Computed tomography-guided high-dose-rate brachytherapy in hepatocellular carcinoma: Safety, efficacy, and effect on survival

International Journal of Radiation Oncology Biology Physics

Volumn 78, Issue 1, 2010, Pages 172-179

  Mohnike, Konrad ^a   Wieners, Gero ^a   Schwartz, Franziska ^a   Seidensticker, Max ^a   Pech, MacIej ^a   Ruehl, Ricarda ^a   Wust, Peter ^b   Lopez Hänninen, Enrique ^c   Gademann, Günther ^a   Peters, Nils ^a   Berg, Thomas ^b   Malfertheiner, Peter ^a   Ricke, Jens ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c MARTIN LUTHER KRANKENHAUS   (Germany)

Author keywords

Hepatocellular carcinoma; Liver malignancies; Local ablation; Radiotherapy

Indexed keywords

BENEFICIAL EFFECTS; BRACHYTHERAPY; COMPUTED TOMOGRAPHY; CONTROL GROUPS; COX REGRESSION; FETOPROTEIN; HEPATOCELLULAR CARCINOMA; HIGH RATE; HIGH-DOSE-RATE BRACHYTHERAPY; IRIDIUM-192; KAPLAN-MEIER; LOCAL ABLATION; LOCAL CONTROL; LOCAL RECURRENCE; LOCAL TUMOR CONTROL; MULTIFOCAL; OVERALL SURVIVAL; STATISTICAL ANALYSIS;

ABLATION; IRIDIUM; LIVER; ONCOLOGY; RADIOTHERAPY;

COMPUTERIZED TOMOGRAPHY;

ALPHA FETOPROTEIN; IRIDIUM 192;

ADULT; AGED; ARTICLE; BRACHYTHERAPY; CANCER CONTROL; CANCER GROWTH; CANCER SURVIVAL; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMAN; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; RADIATION DOSE; STOMACH ULCER; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; ALPHA-FETOPROTEINS; BRACHYTHERAPY; CARCINOMA, HEPATOCELLULAR; DISEASE PROGRESSION; FEMALE; HUMANS; IRIDIUM RADIOISOTOPES; LIVER NEOPLASMS; MALE; MATCHED-PAIR ANALYSIS; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROSPECTIVE STUDIES; RADIATION INJURIES; RADIOTHERAPY DOSAGE; RADIOTHERAPY, COMPUTER-ASSISTED; TOMOGRAPHY, X-RAY COMPUTED; TUMOR BURDEN;

EID: 77954089553     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.07.1700     Document Type: Article

References (45)

1. D. Jaeck, P. Bachellier, and E. Oussoultzoglou Surgical resection of hepatocellular carcinoma. Post-operative outcome and long-term results in Europe: An overview Liver Transpl 10 2 Suppl. 1 2004 S58 S63
2. V. Mazzaferro, E. Regalia, and R. Doci Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis N Engl J Med 334 1996 693 699
3. B.Q. Cheng, C.Q. Jia, and C.T. Liu Chemoembolization combined with radiofrequency ablation for patients with hepatocellular carcinoma larger than 3 cm: A randomized controlled trial J Am Med Assoc 299 2008 1669 1677
4. T. Helmberger, S. Dogan, and G. Straub Liver resection or combined chemoembolization and radiofrequency ablation improve survival in patients with hepatocellular carcinoma Digestion 75 2007 104 112
5. J.M. Llovet, and J. Bruix Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival Hepatology 37 2003 429 442
6. T.J. Vogl, N.N. Naguib, and N.E. Nour-Eldin Review on transarterial chemoembolization in hepatocellular carcinoma: Palliative, combined, neoadjuvant, bridging, and symptomatic indications Eur J Radiol 72 2009 505 516
7. P.M. Lopez, A. Villanueva, and J.M. Llovet Systematic review: Evidence-based management of hepatocellular carcinoma - an updated analysis of randomized controlled trials Aliment Pharmacol Ther 23 2006 1535 1547
8. L.M. Sutherland, J.A. Williams, and R.T. Padbury Radiofrequency ablation of liver tumors: A systematic review Arch Surg 141 2006 181 190
9. J.M. Llovet, M. Sala, and J. Bruix Nonsurgical treatment of hepatocellular carcinoma Liver Transpl 6 6 Suppl. 2 2000 S11 S15
10. M.A. Hawkins, and L.A. Dawson Radiation therapy for hepatocellular carcinoma: From palliation to cure Cancer 106 2006 1653 1663
11. M. Mizumoto, K. Tokuuye, and S. Sugahara Proton beam therapy for hepatocellular carcinoma adjacent to the porta hepatis Int J Radiat Oncol Biol Phys 71 2008 462 467
12. M. Hata, K. Tokuuye, and S. Sugahara Proton beam therapy for aged patients with hepatocellular carcinoma Int J Radiat Oncol Biol Phys 69 2007 805 812
13. M. Hata, K. Tokuuye, and S. Sugahara Proton beam therapy for hepatocellular carcinoma patients with severe cirrhosis Strahlenther Onkol 182 2006 713 720 (Pubitemid 44887173)
14. M. Hata, K. Tokuuye, and S. Sugahara Proton beam therapy for hepatocellular carcinoma with limited treatment options Cancer 107 2006 591 598 (Pubitemid 44107220)
15. M. Hata, K. Tokuuye, and S. Sugahara Proton beam therapy for hepatocellular carcinoma with portal vein tumor thrombus Cancer 104 2005 794 801
16. T. Chiba, K. Tokuuye, and Y. Matsuzaki Proton beam therapy for hepatocellular carcinoma: A retrospective review of 162 patients Clin Cancer Res 11 2005 3799 3805 (Pubitemid 40685599)
17. N. Peters, G. Wieners, and M. Pech CT-guided interstitial brachytherapy of primary and secondary lung malignancies: Results of a prospective phase II trial Strahlenther Onkol 184 2008 296 301
18. G. Wieners, M. Pech, and M. Rudzinska CT-guided interstitial brachytherapy in the local treatment of extrahepatic, extrapulmonary secondary malignancies Eur Radiol 16 2006 2586 2593
19. J. Ricke, P. Wust, and G. Wieners CT-guided interstitial single-fraction brachytherapy of lung tumors: Phase I results of a novel technique Chest 127 2005 2237 2242
20. J. Ricke, P. Wust, and G. Wieners Liver malignancies: CT-guided interstitial brachytherapy in patients with unfavorable lesions for thermal ablation J Vasc Interv Radiol 15 2004 1279 1286 (Pubitemid 39487859)
21. J. Ricke, B. Hildebrandt, and A. Miersch Hepatic arterial port systems for treatment of liver metastases: Factors affecting patency and adverse events J Vasc Interv Radiol 15 2004 825 833
22. J. Ricke, P. Wust, and A. Stohlmann CT-guided interstitial brachytherapy of liver malignancies alone or in combination with thermal ablation: Phase I-II results of a novel technique Int J Radiat Oncol Biol Phys 58 2004 1496 1505
23. J. Bruix, M. Sherman, and J.M. Llovet Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver J Hepatol 35 2001 421 430
24. J. Ricke, P. Wust, and A. Stohlmann [CT-guided brachytherapy. A novel percutaneous technique for interstitial ablation of liver metastases] Strahlenther Onkol 180 2004 274 280 (Pubitemid 38667747)
25. J. Ricke, P. Wust, and A. Stohlmann CT-guided interstitial brachytherapy of liver malignancies alone or in combination with thermal ablation: Phase I-II results of a novel technique Int J Radiat Oncol Biol Phys 58 2004 1496 1505
26. J. Ricke, M. Seidensticker, and L. Ludemann In vivo assessment of the tolerance dose of small liver volumes after single-fraction HDR irradiation Int J Radiat Oncol Biol Phys 62 2005 776 784
27. P. Therasse, S.G. Arbuck, and E.A. Eisenhauer New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada J Natl Cancer Inst 92 2000 205 216
28. A. Grieco, M. Pompili, and G. Caminiti Prognostic factors for survival in patients with early-intermediate hepatocellular carcinoma undergoing non-surgical therapy: Comparison of Okuda, CLIP, and BCLC staging systems in a single Italian centre Gut 54 2005 411 418
29. J.M. Llovet, and J. Bruix Prospective validation of the Cancer of the Liver Italian Program (CLIP) score: A new prognostic system for patients with cirrhosis and hepatocellular carcinoma Hepatology 32 2000 679 680
30. J.M. Llovet, C. Bru, and J. Bruix Prognosis of hepatocellular carcinoma: The BCLC staging classification Semin Liver Dis 19 1999 329 338
31. K. Okuda, T. Ohtsuki, and H. Obata Natural history of hepatocellular carcinoma and prognosis in relation to treatment. Study of 850 patients Cancer 56 1985 918 928
32. S. Oquinena, M. Inarrairaegui, and Vila JJ Spontaneous regression of hepatocellular carcinoma: Three case reports and a categorized review of the literature Dig Dis Sci 54 2009 1147 1153
33. A.C. Randolph, E.M. Tharalson, and N. Gilani Spontaneous regression of hepatocellular carcinoma is possible and might have implications for future therapies Eur J Gastroenterol Hepatol 20 2008 804 809
34. V. Sibartie, J. Moriarty, and J. Crowe Spontaneous regression of hepatocellular carcinoma Am J Gastroenterol 103 2008 1050 1051
35. Y.K. Cho, J.K. Kim, and M.Y. Kim Systematic review of randomized trials for hepatocellular carcinoma treated with percutaneous ablation therapies Hepatology 49 2009 453 459
36. J.M. Llovet, S. Ricci, and V. Mazzaferro Sorafenib in advanced hepatocellular carcinoma N Engl J Med 359 2008 378 390
37. R.E. Schwarz, and D.D. Smith Trends in local therapy for hepatocellular carcinoma and survival outcomes in the US population Am J Surg 195 2008 829 836
38. E. Ben-Josef, D. Normolle, and W.D. Ensminger Phase II trial of high-dose conformal radiation therapy with concurrent hepatic artery floxuridine for unresectable intrahepatic malignancies J Clin Oncol 23 2005 8739 8747
39. U. Cillo, A. Vitale, and F. Grigoletto Prospective validation of the Barcelona Clinic Liver Cancer staging system J Hepatol 44 2006 723 731
40. Y.K. Cho, J.K. Kim, and M.Y. Kim Systematic review of randomized trials for hepatocellular carcinoma treated with percutaneous ablation therapies Hepatology 49 2009 453 459
41. L.A. Dawson The evolving role of radiation therapy in hepatocellular carcinoma Cancer Radiother 12 2008 96 101
42. J.P. Plastaras, S.H. Kim, and Y.Y. Liu Cell cycle dependent and schedule-dependent antitumor effects of sorafenib combined with radiation Cancer Res 67 2007 9443 9454
43. T.T. Cheung, K.K. Ng, R.T. Poon, and S.T. Fan Tolerance of radiofrequency ablation by patients of hepatocellular carcinoma J Hepatobiliary Pancreat Surg 16 2009 655 660
44. J.F. Buell, M.T. Thomas, and S. Rudich Experience with more than 500 minimally invasive hepatic procedures Ann Surg 248 2008 475 486
45. W.T. Kong, W.W. Zhang, and Y.D. Qiu Major complications after radiofrequency ablation for liver tumors: Analysis of 255 patients World J Gastroenterol 15 2009 2651 2656