Pharmacological activities on Ephedra nebrodensis Tineo

Natural Product Research

Volumn 24, Issue 12, 2010, Pages 1115-1124

  Ballero, Mauro ^a   Foddis, Caterina ^a   Sanna, Cinzia ^a   Scartezzini, Paolo ^b   Poli, Ferruccio ^b   Petitto, Valentina ^c   Serafini, Mauro ^c   Stanzione, Alessandra ^c   Bianco, Armandodoriano ^c   Serilli, Anna Maria ^c   Spina, Liliana ^a   Longoni, Rosanna ^a   Kasture, Sanjay ^d  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d MGV's Pharmacy College   (India)

Author keywords

adaptogenic; antioxidant; Ephedra nebrodensis; pharmacological activities

Indexed keywords

ACETONE; ALCOHOL; ALKALOID; AMPHETAMINE; BUTYLATED HYDROXYANISOLE; CARRAGEENAN; DIAZEPAM; DIPHENHYDRAMINE; EPHEDRA EXTRACT; EPHEDRA NEBRODENSIS EXTRACT; HISTAMINE; IBUPROFEN; UNCLASSIFIED DRUG; ANALGESIC AGENT; ANTIHISTAMINIC AGENT; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIHISTAMINIC ACTIVITY; ANTIHYPERTENSIVE ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG DOSE COMPARISON; EOSINOPHIL COUNT; EOSINOPHILIA; EPHEDRA; EPHEDRA NEBRODENSIS; GUINEA PIG; IC 50; LEUKOCYTE COUNT; LEUKOCYTOSIS; LOCOMOTION; MALE; MOUSE; NONHUMAN; PAIN; PAW EDEMA; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; REARING; SMOOTH MUSCLE CONTRACTION; STEREOTYPY; WRITHING TEST; ANIMAL; CHEMISTRY; DRUG EFFECTS; MEDICINAL PLANT; MOTOR ACTIVITY; SPRAGUE DAWLEY RAT;

EPHEDRA NEBRODENSIS;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; EPHEDRA; GUINEA PIGS; HISTAMINE ANTAGONISTS; MALE; MICE; MOTOR ACTIVITY; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77954105833     PISSN: 14786419     EISSN: 14786427     Source Type: Journal    
DOI: 10.1080/14786410802680902     Document Type: Article

References (29)

1. Brekhman, I.I., & Dardymov, I.V. (1969). New substances from plant origin which increase nonspecific resistance. Annual Review of Pharmacology, 9, 419-430.
2. Bruneton, J (1995). Pharmacognosy, phytochemistry, medicinal plants. Paris: Lavoisier. Carboni, S. (1940). Sulle efedre della Sardegna. La Ricerca Scientifica, XVIII, 754-757.
3. Cottiglia, F., Bonsignore, L., Casu, L., Deidda, D., Pompei, R., Casu, M., et al. (2005). Phenolic constituent from Ephedra nebrodensis. Natural Product Research, 19(2), 117-123.
4. Erdem, Y., & Kupeli, E. (2002). Berberis crataegina DC. root exhibits potent anti-inflammatory, analgesic and febrifuge effects in mice and rats. Journal of Ethnopharmacology, 79, 237-248.
5. Farnsworth N.R. (Ed). (1995) NAPRALERT database. Chicago: University of Illinois at Chicago.
6. Flordal, P.A., & Svensson, J. (1992). Hemostatic effects of ephedrine. Thrombosis Research, 68, 295-302.
7. Goodman, L.S., & Gilman, A. (1993). Goodman and Gilman's pharmacological basis of therapeutics (8th ed., pp. 213-214). New York: MacMillan.
8. Gunnar, G.-S., & Ian, D.S. (1994). Biosynthetic route to the Ephedra alkaloids. Journal of American Society, 116, 6195-6200.
9. Harada, M., & Nishimura, M. (1991). Contribution of alkaloid fraction to pressor and hyperglycemic effect of crude Ephedra extract in dogs. Journal of Pharmacobio-Dynamics, 4, 691-699.
10. Hikino, H., Ogata, K., Konno, C, & Sato, S. (1983a). Structure of feruloylhistamine, a hypotensive principle of Ephedra roots. Planta Medica, 48(6), 108-110. (Pubitemid 13007458)
11. Hikino, H., Ogata, K., Konno, C., & Sato, S. (1983b). Hypotensive actions of ephedradines, macrocyclic spermine alkaloids of Ephedra roots. Planta Medica, 48(4), 290-293.
12. Kasahara, Y., Hikino, H., Tsurufuji, S., Watanabe, M., & Ohuchi, K. (1985). Antiinflammatory actions of ephedrines in acute inflammations. Planta Medica, 51, 325-331.
13. 1H-NMR spectroscopy and principal component analysis. Chemical & Pharmaceutical Bulletin, 53, 105-109.
14. 1H-NMR. Chemical and Pharmaceutical Bulletin, 51, 1382-1385.
15. Kim, T.H., Yang, K.S., Hwang, E.Z., & Park, S.B. (1991). Effect of Ephedra herba on the immune response in mice. Korean Journal of Pharmacognosy, 22, 183-191.
16. Konno, C. (1979). Ephedroxane, anti-inflammatory principle of Ephedra herbs. Phytochemistry, 18, 697-698.
17. Leung, A.Y., Foster, S. (2000). Enciclopedia delle piante medicinali utilizzate negli alimenti, nei farmaci e nei cosmetici. Roma: Aporie.
18. Lida, M., Miyazaki, I., Tanaka, K., Kabuto, H., Ichikawa, E., & Ogawa, N. (1990). Dopamine D2 receptor mediated antioxidant and neuroprotective effect of ropinirole, a dopamine agonist. Brain Research, 838, 51-59.
19. Lohr, J.B., Kuczenski, R, & Niculescu, A.B. (2003). Oxidative mechanisms and tardive dyskinesia. CNS Drugs, 17, 47-62.
20. Matsui, T., Suzuki, Y., Yamashita, K., Yoshimaru, T., Suzuki-Karasaki, M., Hayakawa, S., et al. (2000). Diphenyleneiodonium prevents reactive oxygen species generation, tyrosine phos-phorylation, and histamine release in RBL-2H3 cells. Biochemical and Biophysical Research Communications, 276, 742-748.
21. Munhall, A.C., & Johnson, S.W. (2006). Dopamine-mediated actions of ephedrine in the rat Substantia nigra. Brain Research, 1069, 96-103.
22. Nag Chaudhari, A.K., & Lahiri, S.C. (1974). Use of goat trachea for an isolated tracheal chain preparation. Indian Journal of Pharmacology, 6, 149-151.
23. Pignatti, S. (1982). Flora d'Italia. I, II, III. Edagricole: Bologna.
24. 2 extracts of Helichrysum italicum (Roth) Don (Asteraceae). Pharmaceutical Biology, 41, 379-383.
25. Spina, L., Longoni, R., Mulas, A., Chang, K.J., & Di Chiara, G. (1998). Dopamine-dependent behavioural stimulation by non-peptide delta opioids BW373U86 and SNC 80: 1. Locomotion, rearing and stereotypies in intact rats. Behavioural Pharmacology, 9, 1-8. (Pubitemid 28098661)
26. Van Hellemont, J. (1986). Compendium de phytothérapie. APB: Bruxelles.
27. Wang, M., Li, J., Rangarajan, M., Shao, Y., LaVoie, E.J., Huang, T.C., et al. (1998). Antioxidative phenolic compounds from sage (Salvia officinalis). Journal of Agricultural and Food Chemistry, 46, 4869-4873.
28. Winter, C.W., Risley, E.A., & Nuss, G.W. (1962). Carraggeenin-induced edema in hind paw of the rat as an assay for antiinflammatory drugs. Proceedings of the Society for Experimental Biology and Medicine, 111, 544-547.
29. World Health Organization. (1989). Medicinal plants of China (WHO Regional Publications Western Pacific Series, No. 2). Manila: WHO.