Elevation of systemic matrix metalloproteinases 2 and 7 and tissue inhibitor of metalloproteinase 2 in patients with a history of Achilles tendon rupture: Pilot study

British Journal of Sports Medicine

Volumn 44, Issue 9, 2010, Pages 669-672

  Pasternak, B ^a   Schepull, T ^a   Eliasson, P ^a   Aspenberg, P ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; MATRILYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ACHILLES TENDON; ADULT; ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYMOLOGY; FEMALE; HUMAN; INJURY; MALE; METABOLISM; MIDDLE AGED; PHYSIOLOGY; PILOT STUDY; PROSPECTIVE STUDY; RUPTURE; WOUND HEALING;

ACHILLES TENDON; ADULT; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 7; MIDDLE AGED; PILOT PROJECTS; PROSPECTIVE STUDIES; RUPTURE; TISSUE INHIBITOR OF METALLOPROTEINASE-2; WOUND HEALING;

EID: 77954190528     PISSN: 03063674     EISSN: 14730480     Source Type: Journal    
DOI: 10.1136/bjsm.2008.049411     Document Type: Article

References (23)

1. Riley G. The pathogenesis of tendinopathy. A molecular perspective. Rheumatology 2004;43:131-42.
2. Sharma P, Maffulli N. Tendon injury and tendinopathy: healing and repair. J Bone Joint Surg Am 2005;87:187-202. (Pubitemid 40094160)
3. de Mos M, van El B, De Groot J, et al. Achilles tendinosis: changes in biochemical composition and collagen turnover rate. Am J Sports Med 2007;35:1549-56.
4. Corps AN, Robinson AH, Movin T, et al. Increased expression of aggrecan and biglycan mRNA in Achilles tendinopathy. Rheumatology 2006;45:291-4.
5. Jones GC, Corps AN, Pennington CJ, et al. Expression profiling of metalloproteinases and tissue inhibitors of metalloproteinases in normal and degenerate human Achilles tendon. Arthritis Rheum 2006;54:832-42.
6. Kangas J, Pajala A, Ohtonen P, et al. Achilles tendon elongation after rupture repair: a randomized comparison of 2 postoperative regimens. Am J Sports Med 2007;35:59-64.
7. Leppilahti J, Forsman K, Puranen J, et al. Outcome and prognostic factors of Achilles rupture repair using a new scoring method. Clin Orthop Relat Res 1998:152-61.
8. Pajala A, Kangas J, Ohtonen P, et al. Rerupture and deep infection following treatment of total Achilles tendon rupture. J Bone Joint Surg Am 2002;84-A:2016-21.
9. Henle P, Zimmermann G, Weiss S. Matrix metalloproteinases and failed fracture healing. Bone 2005;37:791-8.
10. Stumpf M, Klinge U, Wilms A, et al. Changes of the extracellular matrix as a risk factor for anastomotic leakage after large bowel surgery. Surgery 2005;137:229-34.
11. Schepull T, Kvist J, Andersson C, et al. Mechanical properties during healing of Achilles tendon ruptures to predict final outcome. A pilot Roentgen stereophotogrammetric analysis in 10 patients. BMC Musculoskelet Disord 2007;8:116.
12. Thrailkill KM, Moreau CS, Cockrell G, et al. Physiological matrix metalloproteinase concentrations in serum during childhood and adolescence, using Luminex Multiplex technology. Clin Chem Lab Med 2005;43:1392-9.
13. Campbell MJ, Gardner MJ. Calculating confidence intervals for some nonparametric analyses. Br Med J (Clin Res Ed) 1988;296:1454-6.
14. Aroen A, Helgo D, Granlund OG, et al. Contralateral tendon rupture risk is increased in individuals with a previous Achilles tendon rupture. Scand J Med Sci Sports 2004;14:30-3.
15. Harvie P, Ostlere SJ, Teh J, et al. Genetic influences in the aetiology of tears of the rotator cuff. Sibling risk of a full-thickness tear. J Bone Joint Surg Br 2004;86:696-700.
16. September AV, Schwellnus MP, Collins M. Tendon and ligament injuries: the genetic component. Br J Sports Med 2007;41:241-6.
17. Malik MH, Jury F, Bayat A, et al. Genetic susceptibility to total hip arthroplasty failure: a preliminary study on the influence of matrix metalloproteinase 1, interleukin 6 polymorphisms and vitamin D receptor. Ann Rheum Dis 2007;66:1116-20.
18. Karousou E, Ronga M, Vigetti D, et al. Collagens, proteoglycans, MMP-2, MMP-9 and TIMPs in human Achilles tendon rupture. Clin Orthop Relat Res 2008;466:1577-82. Published Online First: 19 Apr. 2008.
19. de Hingh IH, Waas ET, Lomme RM, et al. Circulating matrix metalloproteinase-9 is transiently elevated after colorectal surgery. Int J Colorectal Dis 2004;19:446-50.
20. Shalabi A, Svensson L, Kristoffersen-Wiberg M, et al. Tendon injury and repair after core biopsies in chronic Achilles tendinosis evaluated by serial magnetic resonance imaging. Br J Sports Med 2004;38:606-12.
21. Kartus J, Movin T, Papadogiannakis N, et al. A radiographic and histologic evaluation of the patellar tendon after harvesting its central third. Am J Sports Med 2000;28:218-26.
22. Thrailkill K, Cockrell G, Simpson P, et al. Physiological matrix metalloproteinase (MMP) concentrations: comparison of serum and plasma specimens. Clin Chem Lab Med 2006;44:503-4.
23. Jung K. Preanalytical biases in measurement of matrix metalloproteinases and their tissue inhibitors in peripheral blood. J Rheumatol 2007;34:890-2.