Insights into bacterial 6-methylsalicylic acid synthase and its engineering to orsellinic acid synthase for spirotetronate generation

Chemistry and Biology

Volumn 17, Issue 5, 2010, Pages 495-503

  Ding, Wei ^a,b   Lei, Chun ^a   He, Qingli ^a   Zhang, Qinglin ^a   Bi, Yurong ^b   Liu, Wen ^a  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

^b LANZHOU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

6 METHYLSALICYLIC ACID; 6 METHYLSALICYLIC ACID SYNTHETASE; 6-METHYLSALICYLIC ACID; 6-METHYLSALICYLIC ACID SYNTHETASE; ACYLTRANSFERASE; AMINOGLYCOSIDE; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; CHLOROTHRICIN; LIGASE; MULTIENZYME COMPLEX; ORSELLINIC ACID; OXIDOREDUCTASE; RESORCINOL DERIVATIVE; SALICYLIC ACID DERIVATIVE;

ARTICLE; BIOSYNTHESIS; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; OXIDATION REDUCTION REACTION; PROTEIN ENGINEERING; PROTEIN TERTIARY STRUCTURE; STREPTOMYCES;

ACYLTRANSFERASES; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; LIGASES; MULTIENZYME COMPLEXES; OXIDATION-REDUCTION; OXIDOREDUCTASES; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; RESORCINOLS; SALICYLIC ACIDS; STREPTOMYCES;

BACTERIA (MICROORGANISMS); FUNGI;

EID: 77954203515     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2010.04.009     Document Type: Article

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