Management of red cell alloimmunisation in pregnancy: The non-invasive monitoring of the disease

Prenatal Diagnosis

Volumn 30, Issue 7, 2010, Pages 668-673

  Illanes, Sebastian ^a   Soothill, Peter ^b  

^a UNIVERSIDAD DE LOS ANDES   (Chile)

^b ST MICHAEL'S HOSPITAL   (United Kingdom)

Author keywords

Cell free fetal DNA; Doppler of middle cerebral artery; Fetal RHD genotype; Intrauterine transfusion

Indexed keywords

DNA; RHESUS D ANTIBODY; RHESUS D ANTIGEN; BLOOD GROUP RHESUS SYSTEM;

ALLOIMMUNIZATION; ANEMIA; CELL FREE SYSTEM; DOPPLER ECHOGRAPHY; ERYTHROCYTE; FOLLOW UP; GENOTYPE; HUMAN; INTRAUTERINE BLOOD TRANSFUSION; MATERNAL PLASMA; NEWBORN HEMOLYTIC DISEASE; NON INVASIVE PROCEDURE; PREGNANCY; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; BLOOD; BLOOD GROUP RHESUS SYSTEM; ERYTHROBLASTOSIS, FETAL; FEMALE; GENETICS; IMMUNOLOGY; NEWBORN;

ERYTHROBLASTOSIS, FETAL; ERYTHROCYTES; FEMALE; GENOTYPE; HUMANS; INFANT, NEWBORN; PREGNANCY; RH-HR BLOOD-GROUP SYSTEM; RHO(D) IMMUNE GLOBULIN;

EID: 77954131755     PISSN: 01973851     EISSN: 10970223     Source Type: Journal    
DOI: 10.1002/pd.2551     Document Type: Review

References (63)

1. Abdel-Fattah SA, Shefras J, Kyle PM, Cairns P, Hunter A, Soothill PW. 2005. Reassuring fetal middle cerebral artery doppler velocimetry in alloimmunised pregnancies: neonatal outcomes without invasive procedures. Fetal Diagn Ther 20(5): 341-345.
2. Abdel-Fattah SA, Soothill PW, Carroll SG, Kyle PM. 2002. Middle cerebral artery Doppler for the prediction of fetal anaemia in cases without hydrops: a practical approach. Br J Radiol 75(897): 726-730.
3. Alberry MS, Maddocks DG, Hadi MA, et al. 2009. Quantification of cell free fetal DNA in maternal plasma in normal pregnancies and in pregnancies with placental dysfunction. Am J Obstet Gynecol 200(1): 98.e1-98.e6.
4. Arnholdt H, Meisel F, Fandrey K, Lohrs U. 1991. Proliferation of villous trophoblast of the human placenta in normal and abnormal pregnancies. Virchows Arch B Cell Pathol Incl Mol Pathol 60: 365-372.
5. Avent ND. 2008. RHD genotyping from maternal plasma: guidelines and technical challenges. Methods Mol Biol 444: 185-201;
6. Avent ND. 2009. Large-scale blood group genotyping: clinical implications. Br J Haematol 144(1): 3-13;
7. Avent ND, Finning KM, Martin PG, Soothill PW. 2000. Prenatal determination of fetal blood group status. Vox Sang 78(Suppl 2): 155-162.
8. Bang J, Bock JE, Trolle D. 1982. Ultrasound guided fetal intravenous transfusion for severe rhesus haemolytic disease. BMJ 284: 373-374. (Pubitemid 12171693)
9. Bartha JL, Illanes S, Abdel-Fattah S, Hunter A, Denbow M, Soothill PW. 2005. Comparison of different reference values of fetal blood flow velocity in the middle cerebral artery for predicting fetal anemia. Ultrasound Obstet Gynecol 25(4): 335-340.
10. Bennett PR, Le Van Kim C, Colin Y, et al. 1993. Prenatal determination of fetal RhD type by DNA amplification. N Engl J Med 329(9): 607-610.
11. Bowman JM. 1978. The management of Rh isoimmunization. Obstet Gynecol 52: 1-16.
12. Chitty LS, van der Schoot CE, Hahn S, Avent ND. 2008. SAFE - the Special Non-invasive Advances in Fetal and Neonatal Evaluation Network: aims and achievements. Prenat Diagn 28: 83-88.
13. Daniels G, Finning K, Martin P, Massey E. 2009. Noninvasive prenatal diagnosis of fetal blood group phenotypes: current practice and future prospects. Prenat Diagn 29(2): 101-107.
14. Daniels G, Finning K, Martin P, Soothill P. 2004. Fetal blood group genotyping from DNA from maternal plasma: an important advance in the management and prevention of haemolytic disease of the fetus and newborn. Vox Sang 4: 225-232.
15. De Vore GR, Mayden K, Tortora M, Berkowitz RL, Hobbins JC. 1981. Dilation of the fetal umbilical vein in rhesus hemolytic anemia: a predictor of severe disease. Am J Obstet Gynecol 141: 464-466.
16. Finning K, Martin P, Daniels G. 2004. A clinical service in the UK to predict fetal Rh (Rhesus) D blood group using free fetal DNA in maternal plasma. Ann N Y Acad Sci 1022: 119-123.
17. Finning K, Martin PG, Soothill PW, Avent ND. 2002. Prediction of fetal D status from maternal plasma: introduction of a new noninvasive fetal RHD genotyping service. Transfusion 42: 1079-1085.
18. Finning K, Martin P, Summers J, Daniels G. 2007. Fetal genotyping for the K (Kell) and Rh C, c, and E blood groups on cell-free fetal DNA in maternal plasma. Transfusion 11: 2126-2133.
19. Formigli L, Papucci L, Tani A, et al. 2000. Aponecrosis: morphological and biochemical exploration of a syncretic process of cell death sharing apoptosis and necrosis. J Cell Physiol 182: 41-49.
20. Geifman-Holtzman O, Grotegut CA, Gaughan JP. 2006. Diagnostic accuracy of non-invasive fetal Rh genotyping from maternal blood - a meta-analysis. Am J Obstet Gynecol 4: 1163-1173.
21. Geifman-Holtzman O, Grotegut CA, Gaughan JP, Holtzman EJ, Floro C, Hernandez E. 2009. Non-invasive fetal RhCE genotyping from maternal blood. BJOG 116(2): 144-151.
22. Hecher K, Snijders R, Campbell S, Nicolaides K. 1995. Fetal venous, arterial, and intracardiac blood flows in red blood cell isoimmunisation. Obstet Gynecol 85: 122-128.
23. Huppertz B, Kadyrov M, Kingdom JC. 2006. Apoptosis and its role in the trophoblast. Am J Obstet Gynecol 195: 29-39.
24. Illanes S, Parra M, Serra R, et al. 2009. Increased free fetal DNA levels in early pregnancy plasma of women who subsequently develop preeclampsia and intrauterine growth restriction. Prenat Diagn 29(12): 1118-1112.
25. Illanes S, Soothill P. 2009. The non-invasive approach for the management of haemolytic disease of the fetus and newborn. Current aspects of the clinical management of haemolytic disease of the newborn and fetus. Expert Rev Hematol 5: 577-582.
26. Illanes S, Soothill PW. 2006. Fetal therapy. In Progress in Obstetrics and Gynaecology, Studd J (ed.). Elsevier: UK; 65-78.
27. Kirkinen P, Jouppila P, Eik-Nes S. 1981. Umbilical venous flow as indicator of fetal anaemia. Lancet 2(1): 1004-1005.
28. Legler TJ, Liu Z, Mavrou A, et al. 2007. Workshop report on the extraction of fetal DNA from maternal plasma. Prenat Diagn 27: 824-829.
29. Li Y, Finning K, Daniels G, Hahn S, Zhong X, Holzgreve W. 2008. Non-invasive genotyping fetal Kell blood group (KEL1) using cell-free fetal DNA in maternal plasma by MALDI-TOF mass spectrometry. Prenat Diagn 28(3): 203-208.
30. Liley AW. 1963. Intrauterine transfusion of fetus in haemolytic disease. BMJ 2: 1107-1109.
31. Lo YM, Corbetta N, Chamberlain PF, et al. 1997. Presence of fetal DNA in maternal plasma and serum. Lancet 350: 485-487.
32. Lo YM, Tein MSC, Lau TK, et al. 1998. Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis. Am J Hum Genet 62: 768-775.
33. Maddocks DG, Alberry MS, Attilakos G, et al. 2009. The SAFE project: towards non-invasive prenatal diagnosis. Biochem Soc Trans 37(Pt 2): 460-465.
34. Mari G, Adrignolo A, Abuhamad AZ, et al. 1995. Diagnosis of fetal anemia with Doppler ultrasound in the pregnancy complicated by maternal blood group immunization. Ultrasound Obstet Gynecol 5(6): 400-405.
35. Mari G, Deter RL, Carpenter RL, et al. 2000. Non-invasive diagnosis by Doppler ultrasonography of fetal anemia due to maternal red-cell alloimmunization. N Engl J Med 342: 9-14.
36. Mari G, Rahman F, Olofsson P, Ozcan T, Copel JA. 1997. Increase of fetal hematocrit decreases the middle cerebral artery peak systolic velocity in pregnancies complicated by rhesus alloimmunization. J Matern Fetal Med 6: 206-208.
37. McGlone L, Simpson JH, Scott-Lang C, Cameron AD, Brennand J. 2009. Short term outcomes following intrauterine transfusion in Scotland. Arch Dis Child Fetal Neonatal Ed [Epub ahead of print].
38. Müller SP, Bartels I, Stein W, et al. 2008. The determination of the fetal D status from maternal plasma for decision making on Rh prophylaxis is feasible. Transfusion 11: 2292-2301.
39. Murray JC, Karp LE, Williamson RA, Cheng EY, Luthy DA. 1983. Rh isoimmunization related to amniocentesis. Am J Med Genet 6: 527-534.
40. Nanal R, Kyle P, Soothill PW. 2003. A classification of pregnancy losses after invasive prenatal diagnostic procedures: an approach to allow comparison of units with a different case mix. Prenat Diagn 23: 488-492.
41. Nicolaides KH, Fontanarosa M, Gabbe SG, Rodeck CH. 1988a. Failure of ultrasonographic parameters to predict the severity of fetal anemia in rhesus isoimmunization. Am J Obstet Gynecol 158: 920-926.
42. Nicolaides KH, Rodeck CH. 1992. Maternal serum anti-D antibody concentration and assessment of rhesus isoimmunisation. Br Med J 304: 1155-1156.
43. Nicolaides KH, Soothill PW, Clewell WH, Rodeck CH, Mibashan RS, Campbell S. 1988b. Fetal haemoglobin measurement in the assessment of red cell isoimmunisation. Lancet 1: 1073-1075.
44. Nicolaides KH, Warenski JC, Rodeck CH. 1985. The relationship of fetal plasma protein concentration and hemoglobin level to the development of hydrops in rhesus isoimmunization. Am J Obstet Gynecol 152: 341-344.
45. Oepkes D, Brand R, Vandenbussche FP, Meerman RH, Kanhai HHH. 1994. The use of ultrasonography and Doppler in the prediction of fetal haemolytic anaemia: a multivariate analysis. Br J Obstet Gynaecol 101: 680-684. (Pubitemid 24251521)
46. Oepkes D, Seaward PG, Vandenbussche FP, et al.; DIAMOND Study Group. 2006. Doppler ultrasonography versus amniocentesis to predict fetal anemia. N Engl J Med 355(2): 156-164.
47. Queenan JT. 1982. Current management of the Rh-sensitized patient. Clin Obstet Gynecol 25: 293-301.
48. Rightmire DA, Nicolaides KH, Rodeck CH, Campbell S. 1986. Fetal blood velocities in Rh isoimmunization: relationship to gestational age and to fetal hematocrit. Obstet Gynecol 68(2): 233-236. (Pubitemid 16038623)
49. Rodeck CH, Kemp JR, Holman CA, Whitmore CA, Karnicki J, Austin MA. 1981. Direct intravascular fetal blood transfusion by fetoscopy in severe Rhesus isoimmunisation. Lancet 1: 625-627.
50. Socol ML, MacGregor SN, Pielet BW, Tamura RK, Sabbagha RE. 1987. Percutaneous umbilical transfusion in severe rhesus isoimmunization: resolution of fetal hydrops. Am J Obstet Gynecol 157: 1369-1375.
51. Soothill PW, Nicolaides KH, Rodeck CH. 1987a. Effect of anaemia on fetal acid-base status. Br J Obstet Gynaecol 94(9): 880-883.
52. Soothill PW, Nicolaides KH, Rodeck CH, Clewell WH, Lindridge J. 1987b. Relationship of fetal hemoglobin and oxygen content to lactate concentration in Rh isoimmunized pregnancies. Obstet Gynecol 69: 268-267.
53. Steiner H, Schaffer H, Spitzer D, Batka M, Graf AH, Staudach A. 1995. The relationship between peak velocity in the fetal descending aorta and hematocrit in rhesus isoimmunization. Obstet Gynecol 85(5 Pt 1): 659-662.
54. Szczepura A, Bonsel G, Krauth C, Osipenko L, Haverkamp A. 2008. Fetal RHD typing: is fetal RHD typing in all RhD negative women cost effective? BMJ 336(7650): 906-906.
55. Tabor A, Bang J, Nørgaard-Pedersen B. 1987. Feto-maternal haemorrhage associated with genetic amniocentesis: results of a randomized trial. Br J Obstet Gynecol 94: 528-534. (Pubitemid 17077761)
56. Thein AT, Soothill P. 1998. Antenatal invasive therapy. Eur J Pediatr 157(Suppl 1): S2-S6.
57. Ubarniak S, 2002. The clinical application of anti-D prophilaxis. In Alloimmune Disorders of Pregnancy: Anaemia, Thrombocytopenia and Neutropenia in the Fetus and Newborn, Hadley A, Soothill P (eds). Cambridge University Press: Cambridge; 97-121.
58. Van der Schoot CE, Soussan AA, Koelewijn J, Bonsel G, Paget-Christiaens LG, de Haas M. 2006. Non-invasive antenatal RHD typing. Transfus Clin Biol 13: 53-57.
59. Van der Schoot CE, Tax GH, Rijnders RJ, de Haas M, Christiaens GC. 2003. Prenatal typing of Rh and Kell blood group system antigens: the edge of a watershed. Transfus Med Rev 17: 31-44.
60. Van Dijk BA, Dororen MC, Overbeeke MA. 1995. Red cell antibodies in pregnancy: there is no 'critical titre'. Transfus Med 5: 199-202.
61. Van Kamp IL, Klumper FJCM, Bakkum RSLA. 2001. The severity of immune fetal hydrops is predictive for fetal outcome after intrauterine treatment. Am J Obstet Gynecol 185: 668-673.
62. Vyas S, Nicolaides KH, Campbell S. 1990. Doppler examination of the middle cerebral artery in anemic fetuses. Am J Obstet Gynecol 162: 1066-1068. (Pubitemid 20155434)
63. Wataganara T, Bianchi DW. 2004. Fetal cell-free nucleic acids in the maternal circulation: new clinical applications. Ann N Y Acad Sci 1022: 90-99.