Conversion of (3 S,4 R)-tetrahydrodaidzein to (3 S)-equol by THD reductase: Proposed mechanism involving a radical intermediate

Biochemistry

Volumn 49, Issue 26, 2010, Pages 5582-5587

  Kim, Mihyang ^a   Marsh, E Neil G ^b   Kim, Soo Un ^c   Han, Jaehong ^a  

^a Chung Ang University   (South Korea)

^b UNIVERSITY OF MICHIGAN   (United States)

^c Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

DEUTERIUM RETENTION; H NMR SPECTROSCOPY; HYDROGEN ATOMS; OH GROUP; STEREOSPECIFIC REDUCTIONS;

BIOCHEMISTRY; DEUTERIUM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ATOMS;

(2,3,4 D 3) TETRAHYDRODAIDZEIN; CARBON; DAIDZEIN; DEUTERIUM; EQUOL; FLAVONOID; HYDROGEN; HYDROXIDE; RADICAL; UNCLASSIFIED DRUG; 4' O METHYL EQUOL; 4'-O-METHYL EQUOL; FREE RADICAL; ISOFLAVONE DERIVATIVE; OXIDOREDUCTASE; TETRAHYDRODAIDZEIN;

ARTICLE; DEUTERON NUCLEAR MAGNETIC RESONANCE; EGGERTHELLA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REDUCTION KINETICS; SYNTHESIS; ANAEROBIC BACTERIUM; BIOSYNTHESIS; CHEMICAL REACTION; CONFORMATION; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOISOMERISM;

EGGERTHELLA;

BACTERIA, ANAEROBIC; DEUTERIUM; FREE RADICALS; ISOFLAVONES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; ORGANIC CHEMISTRY PROCESSES; OXIDOREDUCTASES; STEREOISOMERISM;

EID: 77954203090     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100465y     Document Type: Article

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