Identification of cancer autoantigens in serum: Toward diagnosticprognostic testing?

Molecular Diagnosis and Therapy

Volumn 14, Issue 3, 2010, Pages 149-154

  Casal, J Ignacio ^a   Barderas, Rodrigo ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

antigens, diagnostic use; autoantibodies; biomarkers; cancer; cancer autoantigens; cancer diagnosis; cancer therapy; diagnostics; protein microarrays

Indexed keywords

AUTOANTIGEN; DASATINIB; IMATINIB; TUMOR ANTIGEN;

AMINO ACID SEQUENCE; ANTIBODY RESPONSE; CANCER IMMUNOTHERAPY; CANCER LOCALIZATION; CANCER THERAPY; CROSS REACTION; HUMAN; IMMUNE SYSTEM; OPEN READING FRAME; OVARY CANCER; PRIORITY JOURNAL; PROGNOSIS; PROTEIN MICROARRAY; PROTEIN STRUCTURE; PROTEOMICS; REPRODUCIBILITY; REVIEW; SENSITIVITY AND SPECIFICITY;

ANTIGENS, NEOPLASM; AUTOANTIGENS; HUMANS; INDIVIDUALIZED MEDICINE; MOLECULAR DIAGNOSTIC TECHNIQUES; NEOPLASMS; PROGNOSIS;

EID: 77954113498     PISSN: 11771062     EISSN: 11792000     Source Type: Journal    
DOI: 10.2165/11534760-000000000-00000     Document Type: Review

References (35)

1. Anderson KS, LaBaer J. The sentinel within: exploiting the immune system for cancer biomarkers. J Proteome Res 2005 Jul-Aug; 4 (4): 1123-1133
2. Shiku H, Takahashi T, Resnick LA, et al. Cell surface antigens of human malignant melanoma: III. Recognition of autoantibodies with unusual characteristics. J Exp Med 1977 Mar 1; 145 (3): 784-789
3. Chatterjee M, Mohapatra S, Ionan A, et al. Diagnostic markers of ovarian cancer by high-throughput antigen cloning and detection on arrays. Cancer Res 2006 Jan 15; 66 (2): 1181-1190
4. Hudson ME, Pozdnyakova I, Haines K, et al. Identification of differentially expressed proteins in ovarian cancer using high-density protein microarrays. Proc Natl Acad Sci U S A 2007 Oct 30; 104 (44): 17494-17499
5. Anderson KS, Ramachandran N, Wong J, et al. Application of protein microarrays for multiplexed detection of antibodies to tumor antigens in breast cancer. J Proteome Res 2008 Apr; 7 (4): 1490-1499
6. Babel I, Barderas R, Diaz-Uriarte R, et al. Identification of tumor-associated autoantigens for the diagnosis of colorectal cancer in serum using high density protein microarrays. Mol Cell Proteomics 2009 Oct; 8 (10): 2382-2395
7. Bouwman K, Qiu J, Zhou H, et al. Microarrays of tumor cell derived proteins uncover a distinct pattern of prostate cancer serum immunoreactivity. Proteomics 2003 Nov; 3 (11): 2200-2207
8. Bradford TJ, Wang X, Chinnaiyan AM. Cancer immunomics: using autoantibody signatures in the early detection of prostate cancer. Urol Oncol 2006 May-Jun; 24 (3): 237-242
9. Wang X, Yu J, Sreekumar A, et al. Autoantibody signatures in prostate cancer. N Engl J Med 2005 Sep 22; 353 (12): 1224-1235
10. Sahin U, Tureci O, Schmitt H, et al. Human neoplasms elicit multiple specific immune responses in the autologous host. Proc Natl Acad SciUSA1995 Dec 5; 92 (25): 11810-11813
11. Chen YT, Scanlan MJ, Sahin U, et al. A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening. Proc Natl Acad Sci U S A 1997 Mar 4; 94 (5): 1914-1918
12. Jongeneel V. Towards a cancer immunome database. Cancer Immun 2001 Mar 30; 1: 3
13. Klade CS, Voss T,Krystek E, et al. Identification of tumor antigens in renal cell carcinoma by serological proteome analysis. Proteomics 2001 Jul; 1 (7): 890-898
14. Hong SH, Misek DE, Wang H, et al. An autoantibody-mediated immune response to calreticulin isoforms in pancreatic cancer. Cancer Res 2004 Aug 1; 64 (15): 5504-5510
15. Chen G, Gharib TG, Huang CC, et al. Proteomic analysis of lung adenocarcinoma: identification of a highly expressed set of proteins in tumors. Clin Cancer Res 2002 Jul; 8 (7): 2298-2305
16. Lueking A, HornM, EickhoffH, et al. Protein microarrays for gene expression and antibody screening. Anal Biochem 1999 May 15; 270 (1): 103-111
17. Qiu J, Madoz-Gurpide J, Misek DE, et al. Development of natural protein microarrays for diagnosing cancer based on an antibody response to tumor antigens. J Proteome Res 2004 Mar-Apr; 3 (2): 261-267
18. Zhong L, Hidalgo GE, Stromberg AJ, et al. Using protein microarray as a diagnostic assay for non-small cell lung cancer. Am J Respir Crit Care Med 2005 Nov 15; 172 (10): 1308-1314
19. Mintz PJ, Kim J, Do KA, et al. Fingerprinting the circulating repertoire of antibodies from cancer patients. Nat Biotechnol 2003 Jan; 21 (1): 57-63
20. Bussow K, Nordhoff E, Lubbert C, et al. A human cDNA library for highthroughput protein expression screening. Genomics 2000 Apr 1; 65 (1): 1-8
21. Ramachandran N, Hainsworth E, Bhullar B, et al. Self-assembling protein microarrays. Science 2004 Jul 2; 305 (5680): 86-90
22. Ramachandran N, Raphael JV, Hainsworth E, et al. Next-generation highdensity self-assembling functional protein arrays. Nat Methods 2008 Jun; 5 (6): 535-538
23. Tan EM, Zhang J. Autoantibodies to tumor-associated antigens: reporters from the immune system. Immunol Rev 2008 Apr; 222: 328-340
24. DeLeo AB, Jay G, Appella E, et al. Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse. Proc Natl Acad Sci U S A 1979 May; 76 (5): 2420-2424
25. Anderson KS, Wong J, Vitonis A, et al. p53 autoantibodies as potential detection and prognostic biomarkers in serous ovarian cancer. Cancer Epidemiol Biomarkers Prev 2010 Mar; 19 (3): 859-868
26. Chen G, Wang X, Yu J, et al. Autoantibody profiles reveal ubiquilin 1 as a humoral immune response target in lung adenocarcinoma. Cancer Res 2007 Apr 1; 67 (7): 3461-3467
27. Qiu J, Choi G, Li L, et al. Occurrence of autoantibodies to annexin I, 14-3-3 theta andLAMR1 in prediagnostic lung cancer sera. JClin Oncol 2008 Nov 1; 26 (31): 5060-5066
28. Koziol JA, Zhang JY,Casiano CA, et al. Recursive partitioning as an approach to selection of immune markers for tumor diagnosis. Clin Cancer Res 2003 Nov 1; 9 (14): 5120-5126
29. Taylor BS, PalM, Yu J, et al. Humoral response profiling reveals pathways to prostate cancer progression. Mol Cell Proteomics 2008 Mar; 7 (3): 600-611
30. Gnjatic S, Ritter E, Buchler MW, et al. Seromic profiling of ovarian and pancreatic cancer. Proc Natl Acad Sci U S A 2010 Mar 16; 107 (11): 5088-5093
31. Scanlan MJ,Welt S, Gordon CM, et al. Cancer-related serological recognition of human colon cancer: identification of potential diagnostic and immunotherapeutic targets. Cancer Res 2002 Jul 15; 62 (14): 4041-4047
32. Zhang JY, Casiano CA, Peng XX, et al. Enhancement of antibody detection in cancer using panel of recombinant tumor-associated antigens. Cancer Epidemiol Biomarkers Prev 2003 Feb; 12 (2): 136-143
33. Bei R, Masuelli L, Palumbo C, et al. A common repertoire of autoantibodies is shared by cancer and autoimmune disease patients: inflammation in their induction and impact on tumor growth. Cancer Lett 2009 Aug 18; 281 (1): 8-23
34. Segal NH, Parsons DW, Peggs KS, et al. Epitope landscape in breast and colorectal cancer. Cancer Res 2008 Feb 1; 68 (3): 889-892
35. Chatterjee M, Draghici S, Tainsky MA. Immunotheranostics: breaking tolerance in immunotherapy using tumor autoantigens identified on protein microarrays. Curr Opin Drug Discov Devel 2006 May; 9 (3): 380-385