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Volumn 24, Issue 3, 2010, Pages 287-291

Gypenosides causes DNA damage and inhibits expression of DNA repair genes of human oral cancer SAS cells

Author keywords

DNA damage; DNA repair gene; Gypenosides; Human oral cancer SAS cells

Indexed keywords

ATM PROTEIN; ATR PROTEIN; BRCA1 PROTEIN; DNA DEPENDENT PROTEIN KINASE; GYPENOSIDE; MESSENGER RNA; PROTEIN P53;

EID: 77954123059     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (24)

References (23)
  • 1
    • 33746210066 scopus 로고    scopus 로고
    • Gypenosides protect primary cultures of rat cortical cells against oxidative neurotoxicity
    • Shang L, Liu J, Zhu Q, Zhao L, Feng Y, Wang X, Cao W and Xin H: Gypenosides protect primary cultures of rat cortical cells against oxidative neurotoxicity. Brain Res 1102(1): 163-174, 2006.
    • (2006) Brain Res , vol.1102 , Issue.1 , pp. 163-174
    • Shang, L.1    Liu, J.2    Zhu, Q.3    Zhao, L.4    Feng, Y.5    Wang, X.6    Cao, W.7    Xin, H.8
  • 2
    • 22844437873 scopus 로고    scopus 로고
    • Cardiovascular effects of the aqueous extract of Gynostemma pentaphyllum Makino
    • Circosta C, De Pasquale R and Occhiuto F: Cardiovascular effects of the aqueous extract of Gynostemma pentaphyllum Makino. Phytomedicine 12(9): 638-643, 2005.
    • (2005) Phytomedicine , vol.12 , Issue.9 , pp. 638-643
    • Circosta, C.1    De Pasquale, R.2    Occhiuto, F.3
  • 3
    • 0041663626 scopus 로고    scopus 로고
    • Gypenosides derived from Gynostemma pentaphyllum suppress NO synthesis in murine macrophages by inhibiting iNOS enzymatic activity and attenuating NF-kappaB-mediated iNOS protein expression
    • Aktan F, Henness S, Roufogalis BD and Ammit AJ: Gypenosides derived from Gynostemma pentaphyllum suppress NO synthesis in murine macrophages by inhibiting iNOS enzymatic activity and attenuating NF-kappaB-mediated iNOS protein expression. Nitric Oxide 8(4): 235-242, 2003.
    • (2003) Nitric Oxide , vol.8 , Issue.4 , pp. 235-242
    • Aktan, F.1    Henness, S.2    Roufogalis, B.D.3    Ammit, A.J.4
  • 4
    • 0037179551 scopus 로고    scopus 로고
    • Regulation of Bcl-2 family molecules and activation of caspase cascade involved in gypenosides-induced apoptosis in human hepatoma cells
    • Wang QF, Chen JC, Hsieh SJ, Cheng CC and Hsu SL: Regulation of Bcl-2 family molecules and activation of caspase cascade involved in gypenosides-induced apoptosis in human hepatoma cells. Cancer Lett 183(2): 169-178, 2002.
    • (2002) Cancer Lett , vol.183 , Issue.2 , pp. 169-178
    • Wang, Q.F.1    Chen, J.C.2    Hsieh, S.J.3    Cheng, C.C.4    Hsu, S.L.5
  • 5
    • 0030223645 scopus 로고    scopus 로고
    • The effect of Gynostemma pentaphyllum mak (GP) on carcinogenesis of the golden hamster cheek pouch induced by DMBA
    • Zhou Z, Wang Y and Zhou Y: The effect of Gynostemma pentaphyllum mak (GP) on carcinogenesis of the golden hamster cheek pouch induced by DMBA. Chin J Stomatol 31(5): 267-270, 1996.
    • (1996) Chin J Stomatol , vol.31 , Issue.5 , pp. 267-270
    • Zhou, Z.1    Wang, Y.2    Zhou, Y.3
  • 6
    • 0029590318 scopus 로고
    • A preliminary observation of preventive and blocking effect of Gynostemma pentaphyllum (Thunb) Makino on esophageal cancer in rats
    • Wang C, Wang X, Li Y, Deng S, Jiang Y and Yue L: A preliminary observation of preventive and blocking effect of Gynostemma pentaphyllum (Thunb) Makino on esophageal cancer in rats. J West China Univ Medi Sci 26(4): 430-432, 1995.
    • (1995) J West China Univ Medi Sci , vol.26 , Issue.4 , pp. 430-432
    • Wang, C.1    Wang, X.2    Li, Y.3    Deng, S.4    Jiang, Y.5    Yue, L.6
  • 7
    • 33845959908 scopus 로고    scopus 로고
    • Gypenosides induced apoptosis in human colon cancer cells through the mitochondria-dependent pathways and activation of caspase-3
    • Chen JC, Lu KW, Lee JH, Yeh CC and Chung JG: Gypenosides induced apoptosis in human colon cancer cells through the mitochondria-dependent pathways and activation of caspase-3. Anticancer Res 26(6B): 4313-4326, 2006. (Pubitemid 46031504)
    • (2006) Anticancer Research , vol.26 , Issue.6 B , pp. 4313-4326
    • Chen, J.-C.1    Lu, K.-W.2    Lee, J.-H.3    Yeh, C.-C.4    Chung, J.-G.5
  • 9
    • 0019617451 scopus 로고
    • DNA damage as the primary cause of aging
    • Gensler HL and Bernstein H: DNA damage as the primary cause of aging. Q Rev Biol 56(3): 279-303, 1981.
    • (1981) Q Rev Biol , vol.56 , Issue.3 , pp. 279-303
    • Gensler, H.L.1    Bernstein, H.2
  • 10
    • 0029084744 scopus 로고
    • The detection and measurement of base and nucleotide excision repair in cell-free extracts of the yeast Saccharomyces cerevisiae
    • Wang Z, Wu X and Friedberg EC: The detection and measurement of base and nucleotide excision repair in cell-free extracts of the yeast Saccharomyces cerevisiae. Methods 7(2): 177-186 1995.
    • (1995) Methods , vol.7 , Issue.2 , pp. 177-186
    • Wang, Z.1    Wu, X.2    Friedberg, E.C.3
  • 12
    • 54049145466 scopus 로고    scopus 로고
    • DNA damage and endoplasmic reticulum stress mediated curcumin-induced cell cycle arrest and apoptosis in human lung carcinoma A-549 cells through the activation caspases cascade- and mitochondrial-dependent pathway
    • Lin SS, Huang HP, Yang JS, Wu JY, Hsia TC, Lin CC, Lin CW, Kuo CL, Gibson Wood W and Chung JG: DNA damage and endoplasmic reticulum stress mediated curcumin-induced cell cycle arrest and apoptosis in human lung carcinoma A-549 cells through the activation caspases cascade- and mitochondrial-dependent pathway. Cancer Lett 272(1): 77-90, 2008.
    • (2008) Cancer Lett , vol.272 , Issue.1 , pp. 77-90
    • Lin, S.S.1    Huang, H.P.2    Yang, J.S.3    Wu, J.Y.4    Hsia, T.C.5    Lin, C.C.6    Lin, C.W.7    Kuo, C.L.8    Gibson Wood, W.9    Chung, J.G.10
  • 13
    • 34547774260 scopus 로고    scopus 로고
    • Crude extracts of Euchresta formosana radix induce cytotoxicity and apoptosis in human hepatocellular carcinoma cell line (Hep3B)
    • Hsu SC, Kuo CL, Lin JP, Lee JH, Lin CC, Su CC, Lin HJ and Chung JG: Crude extracts of Euchresta formosana radix induce cytotoxicity and apoptosis in human hepatocellular carcinoma cell line (Hep3B). Anticancer Res 27(4B): 2415-2426, 2007.
    • (2007) Anticancer Res , vol.27 , Issue.4 B , pp. 2415-2426
    • Hsu, S.C.1    Kuo, C.L.2    Lin, J.P.3    Lee, J.H.4    Lin, C.C.5    Su, C.C.6    Lin, H.J.7    Chung, J.G.8
  • 14
    • 34250654965 scopus 로고    scopus 로고
    • The comet assay: A method to measure DNA damage in individual cells
    • Olive PL and Banath JP: The comet assay: a method to measure DNA damage in individual cells. Nat Protoc 1(1): 23-29, 2006.
    • (2006) Nat Protoc , vol.1 , Issue.1 , pp. 23-29
    • Olive, P.L.1    Banath, J.P.2
  • 16
    • 0028910894 scopus 로고
    • The single-cell gel electrophoresis assay for induced DNA damage (comet assay): Measurement of tail length and moment
    • Ashby J, Tinwell H, Lefevre PA and Browne MA: The single-cell gel electrophoresis assay for induced DNA damage (comet assay): measurement of tail length and moment. Mutagenesis 10(2): 85-90, 1995.
    • (1995) Mutagenesis , vol.10 , Issue.2 , pp. 85-90
    • Ashby, J.1    Tinwell, H.2    Lefevre, P.A.3    Browne, M.A.4
  • 18
    • 0025360746 scopus 로고
    • Cytotoxic and cytoprotective activities of curcumin. Effects on paracetamol-induced cytotoxicity, lipid peroxidation and glutathione depletion in rat hepatocytes
    • Donatus IA, Sardjoko and Vermeulen NP: Cytotoxic and cytoprotective activities of curcumin. Effects on paracetamol-induced cytotoxicity, lipid peroxidation and glutathione depletion in rat hepatocytes. Biochem Pharmacol 39(12): 1869-1875, 1990.
    • (1990) Biochem Pharmacol , vol.39 , Issue.12 , pp. 1869-1875
    • Sardjoko, D.I.A.1    Vermeulen, N.P.2
  • 21
    • 0025618481 scopus 로고
    • The single cell gel assay: A sensitive technique for evaluating intercellular differences in DNA damage and repair
    • Tice RR, Andrews PW and Singh NP: The single cell gel assay: a sensitive technique for evaluating intercellular differences in DNA damage and repair. Basic Life Sci 53: 291-301, 1990.
    • (1990) Basic Life Sci , vol.53 , pp. 291-301
    • Tice, R.R.1    Andrews, P.W.2    Singh, N.P.3
  • 22
    • 0025305451 scopus 로고
    • Detection of etoposide resistance by measuring DNA damage in individual Chinese hamster cells
    • Olive PL, Banath JP and Durand RE: Detection of etoposide resistance by measuring DNA damage in individual Chinese hamster cells. J Natl Cancer Inst 82(9): 779-783, 1990.
    • (1990) J Natl Cancer Inst , vol.82 , Issue.9 , pp. 779-783
    • Olive, P.L.1    Banath, J.P.2    Durand, R.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.