Unexpected enhancement in biological activity of a GPCR ligand induced by an oligoethylene glycol substituent

Journal of the American Chemical Society

Volumn 132, Issue 26, 2010, Pages 8844-8845

  Jiarpinitnun, Chutima ^a,b   Kiessling, Laura L ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Departments of Biochemistry University of Wisconsin Madison ^*  (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; PEPTIDES; POLYETHYLENE OXIDES; SIGNAL TRANSDUCTION;

BIOLOGICAL ACTIVITIES; BIOLOGICALLY ACTIVE MOLECULES; CHEMOATTRACTANTS; FORMYL PEPTIDE RECEPTOR; G PROTEIN COUPLED RECEPTORS; HALF LIVES; N-FORMYL-METHIONINE-LEUCINE-PHENYLALANINE; OLIGOETHYLENE GLYCOLS; TRANSMEMBRANES;

POLYETHYLENE GLYCOLS;

ETHYLENE GLYCOL DERIVATIVE; FORMYLPEPTIDE RECEPTOR; G PROTEIN COUPLED RECEPTOR; LIGAND; MACROGOL DERIVATIVE; PEPTIDE;

ARTICLE; BIOLOGICAL ACTIVITY; CELL MIGRATION; CHEMOTAXIS; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; STRUCTURE ACTIVITY RELATION; CELL MEMBRANE; CHEMISTRY; DRUG EFFECTS; METABOLISM; U937 CELL LINE;

CELL MEMBRANE; CHEMOTAXIS; HUMANS; LIGANDS; PEPTIDES; POLYETHYLENE GLYCOLS; RECEPTORS, FORMYL PEPTIDE; STRUCTURE-ACTIVITY RELATIONSHIP; U937 CELLS;

EID: 77954301795     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja102640c     Document Type: Article

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