Transfer of vanA from an Enterococcus Faecium isolate of chicken origin to a CC17 E. faecium isolate in the intestine of cephalosporin-treated mice

Journal of Antimicrobial Chemotherapy

Volumn 65, Issue 7, 2010, Pages 1534-1536

  Lester, Camilla H ^a   Hammerum, Anette M ^a  

^a STATENS SERUM INSTITUT   (Denmark)

Author keywords

Conjugation; Multilocus sequence typing; Vancomycin resistance

Indexed keywords

AMPICILLIN; BACTERIAL PROTEIN; CEFUROXIME; CEPHALOSPORIN; ERYTHROMYCIN; PROTEIN VANA; UNCLASSIFIED DRUG; VANCOMYCIN; ANTIINFECTIVE AGENT; CEPHALOSPORIN DERIVATIVE; LIGASE; VANA LIGASE, BACTERIA;

ANIMAL EXPERIMENT; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BACTERIUM ISOLATE; CHICKEN; ENTEROCOCCUS FAECIUM; FECES ANALYSIS; FEMALE; GENE CLUSTER; INTESTINE; LETTER; MOUSE; MULTILOCUS SEQUENCE TYPING; NONHUMAN; PROTEIN TRANSPORT; TREATMENT DURATION; VANCOMYCIN RESISTANT ENTEROCOCCUS; ANIMAL; BACTERIAL COUNT; BACTERIUM CONJUGATION; FECES; GENETICS; HORIZONTAL GENE TRANSFER; MICROBIOLOGY;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CARBON-OXYGEN LIGASES; CEPHALOSPORINS; CHICKENS; COLONY COUNT, MICROBIAL; CONJUGATION, GENETIC; ENTEROCOCCUS FAECIUM; FECES; FEMALE; GENE TRANSFER, HORIZONTAL; INTESTINES; MICE;

EID: 77954232279     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkq170     Document Type: Letter

References (6)

1. Sletvold H, Johnsen PJ, Simonsen GS et al. Comparative DNA analysis of two vanA plasmids from Enterococcus faecium strains isolated from poultry and a poultry farmer in Norway. Antimicrob Agents Chemother 2007; 51: 736-9.
2. Lester CH, Frimodt-Moller N, Sorensen TL et al. In vivo transfer of the vanA resistance gene from an Enterococcus faecium isolate of animal origin to an E. faecium isolate of human origin in the intestines of human volunteers. Antimicrob Agents Chemother 2006; 50: 596-9.
3. Dahl KH, Mater DD, Flores MJ et al. Transfer of plasmid and chromosomal glycopeptide resistance determinants occurs more readily in the digestive tract of mice than in vitro and exconjugants can persist stably in vivo in the absence of glycopeptide selection. J Antimicrob Chermother 2007; 59: 478-86.
4. Moubareck C, Bourgeois N, Courvalin P et al. Multiple antibiotic resistance gene transfer from animal to human enterococci in the digestive tract of gnotobiotic mice. Antimicrob Agents Chemother 2003; 47: 2993-6.
5. Rice LB, Lakticova V, Carias LL et al. Transferable capacity for gastrointestinal colonization in Enterococcus faecium in a mouse model. J Infect Dis 2009; 199: 342-9.
6. DANMAP 2008 - Use of Antimicrobial Agents and Occurrence of Antimicrobial Resistance in Bacteria From Food Animals, Foods and Humans in Denmark. http://www.danmap.org (9 February 2010, date last accessed).