Hepatocellular carcinoma in patients with thalassaemia syndromes: Clinical characteristics and outcome in a long term single centre experience

British Journal of Haematology

Volumn 150, Issue 2, 2010, Pages 245-247

  Restivo Pantalone, Gaetano ^a   Renda, Disma ^a   Valenza, Franco ^a   D'Amato, Fabio ^a   Vitrano, Angela ^a   Cassarà, Filippo ^a   Rigano, Paolo ^a   Salvo, Veronica Di ^a   Giangreco, Antonino ^a   Bevacqua, Elvira ^a   Maggio, Aurelio ^a  

^a Ospedali Riuniti Villa Sofia Cervello   (Italy)

Author keywords

cirrhosis; hepatitis C; hepatocellular carcinoma; iron overload; thalassaemia

Indexed keywords

ALCOHOL; ALPHA FETOPROTEIN; CONTRAST MEDIUM; DEFERIPRONE; DEFEROXAMINE; FERRITIN; HEPATITIS B SURFACE ANTIGEN; IRON; SORAFENIB; VIRUS RNA;

ADULT; CANCER RISK; CANCER SURVIVAL; CHEMOEMBOLIZATION; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; ECHOGRAPHY; FEMALE; FERRITIN BLOOD LEVEL; HEPATITIS C VIRUS; HUMAN; HUMAN TISSUE; IRON CHELATION; LETTER; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER LEVEL; LIVER RESECTION; LIVER TRANSPLANTATION; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RADIOFREQUENCY ABLATION; THALASSEMIA; THALASSEMIA INTERMEDIA; THALASSEMIA MAJOR;

ADULT; AGED; BLOOD TRANSFUSION; CARCINOMA, HEPATOCELLULAR; FEMALE; HEPATITIS C, CHRONIC; HUMANS; IRON OVERLOAD; LIVER NEOPLASMS; MALE; MIDDLE AGED; PROGNOSIS; THALASSEMIA;

EID: 77954319602     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2010.08180.x     Document Type: Letter

References (10)

1. Borgna-Pignatti, C., Vergine, G., Lombardo, T., Cappellini, M., Cianciulli, P., Maggio, A., Renda, D., Lai, M., Mandas, A., Forni, G., Piga, A. Bisconte, M. (2004) Hepatocellular carcinoma in the thalassaemia syndrome. British Journal of Haematology, 124, 114 117.
2. Borgna-Pignatti, C., Cappellini, M., De Stefano, P., Del Vecchio, G., Forni, G., Gamberini, M., Ghilardi, R., Origa, R., Piga, A., Romeo, M., Zhao, H. Cnaan, A. (2005) Survival and complications in Thalassemia. Annals of the New York Academy of Sciences, 1054, 40 47.
3. Bruix, J., Sherman, M., Llovet, J.M., Beaugrand, M., Lencioni, R., Burroughs, A.K., Christensen, E., Pagliaro, L., Colombo, M. Rodés, J. EASL Panel of Experts on HCC (2001) Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver. Journal of Hepatology, 35, 421 430.
4. Cohen, A., Galanello, R., Pennel, D., Cunningham, M. Vichinsky, E. (2004) Thalassemia. Hematology American Society of Hematology Education Program, 14 34.
5. Kowdley, K. (2004) Iron, hemochromatosis, and hepatocellular carcinoma. Gastroenterology, 127, S79 S86.
6. Maggio, A. (2007) Light and shadows in the iron chelation treatment of haematological diseases. British Journal of Haematology, 138, 407 421.
7. Maggio, A., Vitrano, A., Capra, M., Cuccia, L., Gagliardotto, F., Filosa, A., Romeo, M.A., Magnano, C., Caruso, V., Argento, C., Gerardi, C., Campisi, S., Violi, P., Malizia, R., Cianciulli, P., Rizzo, M., D'Ascola, D.G., Quota, A., Prossomariti, L., Fidone, C., Rigano, P., Pepe, A., D'Amico, G., Morabito, A. Gluud, C. (2009) Long-term sequential deferiprone-deferoxamine versus deferiprone alone for thalassaemia major patients: a randomized clinical trial. British Journal of Haematology, 145, 245 254.
8. Mancuso, A., Sciarrino, E., Renda, M.C. Maggio, A. (2006) A prospective study of hepatocellular carcinoma incidence in thalassemia. Hemoglobin, 30, 119 124.
9. Parkin, D.M. (2001) Global cancer statistics in the year 2000. Lancet Oncology, 2, 533 543.
10. Vento, S., Cainelli, F. Cesario, F. (2006) Infections and thalassaemia. Lancet Infectious Diseases, 6, 226 233.