.SUPPL. 2
    • Muller, J.E.1    Tofler, G.H.2    Willich, S.N.3    Stone, P.H.4
  • 22
    • 0031574324 scopus 로고    scopus 로고
    • Chronobiological patterns of onset of acute cerebrovascular diseases
    • Manfredini R, Gallerani M, Portaluppi F, Salmi R et al. Chronobiological patterns of onset of acute cerebrovascular diseases. Thromb Res 1997 88 : 451 463.
    • (1997) Thromb Res , vol.88 , pp. 451-463
    • Manfredini, R.1    Gallerani, M.2    Portaluppi, F.3    Salmi, R.4
  • 23
    • 0027240973 scopus 로고
    • Chronobiological aspects of acute cerebrovascular diseases
    • Gallerani M, Manfredini R, Ricci L et al. Chronobiological aspects of acute cerebrovascular diseases. Acta Neurol Scand 1993 87 : 482 487.
    • (1993) Acta Neurol Scand , vol.87 , pp. 482-487
    • Gallerani, M.1    Manfredini, R.2    Ricci, L.3
  • 24
    • 0022384056 scopus 로고
    • Circadian variation in the frequency on onset of acute myocardial infarction
    • Muller JE, Stone PH, Turi ZG et al. Circadian variation in the frequency on onset of acute myocardial infarction. N Engl J Med 1985 313 : 1315 1322.
    • (1985) N Engl J Med , vol.313 , pp. 1315-1322
    • Muller, J.E.1    Stone, P.H.2    Turi, Z.G.3
  • 25
    • 0025375179 scopus 로고
    • Travel, time zones, and sudden cardiac death. Emporiatric pathology
    • Couch RD. Travel, time zones, and sudden cardiac death. Emporiatric pathology. Am J Forensic Med Pathol 1990 11 : 106 111.
    • (1990) Am J Forensic Med Pathol , vol.11 , pp. 106-111
    • Couch, R.D.1
  • 26
    • 0029982023 scopus 로고    scopus 로고
    • Circadian variation of ambulatory myocardial ischemia. Triggering by daily activities and evidence for an endogenous circadian component
    • Krantz DS, Kop WJ, Gabbay FH et al. Circadian variation of ambulatory myocardial ischemia. Triggering by daily activities and evidence for an endogenous circadian component. Circulation 1996 93 : 1364 1371.
    • (1996) Circulation , vol.93 , pp. 1364-1371
    • Krantz, D.S.1    Kop, W.J.2    Gabbay, F.H.3
  • 27
    • 11144233793 scopus 로고    scopus 로고
    • Endogenous circadian rhythm in an index of cardiac vulnerability independent of changes in behavior
    • Hu K, Ivanov P, Hilton MF et al. Endogenous circadian rhythm in an index of cardiac vulnerability independent of changes in behavior. Proc Natl Acad Sci USA 2004 101 : 18223 18227.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 18223-18227
    • Hu, K.1    Ivanov, P.2    Hilton, M.F.3
  • 28
    • 23744468285 scopus 로고    scopus 로고
    • Circadian variation in stroke onset: Identical temporal pattern in ischemic and hemorrhagic events
    • Manfredini R, Boari B, Smolensky MH et al. Circadian variation in stroke onset: identical temporal pattern in ischemic and hemorrhagic events. Chronobiol Int 2005 22 : 417 453.
    • (2005) Chronobiol Int , vol.22 , pp. 417-453
    • Manfredini, R.1    Boari, B.2    Smolensky, M.H.3
  • 29
    • 47349106112 scopus 로고    scopus 로고
    • Day-night variation of acute myocardial infarction in obstructive sep apnea
    • Kuniyoshi FH, Garcia-Touchard A, Gami AS et al. Day-night variation of acute myocardial infarction in obstructive sep apnea. J Am Coll Cardiol 2008 52 : 343 346.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 343-346
    • Kuniyoshi, F.H.1    Garcia-Touchard, A.2    Gami, A.S.3
  • 31
    • 77949267538 scopus 로고    scopus 로고
    • Effect of circadian system and behavioral stressors on platelet activity and reactivity: Implications for the morning peak in cardiovascular incidents
    • Scheer FA, Evoniuk H, Kelly E et al. Effect of circadian system and behavioral stressors on platelet activity and reactivity: implications for the morning peak in cardiovascular incidents. Sleep 2009 32 : A7.
    • (2009) Sleep , vol.32 , pp. 7
    • Scheer, F.A.1    Evoniuk, H.2    Kelly, E.3
  • 32
    • 0023789514 scopus 로고
    • Association with assumption of the upright posture
    • Brezinski DA, Tofler GH, Muller JE et al. Association with assumption of the upright posture. Circulation 1988 78 : 35 40.
    • (1988) Circulation , vol.78 , pp. 35-40
    • Brezinski, D.A.1    Tofler, G.H.2    Muller, J.E.3
  • 33
    • 0035827721 scopus 로고    scopus 로고
    • Clock genes in the heart: Characterization and attenuation with hypertrophy
    • Young ME, Razeghi P, Taegtmeyer H. Clock genes in the heart: characterization and attenuation with hypertrophy. Circ Res 2001 88 : 1142 1150.
    • (2001) Circ Res , vol.88 , pp. 1142-1150
    • Young, M.E.1    Razeghi, P.2    Taegtmeyer, H.3
  • 34
    • 27444437395 scopus 로고    scopus 로고
    • Bioinformatic analysis of circadian gene oscillation in mouse aorta
    • Rudic RD, Mcnamara P, Reilly D et al. Bioinformatic analysis of circadian gene oscillation in mouse aorta. Circulation 2005 112 : 2716 2724.
    • (2005) Circulation , vol.112 , pp. 2716-2724
    • Rudic, R.D.1    McNamara, P.2    Reilly, D.3
  • 35
    • 33847669725 scopus 로고    scopus 로고
    • Circadian variation of blood pressure and the vascular response to asynchronous stress
    • Curtis AM, Cheng Y, Kapoor S et al. Circadian variation of blood pressure and the vascular response to asynchronous stress. Proc Natl Acad Sci USA 2007 104 : 3450 3455.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 3450-3455
    • Curtis, A.M.1    Cheng, Y.2    Kapoor, S.3
  • 36
    • 34247535799 scopus 로고    scopus 로고
    • Mutation of the circadian clock gene Per2 alters vascular endothelial function
    • Viswambharan H, Carvas JM, Antic V et al. Mutation of the circadian clock gene Per2 alters vascular endothelial function. Circulation 2007 115 : 2188 2195.
    • (2007) Circulation , vol.115 , pp. 2188-2195
    • Viswambharan, H.1    Carvas, J.M.2    Antic, V.3
  • 37
    • 0017527971 scopus 로고    scopus 로고
    • Synthesis of prostaglandin I2 (prostacyclin) by cultured human and bovine endothelial cells
    • Weksler BB, Marcus AJ, Jaffe EA. Synthesis of prostaglandin I2 (prostacyclin) by cultured human and bovine endothelial cells. Proc Natl Acad Sci USA 1997 74 : 3922 3926.
    • (1997) Proc Natl Acad Sci USA , vol.74 , pp. 3922-3926
    • Weksler, B.B.1    Marcus, A.J.2    Jaffe, E.A.3
  • 39
    • 0025162134 scopus 로고
    • Endothelial control of vascular tone in large and small coronary arteries
    • Luscher TF, Richard V, Tschudi M et al. Endothelial control of vascular tone in large and small coronary arteries. J Am Coll Cardiol 1990 15 : 519 527.
    • (1990) J Am Coll Cardiol , vol.15 , pp. 519-527
    • Luscher, T.F.1    Richard, V.2    Tschudi, M.3
  • 40
    • 0001599370 scopus 로고
    • Role of endothelium-derived nitric oxide in the regulation of blood pressure
    • Rees DD, Palmer RM, Moncada S. Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc Natl Acad Sci USA 1989 86 : 3375 3378.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 3375-3378
    • Rees, D.D.1    Palmer, R.M.2    Moncada, S.3
  • 41
    • 0036264722 scopus 로고    scopus 로고
    • Circadian variation in vascular tone and endothelial cell function in normal males
    • Elherik K, Khan F, Mclaren M et al. Circadian variation in vascular tone and endothelial cell function in normal males. Clin Sci (Lond) 2002 102 : 547 552.
    • (2002) Clin Sci (Lond) , vol.102 , pp. 547-552
    • Elherik, K.1    Khan, F.2    McLaren, M.3
  • 42
    • 2642537650 scopus 로고    scopus 로고
    • Early morning attenuation of endothelial function in healthy humans
    • Otto ME, Svatikova A, Barretto RB et al. Early morning attenuation of endothelial function in healthy humans. Circulation 2004 109 : 2507 2510.
    • (2004) Circulation , vol.109 , pp. 2507-2510
    • Otto, M.E.1    Svatikova, A.2    Barretto, R.B.3
  • 43
    • 0026179469 scopus 로고
    • Circadian variation of endothelial cell function, red blood cell deformability and dehydro-thromboxane B2 in healthy volunteers
    • Bridges AB, Mclaren M, Saniabadi A et al. Circadian variation of endothelial cell function, red blood cell deformability and dehydro-thromboxane B2 in healthy volunteers. Blood Coagul Fibrinolysis 1991 2 : 447 452.
    • (1991) Blood Coagul Fibrinolysis , vol.2 , pp. 447-452
    • Bridges, A.B.1    McLaren, M.2    Saniabadi, A.3
  • 44
    • 0032932092 scopus 로고    scopus 로고
    • Circadian variation and triggering of acute coronary events
    • Muller JE. Circadian variation and triggering of acute coronary events. Am Heart J 1999 137 : S1 S8.
    • (1999) Am Heart J , vol.137
    • Muller, J.E.1
  • 45
    • 14644397985 scopus 로고    scopus 로고
    • Daily and circadian rhythms of tissue factor pathway inhibitor and factor VII activity
    • Pinotti M, Bertolucci C, Portaluppi F et al. Daily and circadian rhythms of tissue factor pathway inhibitor and factor VII activity. Arterioscler Thromb Vasc Biol 2005 25 : 646 649.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 646-649
    • Pinotti, M.1    Bertolucci, C.2    Portaluppi, F.3
  • 46
    • 0034775713 scopus 로고    scopus 로고
    • Day-night variations in blood levels of nitric oxide, T-TFPI, and E-selectin
    • Kanabrocki EL, George M, Hermida RC et al. Day-night variations in blood levels of nitric oxide, T-TFPI, and E-selectin. Clin Appl Thromb Hemost 2001 7 : 339 345.
    • (2001) Clin Appl Thromb Hemost , vol.7 , pp. 339-345
    • Kanabrocki, E.L.1    George, M.2    Hermida, R.C.3
  • 47
    • 0024835299 scopus 로고
    • Circadian rhythms of blood clotting time an coagulation factors II, VII, IX and X in rats
    • Soulban G, Labrecque G. Circadian rhythms of blood clotting time an coagulation factors II, VII, IX and X in rats. Life Sci 1989 45 : 2485 2489.
    • (1989) Life Sci , vol.45 , pp. 2485-2489
    • Soulban, G.1    Labrecque, G.2
  • 48
    • 0033977130 scopus 로고    scopus 로고
    • Relation between circadian patterns in levels of circulating lipoprotein(a), fibrinogen, platelets, and related lipid variables in men
    • Brenner WF, Sothern RB, Kanabrocki EL et al. Relation between circadian patterns in levels of circulating lipoprotein(a), fibrinogen, platelets, and related lipid variables in men. Am Heart J 2000 139 : 164 173.
    • (2000) Am Heart J , vol.139 , pp. 164-173
    • Brenner, W.F.1    Sothern, R.B.2    Kanabrocki, E.L.3
  • 49
    • 62449319038 scopus 로고    scopus 로고
    • Defining chronodisruption
    • Erren TC, Reiter RJ. Defining chronodisruption. J Pineal Res 2009 46 : 245 247.
    • (2009) J Pineal Res , vol.46 , pp. 245-247
    • Erren, T.C.1    Reiter, R.J.2
  • 50
    • 68649085172 scopus 로고    scopus 로고
    • Cardiac autonomic neuropathy, estimated cardio-vascular risk, and circadian blood pressure pattern in diabetes mellitus
    • Cabezas-Cerrato J, Hermida RC, Cabezas-Agricola JM, Ayala DE. Cardiac autonomic neuropathy, estimated cardio-vascular risk, and circadian blood pressure pattern in diabetes mellitus. Chronobiol Int 2009 26 : 942 957.
    • (2009) Chronobiol Int , vol.26 , pp. 942-957
    • Cabezas-Cerrato, J.1    Hermida, R.C.2    Cabezas-Agricola, J.M.3    Ayala, D.E.4
  • 51
  • 53
    • 0025758136 scopus 로고
    • Pineal melatonin: Cell biology of its synthesis and its physiological interactions
    • Reiter RJ. Pineal melatonin: cell biology of its synthesis and its physiological interactions. Endocr Rev 1991 12 : 151 180.
    • (1991) Endocr Rev , vol.12 , pp. 151-180
    • Reiter, R.J.1
  • 54
    • 0027210003 scopus 로고
    • The melatonin rhythm: Both a clock and a calendar
    • Reiter RJ. The melatonin rhythm: both a clock and a calendar. Experientia 1993 49 : 654 664.
    • (1993) Experientia , vol.49 , pp. 654-664
    • Reiter, R.J.1
  • 55
    • 0019209714 scopus 로고
    • Pineal melatonin rhythm: Reduction in aging Syrian hamsters
    • Reiter RJ, Richardson BA, Johnson LY. Pineal melatonin rhythm: reduction in aging Syrian hamsters. Science 1980 210 : 1372 1373.
    • (1980) Science , vol.210 , pp. 1372-1373
    • Reiter, R.J.1    Richardson, B.A.2    Johnson, L.Y.3
  • 56
    • 0019405864 scopus 로고
    • Age-associated reduction in nocturnal pineal melatonin levels in female rats
    • Reiter RJ, Craft CM, Johnson JEJR et al. Age-associated reduction in nocturnal pineal melatonin levels in female rats. Endocrinology 1981 109 : 1295 1297.
    • (1981) Endocrinology , vol.109 , pp. 1295-1297
    • Reiter, R.J.1    Craft, C.M.2    Jejr, J.3
  • 57
    • 0022973346 scopus 로고
    • Human melatonin production decreases with age
    • Sack RL, Lewy AJ, Erb DL et al. Human melatonin production decreases with age. J Pineal Res 1986 3 : 379 388.
    • (1986) J Pineal Res , vol.3 , pp. 379-388
    • Sack, R.L.1    Lewy, A.J.2    Erb, D.L.3
  • 58
    • 0032871506 scopus 로고    scopus 로고
    • Decreased melatonin synthesis in patients with coronary artery disease
    • Sakotnik A, Liebmann PM, Stoschitzky K et al. Decreased melatonin synthesis in patients with coronary artery disease. Eur Heart J 1999 20 : 1314 1317.
    • (1999) Eur Heart J , vol.20 , pp. 1314-1317
    • Sakotnik, A.1    Liebmann, P.M.2    Stoschitzky, K.3
  • 59
    • 0037135288 scopus 로고    scopus 로고
    • Impaired nocturnal synthesis of melatonin in patients with cardiac syndrome X
    • Altun A, Yaprak M, Aktoz M et al. Impaired nocturnal synthesis of melatonin in patients with cardiac syndrome X. Neurosci Lett 2002 327 : 143 145.
    • (2002) Neurosci Lett , vol.327 , pp. 143-145
    • Altun, A.1    Yaprak, M.2    Aktoz, M.3
  • 60
    • 0036829421 scopus 로고    scopus 로고
    • Decreased nocturnal melatonin levels during acute myocardial infarction
    • Dominguez-Rodriguez A, Abreu-Gonzalez P, Garcia MJ et al. Decreased nocturnal melatonin levels during acute myocardial infarction. J Pineal Res 2002 33 : 248 252.
    • (2002) J Pineal Res , vol.33 , pp. 248-252
    • Dominguez-Rodriguez, A.1    Abreu-Gonzalez, P.2    Garcia, M.J.3
  • 61
    • 0242548489 scopus 로고    scopus 로고
    • Decreased nocturnal synthesis of melatonin in patients with coronary artery disease
    • Yaprak M, Altun A, Vardar A et al. Decreased nocturnal synthesis of melatonin in patients with coronary artery disease. Int J Cardiol 2003 89 : 103 107.
    • (2003) Int J Cardiol , vol.89 , pp. 103-107
    • Yaprak, M.1    Altun, A.2    Vardar, A.3
  • 62
    • 36849008650 scopus 로고    scopus 로고
    • Cardiovascular diseases: Protective effects of melatonin
    • Tengattini S, Reiter RJ, Tan DX et al. Cardiovascular diseases: protective effects of melatonin. J Pineal Res 2008 44 : 16 25.
    • (2008) J Pineal Res , vol.44 , pp. 16-25
    • Tengattini, S.1    Reiter, R.J.2    Tan, D.X.3
  • 64
    • 0031242825 scopus 로고    scopus 로고
    • The effect of atenolol, a β1-adrenergic antagonist, on nocturnal plasma melatonin secretion: Evidence for a dose-response relationship in humans
    • Nathan PJ, Maguire KP, Burrows GD, Norman TR. The effect of atenolol, a β1-adrenergic antagonist, on nocturnal plasma melatonin secretion: evidence for a dose-response relationship in humans. J Pineal Res 1997 23 : 131 135.
    • (1997) J Pineal Res , vol.23 , pp. 131-135
    • Nathan, P.J.1    Maguire, K.P.2    Burrows, G.D.3    Norman, T.R.4
  • 65
    • 0033814953 scopus 로고    scopus 로고
    • Low urinary 6-sulphatoxymelatonin levels in patients with coronary artery disease
    • Girotti L, Lago M, Ianavsky O et al. Low urinary 6-sulphatoxymelatonin levels in patients with coronary artery disease. J Pineal Res 2000 29 : 138 142.
    • (2000) J Pineal Res , vol.29 , pp. 138-142
    • Girotti, L.1    Lago, M.2    Ianavsky, O.3
  • 66
    • 67651151194 scopus 로고    scopus 로고
    • Physiology and pharmacology of melatonin in relation to biological rhythms
    • Zawilska JB, Skene DJ, Arendt J. Physiology and pharmacology of melatonin in relation to biological rhythms. Pharmacol Rep 2009 61 : 383 410.
    • (2009) Pharmacol Rep , vol.61 , pp. 383-410
    • Zawilska, J.B.1    Skene, D.J.2    Arendt, J.3
  • 67
    • 67649998213 scopus 로고    scopus 로고
    • Long-term follow-up of melatonin treatment in children with ADHD and chronic sleep onset insomnia
    • Hoebert M, Van Der Heijden KB, Van Geijlswijk IM, Smits MG. Long-term follow-up of melatonin treatment in children with ADHD and chronic sleep onset insomnia. J Pineal Res 2009 47 : 1 7.
    • (2009) J Pineal Res , vol.47 , pp. 1-7
    • Hoebert, M.1    Van Der Heijden, K.B.2    Van Geijlswijk, I.M.3    Smits, M.G.4
  • 68
    • 0035960605 scopus 로고    scopus 로고
    • Oxidant stress as marker for cardiovascular events: Ox marks the spot
    • Landmesser U, Harrison DG. Oxidant stress as marker for cardiovascular events: Ox marks the spot. Circulation 2001 104 : 2638 2640.
    • (2001) Circulation , vol.104 , pp. 2638-2640
    • Landmesser, U.1    Harrison, D.G.2
  • 69
    • 0027989308 scopus 로고
    • Melatonin inhibits LDL receptor activity and cholesterol synthesis in freshly isolated human mononuclear leukocytes
    • Muller-Wieland D, Behnke B, Koopmann K, Krone W. Melatonin inhibits LDL receptor activity and cholesterol synthesis in freshly isolated human mononuclear leukocytes. Biochem Biophys Res Commun 1994 203 : 416 421.
    • (1994) Biochem Biophys Res Commun , vol.203 , pp. 416-421
    • Muller-Wieland, D.1    Behnke, B.2    Koopmann, K.3    Krone, W.4
  • 70
    • 0031133777 scopus 로고    scopus 로고
    • Melatonin inhibits oxidative modification of human low-density lipoprotein
    • Kelly MR, Loo G. Melatonin inhibits oxidative modification of human low-density lipoprotein. J Pineal Res 1997 22 : 203 209.
    • (1997) J Pineal Res , vol.22 , pp. 203-209
    • Kelly, M.R.1    Loo, G.2
  • 71
    • 0030882965 scopus 로고    scopus 로고
    • Effect of melatonin and metabolites on cooper-mediated oxidation of low density lipoprotein
    • Seegar H, Mueck AO, Lippert TH. Effect of melatonin and metabolites on cooper-mediated oxidation of low density lipoprotein. Br J Clin Pharmacol 1997 44 : 283 284.
    • (1997) Br J Clin Pharmacol , vol.44 , pp. 283-284
    • Seegar, H.1    Mueck, A.O.2    Lippert, T.H.3
  • 72
    • 0034068733 scopus 로고    scopus 로고
    • Serum cholesterol and lipid peroxidation are decreased by melatonin in diet-induced hypercholesterolemic rats
    • Hoyos M, Guerrero JM, Perez-Cano R et al. Serum cholesterol and lipid peroxidation are decreased by melatonin in diet-induced hypercholesterolemic rats. J Pineal Res 2000 28 : 150 155.
    • (2000) J Pineal Res , vol.28 , pp. 150-155
    • Hoyos, M.1    Guerrero, J.M.2    Perez-Cano, R.3
  • 73
    • 0030811912 scopus 로고    scopus 로고
    • Antioxidant role of melatonin in lipid peroxidation of human LDL
    • Abuja PM, Liebman P, Hayn M et al. Antioxidant role of melatonin in lipid peroxidation of human LDL. FEBS Lett 1997 413 : 289 293.
    • (1997) FEBS Lett , vol.413 , pp. 289-293
    • Abuja, P.M.1    Liebman, P.2    Hayn, M.3
  • 74
    • 0034813349 scopus 로고    scopus 로고
    • Melatonin protects against oxidized low-density lipoprotein-induced inhibition of nitric oxide production in human umbilical artery
    • Wakatsuki A, Okatani Y, Ikenoue N et al. Melatonin protects against oxidized low-density lipoprotein-induced inhibition of nitric oxide production in human umbilical artery. J Pineal Res 2001 31 : 281 288.
    • (2001) J Pineal Res , vol.31 , pp. 281-288
    • Wakatsuki, A.1    Okatani, Y.2    Ikenoue, N.3
  • 75
    • 17044423329 scopus 로고    scopus 로고
    • Elevated levels of oxidized low-density lipoprotein and impaired nocturnal synthesis of melatonin in patients with myocardial infarction
    • Dominguez-Rodriguez A, Abreu-Gonzalez P, Garcia-Gonzalez M et al. Elevated levels of oxidized low-density lipoprotein and impaired nocturnal synthesis of melatonin in patients with myocardial infarction. Atherosclerosis 2005 180 : 101 105.
    • (2005) Atherosclerosis , vol.180 , pp. 101-105
    • Dominguez-Rodriguez, A.1    Abreu-Gonzalez, P.2    Garcia-Gonzalez, M.3
  • 76
    • 47249124459 scopus 로고    scopus 로고
    • Melatonin treatment in peri- and postmenopausal women elevates serum high-density lipoprotein cholesterol levels without influencing total cholesterol levels
    • Tamura H, Nakamura Y, Narimatsu A et al. Melatonin treatment in peri- and postmenopausal women elevates serum high-density lipoprotein cholesterol levels without influencing total cholesterol levels. J Pineal Res 2008 45 : 101 105.
    • (2008) J Pineal Res , vol.45 , pp. 101-105
    • Tamura, H.1    Nakamura, Y.2    Narimatsu, A.3
  • 77
    • 0004608585 scopus 로고    scopus 로고
    • Melatonin: Lowering the high price of free radicals
    • Reiter RJ. Melatonin: lowering the high price of free radicals. News Physiol Sci 2000 15 : 246 250.
    • (2000) News Physiol Sci , vol.15 , pp. 246-250
    • Reiter, R.J.1
  • 78
    • 0027275716 scopus 로고
    • Melatonin decreases brain serotonin release, arterial pressure and heart rate in rats
    • Chuang JI, Chen SS, Lin MT. Melatonin decreases brain serotonin release, arterial pressure and heart rate in rats. Pharmacology 1993 47 : 91 97.
    • (1993) Pharmacology , vol.47 , pp. 91-97
    • Chuang, J.I.1    Chen, S.S.2    Lin, M.T.3
  • 79
    • 0017183792 scopus 로고
    • The effect of melatonin on pinealectomy-induced hypertension in the rat
    • Holmes SW, Sugden D. The effect of melatonin on pinealectomy-induced hypertension in the rat. Br J Pharmacol 1976 56 : 360 361.
    • (1976) Br J Pharmacol , vol.56 , pp. 360-361
    • Holmes, S.W.1    Sugden, D.2
  • 80
    • 0023071655 scopus 로고
    • Antihypertensive action of melatonin in the spontaneously hypertensive rat
    • Kawashima K, Miwa Y, Fujimoto K et al. Antihypertensive action of melatonin in the spontaneously hypertensive rat. Clin Exp Hypertens A 1987 9 : 1121 1131.
    • (1987) Clin Exp Hypertens A , vol.9 , pp. 1121-1131
    • Kawashima, K.1    Miwa, Y.2    Fujimoto, K.3
  • 81
    • 0015745789 scopus 로고
    • Effects in rats of pinealectomy and oxypertine on spontaneous locomotor activity and blood pressure during various light schedules
    • Karppanen H, Airaksinen MM, Sarkimaki I. Effects in rats of pinealectomy and oxypertine on spontaneous locomotor activity and blood pressure during various light schedules. Ann Med Exp Biol Fenn 1973 51 : 93 103.
    • (1973) Ann Med Exp Biol Fenn , vol.51 , pp. 93-103
    • Karppanen, H.1    Airaksinen, M.M.2    Sarkimaki, I.3
  • 82
    • 0031085015 scopus 로고    scopus 로고
    • Melatonin enhances cortisol levels in aged women: Reversible by estrogens
    • Cagnacci A, Sodani R, Yen SSC. Melatonin enhances cortisol levels in aged women: reversible by estrogens. J Pineal Res 1997 22 : 81 85.
    • (1997) J Pineal Res , vol.22 , pp. 81-85
    • Cagnacci, A.1    Sodani, R.2    Yen, S.S.C.3
  • 83
    • 0031992172 scopus 로고    scopus 로고
    • Influence of melatonin administration on the circulation of women
    • Cagnacci A, Arangino S, Angiolucci M et al. Influence of melatonin administration on the circulation of women. Am J Physiol 1998 274 : R335 R338.
    • (1998) Am J Physiol , vol.274
    • Cagnacci, A.1    Arangino, S.2    Angiolucci, M.3
  • 84
    • 0033135083 scopus 로고    scopus 로고
    • Effects of melatonin on vascular reactivity, catecholamine levels, and blood pressure in healthy men
    • Arangino S, Cagnacci A, Angiolucci M et al. Effects of melatonin on vascular reactivity, catecholamine levels, and blood pressure in healthy men. Am J Cardiol 1999 83 : 1417 1419.
    • (1999) Am J Cardiol , vol.83 , pp. 1417-1419
    • Arangino, S.1    Cagnacci, A.2    Angiolucci, M.3
  • 85
    • 0019417836 scopus 로고
    • Hypotensive effect of melatonin in essential hypertension
    • Birau N, Peterssen U, Meyer C, Gottschalk J. Hypotensive effect of melatonin in essential hypertension. IRCS Med Sci 1981 9 : 906 911.
    • (1981) IRCS Med Sci , vol.9 , pp. 906-911
    • Birau, N.1    Peterssen, U.2    Meyer, C.3    Gottschalk, J.4
  • 86
    • 68249122123 scopus 로고    scopus 로고
    • The circadian melatonin rhythm and its modulation: Possible impact on hypertension
    • Reiter RJ, Tan DX, Korkmaz A. The circadian melatonin rhythm and its modulation: possible impact on hypertension. J Hypertens 2009 6 : S17 S20.
    • (2009) J Hypertens , vol.6
    • Reiter, R.J.1    Tan, D.X.2    Korkmaz, A.3
  • 87
    • 72449198415 scopus 로고    scopus 로고
    • Melatonin and cardiac pathophysiology
    • Reiter RJ, Tan DX. Melatonin and cardiac pathophysiology. Heart Metab 2009 44 : 31 34.
    • (2009) Heart Metab , vol.44 , pp. 31-34
    • Reiter, R.J.1    Tan, D.X.2
  • 88
    • 33947280466 scopus 로고    scopus 로고
    • The effect of N-acetylcysteine and melatonin in adult spontaneously hypertensive rats with established hypertension
    • Pechanova O, Zicha J, Paulis L et al. The effect of N-acetylcysteine and melatonin in adult spontaneously hypertensive rats with established hypertension. Eur J Pharmacol 2007 561 : 129 136.
    • (2007) Eur J Pharmacol , vol.561 , pp. 129-136
    • Pechanova, O.1    Zicha, J.2    Paulis, L.3
  • 89
    • 67649957803 scopus 로고    scopus 로고
    • Melatonin improves cardiovascular function and ameliorates renal, cardiac and cerebral damage in rats with renovascular hypertension
    • Erşahin M, Sehirli O, Toklu HZ et al. Melatonin improves cardiovascular function and ameliorates renal, cardiac and cerebral damage in rats with renovascular hypertension. J Pineal Res 2009 47 : 97 106.
    • (2009) J Pineal Res , vol.47 , pp. 97-106
    • Erşahin, M.1    Sehirli, O.2    Toklu, H.Z.3
  • 90
    • 70450205127 scopus 로고    scopus 로고
    • Inflammatory systemic biomarkers in setting acute coronary syndromes- effects of the diurnal variation
    • Dominguez-Rodriguez A, Abreu-Gonzalez P, Kaski JC. Inflammatory systemic biomarkers in setting acute coronary syndromes- effects of the diurnal variation. Curr Drug Targets 2009 10 : 1001 1008.
    • (2009) Curr Drug Targets , vol.10 , pp. 1001-1008
    • Dominguez-Rodriguez, A.1    Abreu-Gonzalez, P.2    Kaski, J.C.3
  • 91
    • 27644466592 scopus 로고    scopus 로고
    • A review of the multiple actions of melatonin on the immune system
    • Carrillo-Vico A, Guerrero JM, Lardone PJ, Reiter RJ. A review of the multiple actions of melatonin on the immune system. Endocrine 2005 27 : 189 200.
    • (2005) Endocrine , vol.27 , pp. 189-200
    • Carrillo-Vico, A.1    Guerrero, J.M.2    Lardone, P.J.3    Reiter, R.J.4
  • 93
    • 1642619150 scopus 로고    scopus 로고
    • Light/dark patterns of interleukin-6 in relation to the pineal hormone melatonin in patients with acute myocardial infarction
    • Dominguez-Rodriguez A, Abreu-Gonzalez P, Garcia M et al. Light/dark patterns of interleukin-6 in relation to the pineal hormone melatonin in patients with acute myocardial infarction. Cytokine 2004 26 : 89 93.
    • (2004) Cytokine , vol.26 , pp. 89-93
    • Dominguez-Rodriguez, A.1    Abreu-Gonzalez, P.2    Garcia, M.3
  • 94
    • 29244465479 scopus 로고    scopus 로고
    • Relation of nocturnal melatonin levels to C-reactive protein concentration in patients with ST-segment elevation myocardial infarction
    • Dominguez-Rodriguez A, Garcia-Gonzalez M, Abreu-Gonzalez P et al. Relation of nocturnal melatonin levels to C-reactive protein concentration in patients with ST-segment elevation myocardial infarction. Am J Cardiol 2006 97 : 10 12.
    • (2006) Am J Cardiol , vol.97 , pp. 10-12
    • Dominguez-Rodriguez, A.1    Garcia-Gonzalez, M.2    Abreu-Gonzalez, P.3
  • 95
    • 34249947798 scopus 로고    scopus 로고
    • Relation of nocturnal melatonin levels to serum matrix metalloproteinase-9 concentrations in patients with myocardial infarction
    • Dominguez-Rodriguez A, Abreu-Gonzalez P, Garcia-Gonzalez MJ, Reiter RJ. Relation of nocturnal melatonin levels to serum matrix metalloproteinase-9 concentrations in patients with myocardial infarction. Thromb Res 2007 120 : 361 366.
    • (2007) Thromb Res , vol.120 , pp. 361-366
    • Dominguez-Rodriguez, A.1    Abreu-Gonzalez, P.2    Garcia-Gonzalez, M.J.3    Reiter, R.J.4
  • 96
    • 36849030791 scopus 로고    scopus 로고
    • Light/dark patterns of soluble vascular cell adhesion molecule-1 in relation to melatonin in patients with ST-segment elevation myocardial infarction
    • Dominguez-Rodriguez A, Abreu-Gonzalez P, Garcia-Gonzalez MJ et al. Light/dark patterns of soluble vascular cell adhesion molecule-1 in relation to melatonin in patients with ST-segment elevation myocardial infarction. J Pineal Res 2008 44 : 65 69.
    • (2008) J Pineal Res , vol.44 , pp. 65-69
    • Dominguez-Rodriguez, A.1    Abreu-Gonzalez, P.2    Garcia-Gonzalez, M.J.3
  • 97
    • 12744273107 scopus 로고    scopus 로고
    • When melatonin gets on your nerves: Its beneficial actions in experimental models of stroke
    • Reiter RJ, Tan DX, Leon J et al. When melatonin gets on your nerves: its beneficial actions in experimental models of stroke. Exp Biol Med 2005 230 : 104 117.
    • (2005) Exp Biol Med , vol.230 , pp. 104-117
    • Reiter, R.J.1    Tan, D.X.2    Leon, J.3
  • 99
    • 59149096686 scopus 로고    scopus 로고
    • Prevention of ischemia/reperfusion-induced cardiac apoptosis and injury by melatonin is independent of glutathione peroxidase 1
    • Chen Z, Chua CC, Gao J et al. Prevention of ischemia/reperfusion-induced cardiac apoptosis and injury by melatonin is independent of glutathione peroxidase 1. J Pineal Res 2009 46 : 235 241.
    • (2009) J Pineal Res , vol.46 , pp. 235-241
    • Chen, Z.1    Chua, C.C.2    Gao, J.3
  • 100
    • 0034971928 scopus 로고    scopus 로고
    • Melatonin protects against ischaemic-reperfusion myocardial damage
    • Salie R, Harper I, Cillie C et al. Melatonin protects against ischaemic-reperfusion myocardial damage. J Mol Cell Cardiol 2001 33 : 343 357.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 343-357
    • Salie, R.1    Harper, I.2    Cillie, C.3
  • 101
    • 0031709067 scopus 로고    scopus 로고
    • Ischemia/reperfusion-induced arrhythmias in the isolated rat heart: Prevention by melatonin
    • Tan DX, Manchester LC, Reiter RJ et al. Ischemia/reperfusion-induced arrhythmias in the isolated rat heart: prevention by melatonin. J Pineal Res 1998 25 : 184 191.
    • (1998) J Pineal Res , vol.25 , pp. 184-191
    • Tan, D.X.1    Manchester, L.C.2    Reiter, R.J.3
  • 102
    • 0034771505 scopus 로고    scopus 로고
    • Effects of melatonin on ischemia and reperfusion injury of the rat Herat
    • Szarszoi O, Asemu G, Vanecek J et al. Effects of melatonin on ischemia and reperfusion injury of the rat Herat. Cardiovasc Drugs Ther 2001 15 : 251 257.
    • (2001) Cardiovasc Drugs Ther , vol.15 , pp. 251-257
    • Szarszoi, O.1    Asemu, G.2    Vanecek, J.3
  • 103
    • 0036223583 scopus 로고    scopus 로고
    • Effects of physiological and pharmacological concentrations of melatonin on ischemia-reperfusion arrhythmias in rats: Can be the incidence of sudden cardiac death be reduced?
    • Sahna E, Olmez E, Acet A. Effects of physiological and pharmacological concentrations of melatonin on ischemia-reperfusion arrhythmias in rats: can be the incidence of sudden cardiac death be reduced? J Pineal Res 2002 32 : 194 198.
    • (2002) J Pineal Res , vol.32 , pp. 194-198
    • Sahna, E.1    Olmez, E.2    Acet, A.3
  • 104
    • 0036721033 scopus 로고    scopus 로고
    • Protective effects of melatonin on myocardial ischemia/reperfusion injury in vivo
    • Lee YM, Chen HR, Hsiao G et al. Protective effects of melatonin on myocardial ischemia/reperfusion injury in vivo. J Pineal Res 2002 33 : 72 80.
    • (2002) J Pineal Res , vol.33 , pp. 72-80
    • Lee, Y.M.1    Chen, H.R.2    Hsiao, G.3
  • 105
    • 1642562820 scopus 로고    scopus 로고
    • Regulation of antioxidant enzymes: A significant role for melatonin
    • Rodriguez C, Mayo JC, Sainz RM et al. Regulation of antioxidant enzymes: a significant role for melatonin. J Pineal Res 2004 36 : 1 9.
    • (2004) J Pineal Res , vol.36 , pp. 1-9
    • Rodriguez, C.1    Mayo, J.C.2    Sainz, R.M.3
  • 106
    • 27644598160 scopus 로고    scopus 로고
    • Protective effects of melatonin on myocardial ischemia/reperfusion induced infarct size and oxidative damage
    • Sahna E, Parlakpinar H, Turkoz Y, Acet A. Protective effects of melatonin on myocardial ischemia/reperfusion induced infarct size and oxidative damage. Physiol Res 2005 54 : 491 495.
    • (2005) Physiol Res , vol.54 , pp. 491-495
    • Sahna, E.1    Parlakpinar, H.2    Turkoz, Y.3    Acet, A.4
  • 107
    • 0037405817 scopus 로고    scopus 로고
    • Protective effect of melatonin on myocardial infarction
    • Chen Z, Chua CC, Gao J et al. Protective effect of melatonin on myocardial infarction. Am J Physiol 2003 284 : H1618 H1624.
    • (2003) Am J Physiol , vol.284
    • Chen, Z.1    Chua, C.C.2    Gao, J.3
  • 108
    • 45249103302 scopus 로고    scopus 로고
    • Association of ischemia-modified albumin and melatonin in patients with ST-elevation myocardial infarction
    • Dominguez-Rodriguez A, Abreu-Gonzalez P, Garcia-Gonzalez MJ et al. Association of ischemia-modified albumin and melatonin in patients with ST-elevation myocardial infarction. Atherosclerosis 2007 199 : 73 78.
    • (2007) Atherosclerosis , vol.199 , pp. 73-78
    • Dominguez-Rodriguez, A.1    Abreu-Gonzalez, P.2    Garcia-Gonzalez, M.J.3
  • 109
    • 73349096315 scopus 로고    scopus 로고
    • Molecular time: An often overlooked dimension to cardiovascular disease
    • Martino TA, Sole MJ. Molecular time: an often overlooked dimension to cardiovascular disease. Circ Res 2009 105 : 1047 1061.
    • (2009) Circ Res , vol.105 , pp. 1047-1061
    • Martino, T.A.1    Sole, M.J.2
  • 110
    • 77949269038 scopus 로고    scopus 로고
    • Effects of circadian disruption on the cardiometabolic system
    • Rüger M, Scheer FA. Effects of circadian disruption on the cardiometabolic system. Rev Endocr Metab Disord 2009, doi:.
    • (2009) Rev Endocr Metab Disord
    • Rüger, M.1    Scheer, F.A.2
  • 111
    • 18444414586 scopus 로고    scopus 로고
    • Coordinated transcription of key pathways in the mouse by the circadian clock
    • Panda S, Antoch MP, Miller BH et al. Coordinated transcription of key pathways in the mouse by the circadian clock. Cell 2002 109 : 307 320.
    • (2002) Cell , vol.109 , pp. 307-320
    • Panda, S.1    Antoch, M.P.2    Miller, B.H.3
  • 112
    • 68249092574 scopus 로고    scopus 로고
    • Massively parallel sequencing: The next big thing in genetic medicine
    • Tucker T, Marra M, Friedman JM. Massively parallel sequencing: the next big thing in genetic medicine. Am J Hum Genet 2009 85 : 142 154.
    • (2009) Am J Hum Genet , vol.85 , pp. 142-154
    • Tucker, T.1    Marra, M.2    Friedman, J.M.3
  • 113
    • 70350220595 scopus 로고    scopus 로고
    • Genotyping technologies for genetic research
    • Ragoussis J. Genotyping technologies for genetic research. Annu Rev Genomics Hum Genet 2009 10 : 117 133.
    • (2009) Annu Rev Genomics Hum Genet , vol.10 , pp. 117-133
    • Ragoussis, J.1
  • 114
    • 47349112671 scopus 로고    scopus 로고
    • Arylalkylamine-N-acetyltransferase (AANAT) genotype as a personal trait in melatonin synthesis
    • Blomeke B, Golka K, Griefahn B, Roemer HC. Arylalkylamine-N- acetyltransferase (AANAT) genotype as a personal trait in melatonin synthesis. J Toxicol Environ Health 2008 71 : 874 876.
    • (2008) J Toxicol Environ Health , vol.71 , pp. 874-876
    • Blomeke, B.1    Golka, K.2    Griefahn, B.3    Roemer, H.C.4
  • 115
    • 0037611063 scopus 로고    scopus 로고
    • Significant association of the arylalkylamine N-acetyltransferase (AA-NAT) gene with delayed sleep phase syndrome
    • Hohjoh H, Takasu M, Shishikura K et al. Significant association of the arylalkylamine N-acetyltransferase (AA-NAT) gene with delayed sleep phase syndrome. Neurogenetics 2003 4 : 151 153.
    • (2003) Neurogenetics , vol.4 , pp. 151-153
    • Hohjoh, H.1    Takasu, M.2    Shishikura, K.3
  • 116
    • 55449106418 scopus 로고    scopus 로고
    • Association study of tryptophan hydroxylase 1 and arylalkylamine N-acetyltransferase polymorphisms with adolescent idiopathic scoliosis in Han Chinese
    • Wang H, Wu Z, Zhuang Q et al. Association study of tryptophan hydroxylase 1 and arylalkylamine N-acetyltransferase polymorphisms with adolescent idiopathic scoliosis in Han Chinese. Spine 2008 33 : 2199 2203.
    • (2008) Spine , vol.33 , pp. 2199-2203
    • Wang, H.1    Wu, Z.2    Zhuang, Q.3
  • 117
    • 77954338806 scopus 로고    scopus 로고
    • Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6
    • Doi M, Takahashi Y, Komatsu R et al. Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6. Nat Med 2009, doi:.
    • (2009) Nat Med
    • Doi, M.1    Takahashi, Y.2    Komatsu, R.3
  • 118
    • 0025246660 scopus 로고
    • Melatonin concentrations in the sudden infant death syndrome
    • Sturner WQ, Lynch HJ, Deng MH et al. Melatonin concentrations in the sudden infant death syndrome. Forensic Sci Int 1990 45 : 171 180.
    • (1990) Forensic Sci Int , vol.45 , pp. 171-180
    • Sturner, W.Q.1    Lynch, H.J.2    Deng, M.H.3
  • 119
    • 0028287625 scopus 로고
    • Sudden infant death syndrome: A genetically determined impaired maturation of the photoneuroendocrine system. A unifying hypothesis
    • Weissbluth L, Weissbluth M. Sudden infant death syndrome: a genetically determined impaired maturation of the photoneuroendocrine system. A unifying hypothesis. J Theor Biol 1994 167 : 13 25.
    • (1994) J Theor Biol , vol.167 , pp. 13-25
    • Weissbluth, L.1    Weissbluth, M.2
  • 120
    • 27644449587 scopus 로고    scopus 로고
    • Functional MT1 and MT2 melatonin receptors in mammals
    • Dubocovich ML, Markowska M. Functional MT1 and MT2 melatonin receptors in mammals. Endocrine 2005 27 : 101 110.
    • (2005) Endocrine , vol.27 , pp. 101-110
    • Dubocovich, M.L.1    Markowska, M.2
  • 121
    • 0035669124 scopus 로고    scopus 로고
    • 24h variation in the expression of the mt1 melatonin receptor subtype in coronary arteries derived from patients with coronary heart disease
    • Ekmekcioglu C, Haslmayer P, Philipp C et al. 24h variation in the expression of the mt1 melatonin receptor subtype in coronary arteries derived from patients with coronary heart disease. Chronobiol Int 2001 18 : 973 985.
    • (2001) Chronobiol Int , vol.18 , pp. 973-985
    • Ekmekcioglu, C.1    Haslmayer, P.2    Philipp, C.3
  • 122
    • 10744232166 scopus 로고    scopus 로고
    • The melatonin receptor subtype MT2 is present in the human cardiovascular system
    • Ekmekcioglu C, Thalhammer T, Humpeler S et al. The melatonin receptor subtype MT2 is present in the human cardiovascular system. J Pineal Res 2003 35 : 40 44.
    • (2003) J Pineal Res , vol.35 , pp. 40-44
    • Ekmekcioglu, C.1    Thalhammer, T.2    Humpeler, S.3
  • 123
    • 47249088189 scopus 로고    scopus 로고
    • Melatonin receptors, heterodimerization, signal transduction and binding sites: What's new?
    • Jockers R, Maurice P, Boutin JA et al. Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new?. Br J Pharmacol 2008 154 : 1182 1195.
    • (2008) Br J Pharmacol , vol.154 , pp. 1182-1195
    • Jockers, R.1    Maurice, P.2    Boutin, J.A.3
  • 124
    • 58049198441 scopus 로고    scopus 로고
    • Polymorphisms within the novel type 2 diabetes risk locus MTNR1B determine beta-cell function
    • Staiger H, Machicao F, Schäfer SA et al. Polymorphisms within the novel type 2 diabetes risk locus MTNR1B determine beta-cell function. PLoS ONE 2008 3 : e3962.
    • (2008) PLoS ONE , vol.3 , pp. 3962
    • Staiger, H.1    MacHicao, F.2    Schäfer, S.A.3
  • 125
    • 67650694101 scopus 로고    scopus 로고
    • Common genetic variation in the melatonin receptor 1B gene (MTNR1B) is associated with decreased early-phase insulin response
    • Langenberg C, Pascoe L, Mari A et al. Common genetic variation in the melatonin receptor 1B gene (MTNR1B) is associated with decreased early-phase insulin response. Diabetologia 2009 52 : 1537 1542.
    • (2009) Diabetologia , vol.52 , pp. 1537-1542
    • Langenberg, C.1    Pascoe, L.2    Mari, A.3
  • 126
    • 58149156287 scopus 로고    scopus 로고
    • Variants in MTNR1B influence casting glucose levels
    • Prokopenko Y, Langenberg C, Florez JC et al. Variants in MTNR1B influence casting glucose levels. Nat Genet 2009 41 : 77 81.
    • (2009) Nat Genet , vol.41 , pp. 77-81
    • Prokopenko, Y.1    Langenberg, C.2    Florez, J.C.3
  • 127
    • 58149175669 scopus 로고    scopus 로고
    • Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion
    • Lyssenko V, Nagorny CL, Erdos MR et al. Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion. Nat Genet 2009 41 : 82 88.
    • (2009) Nat Genet , vol.41 , pp. 82-88
    • Lyssenko, V.1    Nagorny, C.L.2    Erdos, M.R.3
  • 128
    • 23744495865 scopus 로고    scopus 로고
    • Positive relationship between melatonin receptor type 1B polymorphism and rheumatoid factor in rheumatoid arthritis patients in the Korean population
    • Ha E, Choe BK, Jung KH et al. Positive relationship between melatonin receptor type 1B polymorphism and rheumatoid factor in rheumatoid arthritis patients in the Korean population. J Pineal Res 2005 39 : 201 205.
    • (2005) J Pineal Res , vol.39 , pp. 201-205
    • Ha, E.1    Choe, B.K.2    Jung, K.H.3
  • 129
    • 84925562723 scopus 로고    scopus 로고
    • Melatonin receptor 1B (MTNR1B); SNP rs1387153; SNP rs10830963
    • Melatonin receptor 1B (MTNR1B); SNP rs1387153; SNP rs10830963. SciBX 2009, doi:.
    • (2009) SciBX
  • 130
    • 1842844418 scopus 로고    scopus 로고
    • The EGIR-RISC STUDY (The European group for the study of insulin resistance: Relationship between insulin sensitivity and cardiovascular disease risk): I. Methodology and objectives
    • Hills SA, Balkau B, Coppack SW et al. The EGIR-RISC STUDY (The European group for the study of insulin resistance: relationship between insulin sensitivity and cardiovascular disease risk): I. Methodology and objectives. Diabetologia 2004 47 : 566 570.
    • (2004) Diabetologia , vol.47 , pp. 566-570
    • Hills, S.A.1    Balkau, B.2    Coppack, S.W.3
  • 131
    • 0034987699 scopus 로고    scopus 로고
    • Identification of single-nucleotide polymorphisms (SNPs) of human N-acetyltransferase genes NAT1, NAT2, AANAT, ARD1 and L1CAM in the Japanese population
    • Sekine A, Saito S, Iida A et al. Identification of single-nucleotide polymorphisms (SNPs) of human N-acetyltransferase genes NAT1, NAT2, AANAT, ARD1 and L1CAM in the Japanese population. J Hum Genet 2001 46 : 314 319.
    • (2001) J Hum Genet , vol.46 , pp. 314-319
    • Sekine, A.1    Saito, S.2    Iida, A.3
  • 132
    • 73549097512 scopus 로고    scopus 로고
    • Genetic variants associated with Lp(a) lipoprotein level and coronary disease
    • Clarke R, Peden JF, Hopewell JC et al. Genetic variants associated with Lp(a) lipoprotein level and coronary disease. N Engl J Med 2009 361 : 2518 2528.
    • (2009) N Engl J Med , vol.361 , pp. 2518-2528
    • Clarke, R.1    Peden, J.F.2    Hopewell, J.C.3
  • 133
    • 33645516778 scopus 로고    scopus 로고
    • Sequence variants in the melatonin-related receptor gene (GPR50) associate with circulating triglyceride and HDL levels
    • Bhattacharyya S, Luan J, Challis B et al. Sequence variants in the melatonin-related receptor gene (GPR50) associate with circulating triglyceride and HDL levels. J Lipid Res 2006 47 : 761 766.
    • (2006) J Lipid Res , vol.47 , pp. 761-766
    • Bhattacharyya, S.1    Luan, J.2    Challis, B.3
  • 134
    • 0035917910 scopus 로고    scopus 로고
    • Effects of short-term melatonin administration on lipoprotein metabolism in normolipidemic postmenopausal women
    • Wakatsuki A, Okatani Y, Ikenoue N et al. Effects of short-term melatonin administration on lipoprotein metabolism in normolipidemic postmenopausal women. Maturitas 2001 38 : 171 177.
    • (2001) Maturitas , vol.38 , pp. 171-177
    • Wakatsuki, A.1    Okatani, Y.2    Ikenoue, N.3
  • 135
    • 0036275086 scopus 로고    scopus 로고
    • Melatonin protects the heart against both ischemia/reperfusion injury and chemotherapeutic drugs
    • Reiter RJ, Tan DX, Sainz RN, Mayo JC. Melatonin protects the heart against both ischemia/reperfusion injury and chemotherapeutic drugs. Cardiovasc Drugs Ther 2002 16 : 5 6.
    • (2002) Cardiovasc Drugs Ther , vol.16 , pp. 5-6
    • Reiter, R.J.1    Tan, D.X.2    Sainz, R.N.3    Mayo, J.C.4
  • 136
    • 36849090114 scopus 로고    scopus 로고
    • Epigenetic regulation: A new research area for melatonin?
    • Korkmaz A, Reiter RJ. Epigenetic regulation: a new research area for melatonin? J Pineal Res 2008 44 : 41 44.
    • (2008) J Pineal Res , vol.44 , pp. 41-44
    • Korkmaz, A.1    Reiter, R.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.