Score-based adjustment for confounding by population stratification in genetic association studies

Genetic Epidemiology

Volumn 34, Issue 5, 2010, Pages 383-385

  Allen, Andrew ^a   Epstein, Michael P ^b   Satten, Glen A ^c  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE LOCUS; GENETIC ASSOCIATION; GENOTYPE; LETTER; POPULATION GENETICS; RISK FACTOR; SCORING SYSTEM;

BIAS (EPIDEMIOLOGY); CONFOUNDING FACTORS (EPIDEMIOLOGY); GENETIC ASSOCIATION STUDIES; GENOME, HUMAN; HUMANS; MODELS, GENETIC; MODELS, STATISTICAL; POPULATION GROUPS; PROPENSITY SCORE; RESEARCH DESIGN;

EID: 77954209603     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.20487     Document Type: Letter

References (13)

1. Allen AS, Satten GA. 2009a. Genome-wide association analysis of rheumatoid arthritis data via haplotype sharing. BMC Proceedings 3:S30.
2. Allen AS, Satten GA. 2009b. A novel haplotype-sharing approach for genome-wide case-control association studies implicates the calpastatin gene in Parkinson's disease. Genet Epidemiol 33:657-667.
3. Austin PC, Grootendorst P, Normand S-LT, Anderson GM. 2007. Conditioning on the propensity score can result in biased estimation of common measures of treatment effect: a Monte Carlo study. Stat Med 26:754-768. (Pubitemid 46206594)
4. Balding DJ, Nichols RA. 1995. A method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity. Genetica 96:3-12.
5. Epstein MP, Allen AS, Satten GA. 2007. A simple and improved correction for population stratification in case-control studies. Am J Hum Genet 80:921-930.
6. Fellay J, Shianna KV, Ge D, Colombo S, Ledergerber B, Weale M, Zhang K, Gumbs C, Castagna A, Cossarizza A, Cozzi-Lepri A, De Luca A, Easterbrook P, Francioli P, Mallal S, Martinez-Picado J, Miro JM, Obel N, Smith JP, Wyniger J, Descombes P, Antonarakis SE, Letvin NL, McMichael AJ, Haynes BF, Telenti A, Goldstein DB. 2007. A whole-genome association study of major determinants for host control of HIV-1. Science 5:944-947.
7. Joffe MM, Rosenbaum PR. 1999. Propensity scores. Am J Epidemiol 150:327-333.
8. Lunceford JK, Davidian M. 2004. Stratification and weighting via the propensity score in estimation of causal treatment effects: a comparative study. Stat Med 23:2937-2960. (Pubitemid 39200133)
9. Månsson R, Joffe MM, Sun W, Hennessy S. 2007. On the estimation and use of propensity scores in case-control and case-cohort studies. Am J Epidemiol 166:332-339. (Pubitemid 47216807)
10. McPeek MS, Abney M. 2008. Association testing with principal-components- based correction for population stratification [Abstract program number 58]. Presented at the annual meeting of The American Society of Human Genetics, November 13, 2008, Philadelphia, PA). Available from: http://www.ashg.org/ 2008meeting/abstracts/fulltext/
11. Miettinen O. 1976. Stratification by a multivariate confounder score. Am J Epidemiol 1976:609-620.
12. Pike MC, Anderson J, Day N. 1979. Some insights into Miettinen's confounder score approach to analysis of case-control data. 33:104-106.
13. Sarasua SM, Collins JS, Williamson DM, Satten GA, Allen AS. 2009. Effect of population stratification on the identification of significant SNPs in genome wide association studies. BMC Proceedings 3:S13.