Structural identification of a new tri-p-coumaroylspermidine with serotonin transporter inhibition from safflower

Chemical and Pharmaceutical Bulletin

Volumn 58, Issue 7, 2010, Pages 950-952

  Zhao, Gang ^a,b   Qin, Guo Wei ^c   Gai, Yue ^a   Guo, Li He ^a,b  

^a Cell Star Bio Technologies Co Limited   (China)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^c SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Carthamus tinctorius; Transporter inhibitor; Tri p coumaroylspermidine

Indexed keywords

COUMARIN DERIVATIVE; N1,N5,N10 TRI 4 COUMAROYLSPERMIDINE; SEROTONIN; SEROTONIN TRANSPORTER; SPERMIDINE DERIVATIVE; UNCLASSIFIED DRUG; COUMARIC ACID; N1,N5,N10-TRIS(4-COUMAROYL)SPERMIDINE; SEROTONIN UPTAKE INHIBITOR; SPERMIDINE;

ANIMAL CELL; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHO CELL; DRUG ISOLATION; DRUG POTENCY; ELECTROSPRAY MASS SPECTROMETRY; HETERONUCLEAR MULTIPLE BOND CORRELATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SAFFLOWER; SEROTONIN UPTAKE; STRUCTURE ACTIVITY RELATION; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; CHO CELL LINE; CONFORMATION; CRICETULUS; HAMSTER; ISOLATION AND PURIFICATION; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ANIMALS; CARTHAMUS TINCTORIUS; CHO CELLS; COUMARIC ACIDS; CRICETINAE; CRICETULUS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEROTONIN UPTAKE INHIBITORS; SPERMIDINE;

EID: 77954278689     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.58.950     Document Type: Article

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