The future: Genes, physical activity and health

Acta Physiologica

Volumn 199, Issue 4, 2010, Pages 549-556

  Booth, F W ^a,b   Laye, M J ^a,b,c  

^a UNIVERSITY OF MISSOURI   (United States)

^b University of Missouri   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

control group; exercise; individualized medicine; non responders; preventive medicine

Indexed keywords

ADAPTATION; CHRONIC DISEASE; ENVIRONMENTAL FACTOR; EXERCISE; GENETIC VARIABILITY; GENETICS; GENOME; HEALTH STATUS; HUMAN; PHENOTYPE; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RESEARCH; REVIEW; TECHNOLOGY; ANIMAL; FORECASTING; GENE; HEALTH; PERSONALIZED MEDICINE; TRENDS;

ANIMALS; CHRONIC DISEASE; EXERCISE; FORECASTING; GENES; HEALTH; HUMANS; INDIVIDUALIZED MEDICINE; PHARMACEUTICAL PREPARATIONS;

DRUG;

EID: 77954329816     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2010.02117.x     Document Type: Review

References (32)

1. Anonymous. 2005. The American Heritage Science Dictionary. Houghton Mifflin
2. Anonymous. 2007. Merriam-Webster's Medical Dictionary. Merriam-Webster
3. Anonymous. 2008. Encyclopedia Britannica. Encyclopedia Britannica
4. Bjornholt, J.V., Erikssen, G., Liestol, K., Jervell, J., Erikssen, J. Thaulow, E. 2001. Prediction of Type 2 diabetes in healthy middle-aged men with special emphasis on glucose homeostasis. Results from 22.5 years' follow-up. Diabet Med 18, 261 267.
5. Booth, F.W. Lees, S.J. 2006. Physically active subjects should be the control group. Med Sci Sports Exerc 38, 405 406.
6. Bouchard, C. Rankinen, T. 2001. Individual differences in response to regular physical activity. Med Sci Sports Exerc 33, S446 S451 discussion S452-S453.
7. Bouchard, C., An, P., Rice, T., Skinner, J.S., Wilmore, J.H., Gagnon, J., Perusse, L., Leon, A.S. Rao, D.C. 1999. Familial aggregation of VO(2max) response to exercise training: results from the HERITAGE Family Study. J Appl Physiol 87, 1003 1008.
8. Bramble, D.M. Lieberman, D.E. 2004. Endurance running and the evolution of Homo. Nature 432, 345 352.
9. Carnethon, M.R., Gidding, S.S., Nehgme, R., Sidney, S., Jacobs, D.R., Jr. Liu, K. 2003. Cardiorespiratory fitness in young adulthood and the development of cardiovascular disease risk factors. JAMA 290, 3092 3100. (Pubitemid 37548115)
10. Cordain, L., Gotshall, R.W., Eaton, S.B. Eaton, S.B., 3rd. 1998. Physical activity, energy expenditure and fitness: an evolutionary perspective. Int J Sports Med 19, 328 335.
11. DECODE Study Group. 2003. Age- and sex-specific prevalences of diabetes and impaired glucose regulation in 13 European cohorts. Diabetes Care 26, 61 69.
12. Eriksson, K.F. Lindgarde, F. 1996. Poor physical fitness, and impaired early insulin response but late hyperinsulinaemia, as predictors of NIDDM in middle-aged Swedish men. Diabetologia 39, 573 579.
13. Fritz, T., Kramer, D.K., Karlsson, H.K., Galuska, D., Engfeldt, P., Zierath, J.R. Krook, A. 2006. Low-intensity exercise increases skeletal muscle protein expression of PPARdelta and UCP3 in type 2 diabetic patients. Diabetes Metab Res Rev 22, 492 498.
14. Hayes, M., Chustek, M., Heshka, S., Wang, Z., Pietrobelli, A. Heymsfield, S.B. 2005. Low physical activity levels of modern Homo sapiens among free-ranging mammals. Int J Obes (Lond) 29, 151 156.
15. Hu, G., Lakka, T.A., Kilpelainen, T.O. Tuomilehto, J. 2007. Epidemiological studies of exercise in diabetes prevention. Appl Physiol Nutr Metab 32, 583 595.
16. Kahn, A. Fraga, M.F. 2009. Epigenetics and aging: status, challenges, and needs for the future. J Gerontol A Biol Sci Med Sci 64, 195 198.
17. Katzmarzyk, P.T. Janssen, I. 2004. The economic costs associated with physical inactivity and obesity in Canada: an update. Can J Appl Physiol 29, 90 115.
18. Kogure, A., Yoshida, T., Sakane, N., Umekawa, T., Takakura, Y. Kondo, M. 1998. Synergic effect of polymorphisms in uncoupling protein 1 and beta3-adrenergic receptor genes on weight loss in obese Japanese. Diabetologia 41, 1399.
19. 2max to training in 60-71 yr olds. J Appl Physiol 71, 2004 2011.
20. Laye, M.J., Rector, R.S., Borengasser, S.J., Naples, S.P., Uptergrove, G.M., Ibdah, J.A., Booth, F.W. Thyfault, J.P. 2009. Cessation of daily wheel running differentially alters fat oxidation capacity in liver, muscle, and adipose tissue. J Appl Physiol 106, 161 168.
21. Lynch, J., Helmrich, S.P., Lakka, T.A., Kaplan, G.A., Cohen, R.D., Salonen, R. Salonen, J.T. 1996. Moderately intense physical activities and high levels of cardiorespiratory fitness reduce the risk of non-insulin-dependent diabetes mellitus in middle-aged men. Arch Intern Med 156, 1307 1314.
22. Narayan, K.M., Boyle, J.P., Thompson, T.J., Sorensen, S.W. Williamson, D.F. 2003. Lifetime risk for diabetes mellitus in the United States. JAMA 290, 1884 1890.
23. Narayan, K.M., Boyle, J.P., Geiss, L.S., Saaddine, J.B. Thompson, T.J. 2006. Impact of recent increase in incidence on future diabetes burden: U.S., 2005-2050. Diabetes Care 29, 2114 2116.
24. Narkar, V.A., Downes, M., Yu, R.T., Embler, E., Wang, Y.X., Banayo, E., Mihaylova, M.M., Nelson, M.C., Zou, Y., Juguilon, H., Kang, H., Shaw, R.J. Evans, R.M. 2008. AMPK and PPARdelta agonists are exercise mimetics. Cell 134, 405 415.
25. Sakane, N., Yoshida, T., Umekawa, T., Kogure, A., Takakura, Y. Kondo, M. 1997. Effects of Trp64Arg mutation in the beta 3-adrenergic receptor gene on weight loss, body fat distribution, glycemic control, and insulin resistance in obese type 2 diabetic patients. Diabetes Care 20, 1887 1890.
26. Sawada, S.S., Lee, I.M., Muto, T., Matuszaki, K. Blair, S.N. 2003. Cardiorespiratory fitness and the incidence of type 2 diabetes: prospective study of Japanese men. Diabetes Care 26, 2918 2922. (Pubitemid 37205569)
27. Schwartz, D. Collins, F. 2007. Medicine. Environmental biology and human disease. Science 316, 695 696.
28. Sisson, S.B., Katzmarzyk, P.T., Earnest, C.P., Bouchard, C., Blair, S.N. Church, T.S. 2009. Volume of exercise and fitness nonresponse in sedentary, postmenopausal women. Med Sci Sports Exerc 41, 539 545.
29. Vollaard, N.B., Constantin-Teodosiu, D., Fredriksson, K., Rooyackers, O., Jansson, E., Greenhaff, P.L., Timmons, J.A. Sundberg, C.J. 2009. Systematic analysis of adaptations in aerobic capacity and submaximal energy metabolism provides a unique insight into determinants of human aerobic performance. J Appl Physiol 106, 1479 1486.
30. Wei, M., Gibbons, L.W., Kampert, J.B., Nichaman, M.Z. Blair, S.N. 2000. Low cardiorespiratory fitness and physical inactivity as predictors of mortality in men with type 2 diabetes. Ann Intern Med 132, 605 611.
31. Wild, S., Roglic, G., Green, A., Sicree, R. King, H. 2004. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 27, 1047 1053.
32. Yoshida, T., Sakane, N., Umekawa, T., Sakai, M., Takahashi, T. Kondo, M. 1995. Mutation of beta 3-adrenergic-receptor gene and response to treatment of obesity. Lancet 346, 1433 1434.