Genome-wide association studies: Does only size matter?

American Journal of Psychiatry

Volumn 167, Issue 7, 2010, Pages 741-744

  Schwartz, Sharon ^a   Susser, Ezra ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL ABUSE; ALCOHOLISM; CASE CONTROL STUDY; EDITORIAL; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC VARIABILITY; GENOME ANALYSIS; HERITABILITY; HUMAN; MOLECULAR GENETICS; PRIORITY JOURNAL; RISK FACTOR; SCHIZOPHRENIA;

GENOME-WIDE ASSOCIATION STUDY; HUMANS; SAMPLE SIZE; SCHIZOPHRENIA;

EID: 77954235796     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2010.10030465     Document Type: Editorial

References (9)

1. Akil H, Brenner S, Kandel E, Kendler KS, King MC, Scolnick E, Watson JD, Zoghbi HY: The future of psychiatric research: genomes and neural circuits. Science 2010; 327:1580-1581
2. Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, Cho JH, Guttmacher AE, Kong A, Kruglyak L, Mardis E, Rotimi CN, Slatkin M, Valle D, Whittemore AS, Boehnke M, Clark AG, Eichler EE, Gibson G, Haines JL, Mackay TFC, McCarroll SA, Visscher PM: Finding the missing heritability of complex diseases. Nature 2009; 461:747-753
3. McClellan J, King MC: Genetic heterogeneity in human disease. Cell 2010; 141:210-217
4. Sanders AR, Levinson DF, Duan J, Dennis JM, Li R, Kendler KS, Rice JP, Shi J, Mowry BJ, Amin F, Silverman JM, Buccola NG, Byerley WF, Black DW, Freedman R, Cloninger CR, Gejman PV: The Internet-based MGS2 control sample: self report of mental illness. Am J Psychiatry 2010; 167:854-865
5. Schwartz S, Link BG: The "well control" artefact in case/control studies of specific psychiatric disorders. Psychol Med 1989; 19:737-742
6. Kendler KS: The super-normal control group in psychiatric genetics: possible artifactual evidence for coaggregation. Psychiatr Genet 1990; 1:45-53
7. Rothman, KJ, Greenland S, Lash TL: Modern Epidemiology, 3rd ed. Philadelphia, Lippincott-Raven, 2008
8. Susser E, Schwartz S, Morabia A, Bromet EJ: Psychiatric Epidemiology: Searching for the Causes of Mental Disorders. New York, Oxford University Press, 2006
9. Shiboya A, Yoshida A: Frequency of atypical aldehyde dehydrogenase-2 gene in Japanese and Caucasians. Am J Hum Genet 1988; 43:741-743