Safety of retransfusion of filtered shed blood in 1819 patients after total hip or knee arthroplasty

Transfusion Alternatives in Transfusion Medicine

Volumn 11, Issue 2, 2010, Pages 57-64

  Horstmann, Wieger G ^a   Slappendel, Robert ^b   Van Hellemondt, Gijs G ^c   Castelein, Rene M ^d   Verheyen, Cees C P M ^e  

^a Infection and Immunology   (Netherlands)

^b Perioperative Medicine Consultancy   (Netherlands)

^c SINT MAARTENSKLINIEK   (Netherlands)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e ISALA HOSPITAL   (Netherlands)

Author keywords

Adverse events; Hip knee arthroplasty; Safety; Transfusion autologous blood

Indexed keywords

ATROPINE; HEMOGLOBIN;

AORTA VALVE REGURGITATION; ARTICLE; ASYSTOLE; BLOOD AUTOTRANSFUSION; BLOOD CLOTTING; BLOOD TRANSFUSION REACTION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL TRIAL; DEEP VEIN THROMBOSIS; FEVER; HEART ATRIUM FIBRILLATION; HEART FAILURE; HEMOGLOBIN BLOOD LEVEL; HUMAN; LOW DRUG DOSE; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MULTICENTER STUDY; ORTHOPEDICS; POSTOPERATIVE CARE; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROSPECTIVE STUDY; PULMONARY HYPERTENSION; SHIVERING; SUCTION DRAINAGE; TOTAL HIP PROSTHESIS; TOTAL KNEE REPLACEMENT;

EID: 77954136631     PISSN: 12959022     EISSN: 1778428X     Source Type: Journal    
DOI: 10.1111/j.1778-428X.2010.01130.x     Document Type: Article

References (38)

1. Goodnough LT. Risks of blood transfusion. Crit Care Med 2003, 31:S678-S686.
2. Keating EM, Ritter MA. Transfusion options in total joint arthroplasty. J Arthroplasty 2002, 17:125-8.
3. Bierbaum BE, Callaghan JJ, Galante JO. An analysis of blood management in patients having a total hip or knee arthroplasty. J Bone Joint Surg Am 1999, 81:2-10.
4. Salido JA, Marin LA, Gomez LA, Zorrilla P, Martinez C. Preoperative hemoglobin levels and the need for transfusion after prosthetic hip and knee surgery: analysis of predictive factors. J Bone Joint Surg Am 2002, 84-A:216-20.
5. Lemos MJ, Healy WL. Blood transfusion in orthopaedic operations. J Bone Joint Surg Am 1996, 78:1260-70.
6. Keating EM, Meding JB. Perioperative blood management practices in elective orthopaedic surgery. J Am Acad Orthop Surg 2002, 10:393-400.
7. Newman JH, Bowers M, Murphy J. The clinical advantages of autologous transfusion. A randomized, controlled study after knee replacement. J Bone Joint Surg Br 1997, 79:630-2.
8. Slappendel R, Dirksen R, Weber EW, van der Schaaf DB. An algorithm to reduce allogenic red blood cell transfusions for major orthopedic surgery. Acta Orthop Scand 2003, 74:569-75.
9. Murphy P, Heal JM, Blumberg N. Infection or suspected infection after hip replacement surgery with autologous or homologous blood transfusions. Transfusion 1991, 31:212-17.
10. Blumberg N. Allogeneic transfusion and infection: economic and clinical implications. Semin Hematol 1997, 34:34-40.
11. Triulzi DJ, Vanek K, Ryan DH, Blumberg N. A clinical and immunologic study of blood transfusion and postoperative bacterial infection in spinal surgery. Transfusion 1992, 32:517-24.
12. Innerhofer P, Klingler A, Klimmer C, Fries D, Nussbaumer W. Risk for postoperative infection after transfusion of white blood cell-filtered allogeneic or autologous blood components in orthopedic patients undergoing primary arthroplasty. Transfusion 2005, 45:103-10.
13. Huet C, Salmi LR, Fergusson D. A meta-analysis of the effectiveness of cell salvage to minimize perioperative allogeneic blood transfusion in cardiac and orthopedic surgery. International Study of Perioperative Transfusion (ISPOT) Investigators. Anesth Analg 1999, 89:861-9.
14. Strumper D, Weber EW, Gielen-Wijffels S. Clinical efficacy of postoperative autologous transfusion of filtered shed blood in hip and knee arthroplasty. Transfusion 2004, 44:1567-71.
15. Moonen AFCM, Knoors NT, Van Os JJ, Verburg AD, Pilot P. Retransfusion of filtered shed blood in primary total hip and knee arthroplasty: a prospective randomized clinical trial. Transfusion 2007, 47:379-84.
16. Ayers DC, Murray DG, Duerr DM. Blood salvage after total hip arthroplasty. J Bone Joint Surg Am 1995, 77:1347-51.
17. Henderson MS, Newman JH. Postoperative blood salvage and reinfusion in total knee arthroplasty. J Arthroplasty 1996, 11:356.
18. Grosvenor D, Goyal V, Goodman S. Efficacy of postoperative blood salvage following total hip arthroplasty in patients with and without deposited autologous units. J Bone Joint Surg Am 2000, 82-A:951-4.
19. Healy WL, Pfeifer BA, Kurtz SR. Evaluation of autologous shed blood for autotransfusion after orthopaedic surgery. Clin Orthop Relat Res 1994, 299:53-9.
20. Gharehbaghian A, Haque KM, Truman C. Effect of autologous salvaged blood on postoperative natural killer cell precursor frequency. Lancet 2004, 363:1025-30.
21. Iorwerth A, Wilson C, Topley N, Pallister I. Neutrophil activity in total knee replacement: implications in preventing post-arthroplasty infection. Knee 2003, 10:111-13.
22. Muñoz M, Muñoz E, Navajas A. Impact of postoperative unwashed shed blood retrieved after total knee arthroplasty on endotoxin-stimulated tumor necrosis factor alpha release in vitro. Anesthesiology 2006, 104:267-72.
23. Muñoz M, Cobos A, Campos A. Post-operative unwashed shed blood transfusion does not modify the cellular immune response to surgery for total knee replacement. Acta Anaesthesiol Scand 2006, 50:443-50.
24. Muñoz M, Cobos A, Campos A. Impact of postoperative shed blood transfusion, with or without leucocyte reduction, on acute-phase response to surgery for total knee replacement. Acta Anaesthesiol Scand 2005, 49:1182-90.
25. Faris PM, Ritter MA, Keating EM, Valeri CR. Unwashed filtered shed blood collected after knee and hip arthroplasties. A source of autologous red blood cells. J Bone Joint Surg Am 1991, 73:1169-78.
26. Handel M, Winkler J, Hornlein RF. Increased interleukin-6 in collected drainage blood after total knee arthroplasty: an association with febrile reactions during retransfusion. Acta Orthop Scand 2001, 72:270-2.
27. Martin JW, Whiteside LA, Milliano MT, Reedy ME. Postoperative blood retrieval and transfusion in cementless total knee arthroplasty. J Arthroplasty 1992, 7:205-10.
28. Muñoz M, Ariza D, Florez A, Campos A. Reinfusion drains reduce postoperative transfusion requirements after primary total knee replacement surgery. Transfus Med 2008, 18:269-71.
29. Muñoz M, Kühlmorgen B, Ariza D. Which patients are more likely to benefit from postoperative shed blood salvage after unilateral total knee replacement? An analysis of 581 consecutive procedures. Vox Sang 2007, 92:136-41.
30. Hansen E, Hansen MP. Reasons against the retransfusion of unwashed wound blood. Transfusion 2004, 44:45S-53S.
31. Allogenic Blood Transfusion Guideline. http://www.cbo.nl/Downloads/95/bloedkaart.pdf, The Dutch Institute for Healthcare Improvement (CBO), Accessed at
32. Arnestad JP, Bengtsson A, Bengtson JP. Formation of cytokines by retransfusion of shed whole blood. Br J Anaesth 1994, 72:422-5.
33. Avall A, Hyllner M, Bengtson JP, Carlsson L, Bengtsson A. Greater increase in cytokine concentration after salvage with filtered whole blood than with washed red cells, but no difference in postoperative hemoglobin recovery. Transfusion 1999, 39:271-6.
34. Bengtsson A, Avall A, Hyllner M, Bengtson JP. Formation of complement split products and proinflammatory cytokines by reinfusion of shed autologous blood. Toxicol Lett 1998, 100-101:129-33.
35. Andres BM, Taub DD, Gurkan I, Wenz JF. Postoperative fever after total knee arthroplasty: the role of cytokines. Clin Orthop Relat Res 2003, 415:221-31.
36. Shaw JA, Chung R. Febrile response after knee and hip arthroplasty. Clin Orthop Relat Res 1999, 367:181-9.
37. Kennedy JG, Rodgers WB, Zurakowski D. Pyrexia after total knee replacement. A cause for concern? Am J Orthop 1997, 26:549-52.
38. Guinn S, Castro FP, Garcia R, Barrack RL. Fever following total knee arthroplasty. Am J Knee Surg 1999, 12:161-4.