The role of postmortem cardiac markers in the diagnosis of acute myocardial infarction

Journal of Forensic Sciences

Volumn 55, Issue 4, 2010, Pages 1088-1091

  Batalis, Nick I ^a   Marcus, Bradley J ^b   Papadea, Christine N ^a   Collins, Kim A ^c  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b Professional Pathology Services   (United States)

^c Fulton County Medical Examiner's Office   (United States)

Author keywords

autopsy; cardiac markers; death; forensic pathology; forensic sciences; heart; myocardial infarction

Indexed keywords

BIOLOGICAL MARKER; CREATINE KINASE MB; TROPONIN I;

ADULT; ARTICLE; BLOOD; CASE CONTROL STUDY; CORONARY ARTERY THROMBOSIS; FEMALE; FORENSIC PATHOLOGY; HEART INFARCTION; HUMAN; MALE; MIDDLE AGED; PATHOLOGY;

ADULT; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CORONARY THROMBOSIS; CREATINE KINASE, MB FORM; FEMALE; FORENSIC PATHOLOGY; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; TROPONIN I;

EID: 77954321338     PISSN: 00221198     EISSN: 15564029     Source Type: Journal    
DOI: 10.1111/j.1556-4029.2010.01368.x     Document Type: Article

References (20)

1. Jaffe AS, Babuin L, Apple FS. Biomarkers in acute cardiac disease: the present and the future. J Am Coll Cardiol 2006 48 (1 1 11.
2. Kavsak PA, MacRae AR, Lustig V, Bhargava R, Vandersluis R, Palomaki GE, et al. The impact of the ESC/ACC redefinition of myocardial infarction and new sensitive troponin assays on the frequency of acute myocardial infarction. Am Heart J 2006 152 (1 118 125.
3. Davies SJ, Gaze DC, Collinson PO. Investigation of cardiac troponins in postmortem subjects: comparing antemortem and postmortem levels. Am J Forensic Med Pathol 2005 26 (3 213 215.
4. Cina SJ, Thompson WC, Fischer JR Jr., Brown DK, Titus JM, Smialek JE. A study of various morphologic variables and troponin I in pericardial fluid as possible discriminators of sudden cardiac death. Am J Forensic Med Pathol 1999 20 (4 333 337.
5. Zhu BL, Ishikawa T, Michiue T, Li DR, Zhao D, Oritani S, et al. Postmortem cardiac troponin T levels in the blood and pericardial fluid. Part 1. Analysis with special regard to traumatic causes of death. Leg Med (Tokyo) 2006 8 (2 86 93. (Pubitemid 43243308)
6. Zhu BL, Ishikawa T, Michiue T, Li DR, Zhao D, Kamikodai Y, et al. Postmortem cardiac troponin T levels in the blood and pericardial fluid. Part 2: analysis for application in the diagnosis of sudden cardiac death with regard to pathology. Leg Med (Tokyo) 2006 8 (2 94 101. (Pubitemid 43243309)
7. Ooi DS, Isotalo PA, Veinot JP. Correlation of antemortem serum creatine kinase, creatine kinase-MB, troponin I, and troponin T with cardiac pathology. Clin Chem 2000 46 (3 338 344.
8. Perez-Carceles MD, Noguera J, Jimenez JL, Martinez P, Luna A, Osuna E. Diagnostic efficacy of biochemical markers in diagnosis post-mortem of ischaemic heart disease. Forensic Sci Int 2004 142 (1 1 7.
9. Osuna E, Perez-Carceles MD, Alvarez MV, Noguera J, Luna A. Cardiac troponin I (cTn I) and the postmortem diagnosis of myocardial infarction. Int J Legal Med 1998 111 (4 173 176.
10. Osuna E, Perez-Carceles MD, Vieira DN, Luna A. Distribution of biochemical markers in biologic fluids: application to the postmortem diagnosis of myocardial infarction. Am J Forensic Med Pathol 1998 19 (2 123 128.
11. Khalifa AB, Najjar M, Addad F, Turki E, Mghirbi T. Cardiac troponin T (cTn T) and the postmortem diagnosis of sudden death. Am J Forensic Med Pathol 2006 27 (2 175 177.
12. Cina SJ, Brown DK, Smialek JE, Collins KA. A rapid postmortem cardiac troponin T assay: laboratory evidence of sudden cardiac death. Am J Forensic Med Pathol 2001 22 (2 173 176.
13. Ellingsen CL, Hetland O. Serum concentrations of cardiac troponin T in sudden death. Am J Forensic Med Pathol 2004 25 (3 213 215.
14. Adegboyega PA, Adesokan A, Haque AK, Boor PJ. Sensitivity and specificity of triphenyl tetrazolium chloride in the gross diagnosis of acute myocardial infarcts. Arch Pathol Lab Med 1997 121 (10 1063 1068.
15. Agdal N, Andersen MT. The value of succinate dehydrogenase stain in the post-mortem diagnosis of early acute myocardial infarction. A forensic study. Forensic Sci 1978 11 (3 223 230.
16. Edston E, Grontoft L, Johnsson J. TUNEL: a useful screening method in sudden cardiac death. Int J Legal Med 2002 116 (1 22 6.
17. Blanco Pampin J, Garcia Rivero SA, Otero Cepeda XL, Vazquez Boquete A, Forteza Vila J, Hinojal Fonseca R. Immunohistochemical expression of HIF-1alpha in response to early myocardial ischemia. J Forensic Sci 2006 51 (1 120 124.
18. Fishbein MC, Wang T, Matijasevic M, Hong L, Apple FS. Myocardial tissue troponins T and I. An immunohistochemical study in experimental models of myocardial ischemia. Cardiovasc Pathol 2003 12 (2 65 71.
19. Campobasso CP, Dell'Erba AS, Addante A, Zotti F, Marzullo A, Colonna MF. Sudden cardiac death and myocardial ischemia indicators: a comparative study of four immunohistochemical markers. Am J Forensic Med Pathol 2008 29 (2 154 161.
20. Zhu BL, Ishikawa T, Michiue T, Li DR, Zhao D, Tanaka S, et al. Postmortem pericardial natriuretic peptides as markers of cardiac function in medico-legal autopsies. Int J Legal Med 2007 121 (1 28 35.