Synthesis and application of [1,2,5]triazepane and [1,2,5]oxadiazepane as versatile structural units for drug discovery

Chemical and Pharmaceutical Bulletin

Volumn 58, Issue 7, 2010, Pages 1001-1002

  Suzuki, Hideyuki ^a   Utsunomiya, Iwao ^a   Shudo, Koichi ^a  

^a Kawasaki   (Japan)

Author keywords

Drug discovery; Medicinal chemistry; Morpholine; Oxazolidinone; Piperazine; Seven membered heterocycle

Indexed keywords

ANTIINFECTIVE AGENT; DIAZEPINE DERIVATIVE; EPEREZOLID; FUNCTIONAL GROUP; LINEZOLID; METICILLIN; MORPHOLINE; OXAZOLIDINONE DERIVATIVE; TRIAZENE DERIVATIVE; UNCLASSIFIED DRUG; [1,2,5]OXADIAZEPANE; [1,2,5]TRIAZEPANE; AZEPINE DERIVATIVE;

ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; ARTICLE; DOSE RESPONSE; DRUG EFFICACY; DRUG SYNTHESIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; STAPHYLOCOCCUS INFECTION; ANIMAL; CHEMISTRY; DRUG DEVELOPMENT; DRUG EFFECTS; INTRAVENOUS DRUG ADMINISTRATION; MICROBIAL SENSITIVITY TEST; STAPHYLOCOCCAL INFECTIONS; SYNTHESIS;

ANIMALS; ANTI-BACTERIAL AGENTS; AZEPINES; DRUG DISCOVERY; INJECTIONS, INTRAVENOUS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICE; MICROBIAL SENSITIVITY TESTS; STAPHYLOCOCCAL INFECTIONS;

EID: 77954293200     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.58.1001     Document Type: Article

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