Potential loss of methionine following extended storage of newborn screening samples prepared for tandem mass spectrometry analysis

Clinica Chimica Acta

Volumn 411, Issue 17-18, 2010, Pages 1284-1286

  Chace, Donald H ^a   Luo, Zuzheng ^b   De Jesús, Víctor R ^b   Haynes, Christopher A ^b   Hannon, W Harry ^b  

^a PEDIATRIX MEDICAL GROUP   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

Amino acids; Dried blood spots; Methionine; Newborn screening; Tandem mass spectrometry

Indexed keywords

METHIONINE; NITROGEN; POLYPROPYLENE; POLYSTYRENE;

AMINO ACID ANALYSIS; AMINO ACID LOSS; ARTICLE; BLOOD SAMPLING; CHEMICAL PROCEDURES; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; DEPLETION; HUMAN; MICROTITER PLATE ASSAY; MOLECULAR STABILITY; NEWBORN SCREENING; NITROGEN FIXATION; PRESERVATION AND STORAGE; PRIORITY JOURNAL; SIGNAL DETECTION; TANDEM MASS SPECTROMETRY; LABORATORY DIAGNOSIS; NEWBORN; PROCEDURES; STANDARD; URINE;

HUMANS; INFANT, NEWBORN; METHIONINE; NEONATAL SCREENING; REFERENCE STANDARDS; SPECIMEN HANDLING; TANDEM MASS SPECTROMETRY;

EID: 77954143145     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2010.05.011     Document Type: Article

References (4)

1. Chace D.H., Hillman S.L., Millington D.S., Kahler S.G., Adam B.W., Levy H.L. Rapid diagnosis of homocystinuria and other hypermethioninemias from newborns' blood spots by tandem mass spectrometry. Clin Chem 1996, 42:349-355.
2. Steinbach M., Clark R.H., Kelleher A.S., et al. Demographic and nutritional factors associated with prolonged cholestatic jaundice in the premature infant. J Perinatol 2007, 28:129-135.
3. Weisfeld-Adams J.D., Morrissey M.A., Kirmse B.M., et al. Newborn screening and early biochemical follow-up in combined methylmalonic aciduria and homocystinuria, cblC type, and utility of methionine as a secondary screening analyte. Mol Genet Metab 2010, 99:116-123.
4. De Jesus V.R., Chace D.H., Lim T.H., Mei J.V., Hannon W.H. Comparison of amino acids and acylcarnitines assay methods used in newborn screening assays by tandem mass spectrometry. Clin Chim Acta 2010, 411:684-689.