메뉴 건너뛰기




Volumn 183, Issue 8, 2009, Pages 5013-5022

Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2α during inflammatory conditions

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN L; CYTOTOXIC T LYMPHOCYTE ANTIGEN 2ALPHA; GAMMA INTERFERON; LYMPHOCYTE ANTIGEN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 77954136126     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0901623     Document Type: Article
Times cited : (53)

References (46)
  • 1
    • 0027055536 scopus 로고
    • Immunogenetic aspects of clinical and experimental uveitis
    • Caspi, R. R. 1992. Immunogenetic aspects of clinical and experimental uveitis. Reg. Immunol. 4: 321-330.
    • (1992) Reg. Immunol. , vol.4 , pp. 321-330
    • Caspi, R.R.1
  • 4
    • 34250157039 scopus 로고    scopus 로고
    • Minimally activated CD8 autoreactive T cells specific for IRBP express a high level of Foxp3 and are functionally suppressive
    • Peng, Y., H. Shao, Y. Ke, P. Zhang, G. Han, H. J. Kaplan, and D. Sun. 2007. Minimally activated CD8 autoreactive T cells specific for IRBP express a high level of Foxp3 and are functionally suppressive. Invest. Ophthalmol. Vis. Sci. 48: 2178-2184.
    • (2007) Invest. Ophthalmol. Vis. Sci. , vol.48 , pp. 2178-2184
    • Peng, Y.1    Shao, H.2    Ke, Y.3    Zhang, P.4    Han, G.5    Kaplan, H.J.6    Sun, D.7
  • 6
    • 53149143166 scopus 로고    scopus 로고
    • Ocular regulatory T cells distinguish monophasic from recurrent autoimmune uveitis
    • Ke, Y., G. Jiang, D. Sun, H. J. Kaplan, and H. Shao. 2008. Ocular regulatory T cells distinguish monophasic from recurrent autoimmune uveitis. Invest. Ophthalmol. Vis. Sci. 49: 3999-4007.
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 3999-4007
    • Ke, Y.1    Jiang, G.2    Sun, D.3    Kaplan, H.J.4    Shao, H.5
  • 7
    • 0036254611 scopus 로고    scopus 로고
    • Novel cysteine proteinase inhibitors homologous to the proregions of cysteine proteinases
    • Yamamoto, Y., M. Kurata, S. Watabe, R. Murakami, and S. Y. Takahashi. 2002. Novel cysteine proteinase inhibitors homologous to the proregions of cysteine proteinases. Curr. Protein Pept. Sci. 3: 231-238.
    • (2002) Curr. Protein Pept. Sci. , vol.3 , pp. 231-238
    • Yamamoto, Y.1    Kurata, M.2    Watabe, S.3    Murakami, R.4    Takahashi, S.Y.5
  • 9
    • 0027985152 scopus 로고
    • Inhibition of cathepsin L-like cysteine proteases by cytotoxic T-lymphocyte antigen-2β
    • Delaria, K., L. Fiorentino, L. Wallace, P. Tamburini, E. Brownell, and D. Muller. 1994. Inhibition of cathepsin L-like cysteine proteases by cytotoxic T-lymphocyte antigen-2β. J. Biol. Chem. 269: 25172-25177.
    • (1994) J. Biol. Chem. , vol.269 , pp. 25172-25177
    • Delaria, K.1    Fiorentino, L.2    Wallace, L.3    Tamburini, P.4    Brownell, E.5    Muller, D.6
  • 16
    • 0037815115 scopus 로고    scopus 로고
    • Iris pigment epithelium expressing CD86 (B7-2) directly suppresses T cell activation in vitro via binding to cytotoxic T lymphocyte-associated antigen 4
    • Sugita, S., and J. W. Streilein. 2003. Iris pigment epithelium expressing CD86 (B7-2) directly suppresses T cell activation in vitro via binding to cytotoxic T lymphocyte-associated antigen 4. J. Exp. Med. 198: 161-171.
    • (2003) J. Exp. Med. , vol.198 , pp. 161-171
    • Sugita, S.1    Streilein, J.W.2
  • 17
    • 1642310491 scopus 로고    scopus 로고
    • + iris pigment epithelial cells express their own B7-2 to achieve global suppression of T cell activation
    • + iris pigment epithelial cells express their own B7-2 to achieve global suppression of T cell activation. J. Immunol. 172: 4184-4194.
    • (2004) J. Immunol. , vol.172 , pp. 4184-4194
    • Sugita, S.1    Ng, T.F.2    Schwartzkopff, J.3    Streilein, J.W.4
  • 19
    • 33750482270 scopus 로고    scopus 로고
    • Retinal and ciliary body pigment epithelium suppress activation of T lymphocytes via transforming growth factor β
    • Sugita, S., Y. Futagami, S. B. Smith, H. Naggar, and M. Mochizuki. 2006. Retinal and ciliary body pigment epithelium suppress activation of T lymphocytes via transforming growth factor β. Exp. Eye Res. 83: 1459-1471.
    • (2006) Exp. Eye Res. , vol.83 , pp. 1459-1471
    • Sugita, S.1    Futagami, Y.2    Smith, S.B.3    Naggar, H.4    Mochizuki, M.5
  • 22
    • 0033989076 scopus 로고    scopus 로고
    • Identification of a new epitope of human IRBP that induces autoimmune uveoretinitis in mice of the H-2b haplotype
    • Avichezer, D., P. B. Silver, C. C. Chan, B. Wiggert, and R. R. Caspi. 2000. Identification of a new epitope of human IRBP that induces autoimmune uveoretinitis in mice of the H-2b haplotype. Invest. Ophthalmol. Vis. Sci. 41: 127-131.
    • (2000) Invest. Ophthalmol. Vis. Sci. , vol.41 , pp. 127-131
    • Avichezer, D.1    Silver, P.B.2    Chan, C.C.3    Wiggert, B.4    Caspi, R.R.5
  • 23
    • 0030757911 scopus 로고    scopus 로고
    • Oral tolerance in a murine model of relapsing experimental autoimmune uveoretinitis (EAU): Induction of protective tolerance in primed animals
    • Thurau, S. R., C. C. Chan, R. B. Nussenblatt, and R. R. Caspi. 1997. Oral tolerance in a murine model of relapsing experimental autoimmune uveoretinitis (EAU): induction of protective tolerance in primed animals. Clin. Exp. Immunol. 109: 370-376.
    • (1997) Clin. Exp. Immunol. , vol.109 , pp. 370-376
    • Thurau, S.R.1    Chan, C.C.2    Nussenblatt, R.B.3    Caspi, R.R.4
  • 24
    • 0027213710 scopus 로고
    • Pleiotropic effects of transforming growth factor-β on cells of the immune system
    • Ruscetti, F., L. Varesio, A. Ochoa, and J. Ortaldo. 1993. Pleiotropic effects of transforming growth factor-β on cells of the immune system. Ann. NY Acad. Sci. 685: 488-500.
    • (1993) Ann. NY Acad. Sci. , vol.685 , pp. 488-500
    • Ruscetti, F.1    Varesio, L.2    Ochoa, A.3    Ortaldo, J.4
  • 25
    • 0028180315 scopus 로고
    • The TGF-β superfamily: New members, new receptors, and new genetic tests of function in different organisms
    • Kingsley, D. M. 1994. The TGF-β superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev. 8: 133-146. (Pubitemid 24044338)
    • (1994) Genes and Development , vol.8 , Issue.2 , pp. 133-146
    • Kingsley, D.M.1
  • 28
    • 0037364804 scopus 로고    scopus 로고
    • Natural versus adaptive regulatory T cells
    • Bluestone, J. A., and A. K. Abbas. 2003. Natural versus adaptive regulatory T cells. Nat. Rev. Immunol. 3: 253-257.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 253-257
    • Bluestone, J.A.1    Abbas, A.K.2
  • 29
    • 0035186416 scopus 로고    scopus 로고
    • Induction and mechanism of action of transforming growth factor-β-secreting Th3 regulatory cells
    • Weiner, H. L. 2001. Induction and mechanism of action of transforming growth factor-β-secreting Th3 regulatory cells. Immunol. Rev. 182: 207-214.
    • (2001) Immunol. Rev. , vol.182 , pp. 207-214
    • Weiner, H.L.1
  • 30
    • 2442484053 scopus 로고    scopus 로고
    • + regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • + regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22: 531-562.
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 32
    • 25844504653 scopus 로고    scopus 로고
    • Developmental regulation of Foxp3 expression during ontogeny
    • Fontenot, J. D., J. L. Dooley, A. G. Farr, and A. Y. Rudensky. 2005. Developmental regulation of Foxp3 expression during ontogeny. J. Exp. Med. 202: 901-906.
    • (2005) J. Exp. Med. , vol.202 , pp. 901-906
    • Fontenot, J.D.1    Dooley, J.L.2    Farr, A.G.3    Rudensky, A.Y.4
  • 35
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
    • Tivol, E. A., F. Borriello, A. N. Schweitzer, W. P. Lynch, J. A. Bluestone, and A. H. Sharpe. 1995. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 3: 541-547.
    • (1995) Immunity , vol.3 , pp. 541-547
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, A.N.3    Lynch, W.P.4    Bluestone, J.A.5    Sharpe, A.H.6
  • 41
    • 0034600070 scopus 로고    scopus 로고
    • Disruption of T cell homeostasis in mice expressing a T cell-specific dominant negative transforming growth factor βII receptor
    • Lucas, P. J., S. J. Kim, S. J. Melby, and R. E. Gress. 2000. Disruption of T cell homeostasis in mice expressing a T cell-specific dominant negative transforming growth factor βII receptor. J. Exp. Med. 191: 1187-1196.
    • (2000) J. Exp. Med. , vol.191 , pp. 1187-1196
    • Lucas, P.J.1    Kim, S.J.2    Melby, S.J.3    Gress, R.E.4
  • 42
    • 0034131557 scopus 로고    scopus 로고
    • Abrogation of TGFβ signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
    • Gorelik, L., and R. A. Flavell. 2000. Abrogation of TGFβ signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity 12: 171-181. (Pubitemid 30398631)
    • (2000) Immunity , vol.12 , Issue.2 , pp. 171-181
    • Gorelik, L.1    Flavell, R.A.2
  • 43
    • 0033104503 scopus 로고    scopus 로고
    • Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-β
    • Yang, X., J. J. Letterio, R. J. Lechleider, L. Chen, R. Hayman, H. Gu, A. B. Roberts, and C. Deng. 1999. Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-β. EMBO J. 18: 1280-1291.
    • (1999) EMBO J. , vol.18 , pp. 1280-1291
    • Yang, X.1    Letterio, J.J.2    Lechleider, R.J.3    Chen, L.4    Hayman, R.5    Gu, H.6    Roberts, A.B.7    Deng, C.8
  • 44
    • 35448982671 scopus 로고    scopus 로고
    • + T cells induced by iris pigment epithelial cells display regulatory phenotype and acquire regulatory functions
    • + T cells induced by iris pigment epithelial cells display regulatory phenotype and acquire regulatory functions. Exp. Eye Res. 85: 626-636.
    • (2007) Exp. Eye Res. , vol.85 , pp. 626-636
    • Sugita, S.1    Futagami, Y.2    Horie, S.3    Mochizuki, M.4
  • 45
    • 0023105185 scopus 로고
    • Efficient synthetic method for ethyl+-(2S,3S)-3-[(S)-3-methyl-1-(3- methylbutylcarbamoyl) butylcarbamoyl]-2-oxiranecarb oxylate (EST), a new inhibitor of cysteine proteinases
    • Tamai, M., C. Yokoo, M. Murata, K. Oguma, K. Sota, E. Sato, and Y. Kanaoka. 1987. Efficient synthetic method for ethyl+-(2S,3S)-3-[(S)-3-methyl-1- (3-methylbutylcarbamoyl) butylcarbamoyl]-2-oxiranecarb oxylate (EST), a new inhibitor of cysteine proteinases. Chem. Pharm. Bull. 35: 1098-1104.
    • (1987) Chem. Pharm. Bull. , vol.35 , pp. 1098-1104
    • Tamai, M.1    Yokoo, C.2    Murata, M.3    Oguma, K.4    Sota, K.5    Sato, E.6    Kanaoka, Y.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.