D2-40 expression in primary scarring and nonscarring alopecia

American Journal of Dermatopathology

Volumn 32, Issue 5, 2010, Pages 427-431

  Mahalingam, Meera ^a   Hoang, Mai P ^b  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

alopecia; D2 40; nonscarring; scarring

Indexed keywords

MONOCLONAL ANTIBODY D2-40; PODOPLANIN; EPITOPE; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; PDPN PROTEIN, HUMAN;

ADOLESCENT; ADULT; AGED; ALOPECIA; ARTICLE; CHILD; CONTROLLED STUDY; GENETIC TRANSCRIPTION; HAIR FOLLICLE; HAIR ROOT; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCAR FORMATION; SCHOOL CHILD; BIOPSY; COMPARATIVE STUDY; DIAGNOSTIC USE; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PATHOLOGY; SCAR; STEM CELL; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALOPECIA; ANTIBODIES, MONOCLONAL; BIOPSY; CICATRIX; EPITOPES; HAIR FOLLICLE; HUMANS; IMMUNOHISTOCHEMISTRY; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; STEM CELLS; YOUNG ADULT; ANTIBODIES, MONOCLONAL, MURINE-DERIVED;

EID: 77954143231     PISSN: 01931091     EISSN: None     Source Type: Journal    
DOI: 10.1097/DAD.0b013e3181c34242     Document Type: Article

References (13)

1. Hoang MP, Keady M, Mahalingam M. Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia. Br J Dermatol. 2009;160:609-615.
2. Wetterwald A, Hoffstetter W, Cecchini MG, et al. Characterization and cloning of the E11 antigen, a marker expressed by rat osteoblasts and osteocytes. Bone. 1996;18:125-132.
3. Breiteneder-Geleff S, Matsui K, Soleiman A, et al. Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis. Am J Pathol. 1997;151:1141-1152.
4. Schacht V, Dadras SS, Johnson LA, et al. Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors. Am J Pathol. 2005;166: 913-921.
5. Liang H, Wu H, Giorgadze TA, et al. Podoplanin is a highly sensitive and specific marker to distinguish primary skin adnexal carcinomas from adenocarcinomas metastatic to skin. Am J Surg Pathol. 2007;31:304-310.
6. Gomaa AH, Yaar M, Bhawan J. Cutaneous immunoreactivity of D2-40 antibody beyond the lymphatics. Am J Dermatopathol. 2007;29:18-21.
7. Mobini N, Tam S, Kamino H. Possible role of the bulge region in the pathogenesis of inflammatory scarring alopecia: lichen planopilaris as the prototype. J Cutan Pathol. 2005;32:675-679.
8. Pozdnyakova O, Mahalingam M. Involvement of the bulge region in primary scarring alopecia. J Cutan Pathol. 2008;35:922-925.
9. Li L, Mignone J, Yang M, et al. Nestin expression in hair follicle sheath progenitor cells. Proc Natl Acad Sci U S A. 2003;100:9958-9961.
10. Erasmus JC, Braga VM. Rho GTPase activation by cell-cell adhesion. Methods Enzymol. 2006;406:402-415.
11. Durchdewald M, Guinea-Viniegra J, Haag D, et al. Podoplanin is a novel fos target gene in skin carcinogenesis. Cancer Res. 2008;68:6877-6883.
12. Bouillon R, Carmeliet G, Verlinden L, et al. Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev. 2008;29: 726-776.
13. Schrader M, Kahlen JP, Carlberg C. Functional characterization of a novel type of 1 alpha,25-dihydroxyvitamin D3 response element identified in the mouse c-fos promoter. Biochem Biophys Res Commun. 1997;230: 646-651.