Chemo-nociceptive signalling from the colon is enhanced by mild colitis and blocked by inhibition of transient receptor potential ankyrin 1 channels

British Journal of Pharmacology

Volumn 160, Issue 6, 2010, Pages 1430-1442

  Mitrovic, Martina ^a   Shahbazian, Anaid ^a   Bock, Elisabeth ^a   Pabst, Maria A ^a   Holzer, Peter ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

abdominal pain; allyl isothiocyanate; c Fos expression; capsaicin; chemical hyperresponsiveness; chemonociception; colitis; HC 030031; morphine; TRPA1; TRPV1

Indexed keywords

2 (1,3 DIMETHYL 2,6 DIOXO 1,2,3,6 TETRAHYDRO 7H PURIN 7 YL) N (4 ISOPROPYLPHENYL)ACETAMIDE; HC 030031; ISOTHIOCYANIC ACID; MORPHINE; MYELOPEROXIDASE; PROTEIN C FOS; PURINE DERIVATIVE; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; UNCLASSIFIED DRUG; 2-(1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL)-N-(4-ISOPROPYLPHENYL)ACETAMIDE; ACETANILIDE DERIVATIVE; ALLYL ISOTHIOCYANATE; CAPSAICIN; DEXTRAN SULFATE; ISOTHIOCYANIC ACID DERIVATIVE; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRPA1 PROTEIN, MOUSE;

ARTICLE; COLITIS; DISEASE ACTIVITY; DRUG EFFECT; DRUG MECHANISM; FEMALE; HISTOPATHOLOGY; HUMAN; MOUSE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPINAL CORD DORSAL HORN; ANIMAL; ANTAGONISTS AND INHIBITORS; COLON; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOPHYSIOLOGY; SENSORY NERVE CELL; TOXICITY;

ACETANILIDES; ANIMALS; CAPSAICIN; COLITIS; COLON; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; ISOTHIOCYANATES; MICE; MORPHINE; NEURONS, AFFERENT; PROTO-ONCOGENE PROTEINS C-FOS; PURINES; SIGNAL TRANSDUCTION; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

EID: 77954081324     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00794.x     Document Type: Article

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