|
|
|
Volumn 13, Issue 7, 2010, Pages 457-466
|
|
The 'retro-design' concept for novel kinase inhibitors
a
|
|
Author keywords
Binding kinetics; fragment based lead generation; imatinib; residence time; retro design; sorafenib; type II kinase inhibitor
|
|
Indexed keywords
2 [4 (2 DIMETHYLAMINOETHOXY)PHENYL] 4 (1 HYDROXYIMINO 5 INDANYL) 5 (4 PYRIDINYL) 1H IMIDAZOLE;
CHIR 265;
DASATINIB;
ERLOTINIB;
FASUDIL;
GEFITINIB;
IMATINIB;
LAPATINIB;
NILOTINIB;
PHOSPHOTRANSFERASE INHIBITOR;
SORAFENIB;
SUNITINIB;
TANDUTINIB;
PEPTIDE;
PEPTIDE LIBRARY;
PROTEIN BINDING;
PROTEIN KINASE;
PROTEIN KINASE INHIBITOR;
BINDING KINETICS;
DRUG ACTIVITY;
DRUG BINDING;
DRUG DESIGN;
DRUG SELECTIVITY;
DRUG TARGETING;
HUMAN;
REVIEW;
ANIMAL;
CHEMISTRY;
COMPUTER AIDED DESIGN;
ENZYME ACTIVE SITE;
KINETICS;
METABOLISM;
PEPTIDE LIBRARY;
PHARMACEUTICS;
PROCEDURES;
PROTEIN CONFORMATION;
ANIMALS;
CATALYTIC DOMAIN;
COMPUTER-AIDED DESIGN;
DRUG DESIGN;
HUMANS;
KINETICS;
PEPTIDE LIBRARY;
PEPTIDES;
PROTEIN BINDING;
PROTEIN CONFORMATION;
PROTEIN KINASE INHIBITORS;
PROTEIN KINASES;
TECHNOLOGY, PHARMACEUTICAL;
|
|
EID: 77954127254
PISSN: 13697056
EISSN: None
Source Type: Journal
DOI: None Document Type: Review |
|
Times cited : (5)
|
|
References (0)
|
