CYP26B1 plays a major role in the regulation of all-trans-retinoic acid metabolism and signaling in human aortic smooth muscle cells

Journal of Vascular Research

Volumn 48, Issue 1, 2010, Pages 23-30

  Ocaya, Pauline Ajok ^a,d   Elmabsout, Ali Ateia ^a   Olofsson, Peder Stefan ^b,e   Törmä, Hans ^c   Gidlöf, Andreas Carl ^b   Sirsjö, Allan ^a  

^a ÖREBRO UNIVERSITY   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c UPPSALA UNIVERSITY   (Sweden)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

^e FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

All trans retinoic acid catabolism; CYP26 enzyme family; R115866 CYP26 inhibitor; Retinoids; Vascular smooth muscle cells

Indexed keywords

CYP26B1; CYTOCHROME; N [4 [2 ETHYL 1 (1H 1,2,4 TRIAZOL 1 YL)BUTYL]PHENYL] 2 BENZOTHIAZOLAMINE; RETINOIC ACID; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

AORTA; ARTICLE; BLOOD VESSEL INJURY; CELL PROLIFERATION; DNA SYNTHESIS INHIBITION; ENZYME ACTIVITY; GENE SILENCING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; VITAMIN METABOLISM;

AORTA; BENZOTHIAZOLES; CELL DIVISION; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MUSCLE, SMOOTH, VASCULAR; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRETINOIN; TRIAZOLES;

EID: 77954199236     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000317397     Document Type: Article

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