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Volumn 115, Issue 2, 2010, Pages 369-378

Discovery of metabolic signatures for predicting whole organism toxicology

Author keywords

Ecotoxicogenomics; Genetic algorithm; Metabolism; Oxidative stress; Physiology; Predictive toxicology

Indexed keywords

COPPER; PENTACHLOROPHENOL;

EID: 77954073662     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq004     Document Type: Article
Times cited : (77)

References (40)
  • 1
    • 20444396620 scopus 로고    scopus 로고
    • The effect of environmental stress on absolute and mass-specific scope for growth in Daphnia magna Strauss
    • Baillieul, M., Smolders, R., and Blust, R. (2005). The effect of environmental stress on absolute and mass-specific scope for growth in Daphnia magna Strauss. Comp. Biochem. Physiol. C 140, 364-373.
    • (2005) Comp. Biochem. Physiol. C , vol.140 , pp. 364-373
    • Baillieul, M.1    Smolders, R.2    Blust, R.3
  • 3
    • 0025896706 scopus 로고
    • Induction of biotransformation in the liver of eel (Anguilla anguilla L) by sublethal exposure to dinitro-o-cresol: an ultrastructural and biochemical study
    • Braunbeck, T., and Volkl, A. (1991). Induction of biotransformation in the liver of eel (Anguilla anguilla L) by sublethal exposure to dinitro-o-cresol: an ultrastructural and biochemical study. Ecotoxicol. Environ. Saf. 21, 109-127.
    • (1991) Ecotoxicol. Environ. Saf. , vol.21 , pp. 109-127
    • Braunbeck, T.1    Volkl, A.2
  • 4
    • 38949209075 scopus 로고    scopus 로고
    • NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology
    • Coen, M., Holmes, E., Lindon, J. C., and Nicholson, J. K. (2008). NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology. Chem. Res. Toxicol. 21, 9-27.
    • (2008) Chem. Res. Toxicol. , vol.21 , pp. 9-27
    • Coen, M.1    Holmes, E.2    Lindon, J.C.3    Nicholson, J.K.4
  • 5
    • 0028973529 scopus 로고
    • Heavy metal and hydrocarbon pollution in recent sediments from Southampton Water Southern England: a geochemical and isotopic study
    • Croudace, I. W., and Cundy, A. B. (1995). Heavy metal and hydrocarbon pollution in recent sediments from Southampton Water, Southern England: a geochemical and isotopic study. Environ. Sci. Technol. 29, 1288-1296.
    • (1995) Environ. Sci. Technol. , vol.29 , pp. 1288-1296
    • Croudace, I.W.1    Cundy, A.B.2
  • 6
    • 0033559811 scopus 로고    scopus 로고
    • The contribution of anaerobic energy to gastropod crawling and a re-estimation of minimum cost of transport in the abalone Haliotis kamtschatkana (Jonas)
    • Donovan, D., Baldwin, J., and Carefoot, T. (1999). The contribution of anaerobic energy to gastropod crawling and a re-estimation of minimum cost of transport in the abalone, Haliotis kamtschatkana (Jonas). J. Exp. Mar. Biol. Ecol. 235, 273-284.
    • (1999) J. Exp. Mar. Biol. Ecol. , vol.235 , pp. 273-284
    • Donovan, D.1    Baldwin, J.2    Carefoot, T.3
  • 7
    • 36348960223 scopus 로고    scopus 로고
    • Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the Consortium on Metabonomic Toxicology screening approach
    • Ebbels, T. M. D., Keun, H. C., Beckonert, O. P., Bollard, M. E., Lindon, J. C., Holmes, E., and Nicholson, J. K. (2007). Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the Consortium on Metabonomic Toxicology screening approach. J. Proteome. Res. 6, 4407-4422.
    • (2007) J. Proteome. Res. , vol.6 , pp. 4407-4422
    • Ebbels, T.M.D.1    Keun, H.C.2    Beckonert, O.P.3    Bollard, M.E.4    Lindon, J.C.5    Holmes, E.6    Nicholson, J.K.7
  • 9
    • 29744451505 scopus 로고    scopus 로고
    • The use and misuse of biomarkers in ecotoxicology
    • Forbes, V. E., Palmqvist, A., and Bach, L. (2006). The use and misuse of biomarkers in ecotoxicology. Environ. Toxicol. Chem. 25, 272-280.
    • (2006) Environ. Toxicol. Chem. , vol.25 , pp. 272-280
    • Forbes, V.E.1    Palmqvist, A.2    Bach, L.3
  • 10
    • 0037735344 scopus 로고    scopus 로고
    • Copper toxicity, oxidative stress, and antioxidant nutrients
    • Gaetke, L. M., and Chow, C. K. (2003). Copper toxicity, oxidative stress, and antioxidant nutrients. Toxicology 189, 147-163.
    • (2003) Toxicology , vol.189 , pp. 147-163
    • Gaetke, L.M.1    Chow, C.K.2
  • 11
    • 0344673390 scopus 로고    scopus 로고
    • A deterministic ecological risk assessment for copper in European saltwater environments
    • Hall, L. W., and Anderson, R. D. (1999). A deterministic ecological risk assessment for copper in European saltwater environments. Mar. Pollut. Bull. 38, 207-218.
    • (1999) Mar. Pollut. Bull. , vol.38 , pp. 207-218
    • Hall, L.W.1    Anderson, R.D.2
  • 12
    • 34248165571 scopus 로고    scopus 로고
    • Direct sampling of organisms from the field and knowledge of their phenotype: key recommendations for environmental metabolomics
    • Hines, A., Oladiran, G., Bignell, J., Stentiford, G. D., and Viant, M. R. (2007a). Direct sampling of organisms from the field and knowledge of their phenotype: key recommendations for environmental metabolomics. Environ. Sci. Technol. 41, 3375-3381.
    • (2007) Environ. Sci. Technol. , vol.41 , pp. 3375-3381
    • Hines, A.1    Oladiran, G.2    Bignell, J.3    Stentiford, G.D.4    Viant, M.R.5
  • 13
    • 34548449421 scopus 로고    scopus 로고
    • Comparison of histological, genetic, metabolomic and lipid-based methods for sex determination in marine mussels
    • Hines, A., Yeung, W. H., Craft, J., Brown, M., Kennedy, J., Bignell, J., Stentiford, G. D., and Viant, M. R. (2007b). Comparison of histological, genetic, metabolomic and lipid-based methods for sex determination in marine mussels. Anal. Biochem. 369, 175-186.
    • (2007) Anal. Biochem. , vol.369 , pp. 175-186
    • Hines, A.1    Yeung, W.H.2    Craft, J.3    Brown, M.4    Kennedy, J.5    Bignell, J.6    Stentiford, G.D.7    Viant, M.R.8
  • 14
    • 28744447296 scopus 로고    scopus 로고
    • Acute and chronic effects of carrier solvents in aquatic organisms: a critical review
    • Hutchinson, T. H., Shillabeer, N., Winter, M. J., and Pickford, D. B. (2006). Acute and chronic effects of carrier solvents in aquatic organisms: a critical review. Aquat. Toxicol. 76, 69-92.
    • (2006) Aquat. Toxicol. , vol.76 , pp. 69-92
    • Hutchinson, T.H.1    Shillabeer, N.2    Winter, M.J.3    Pickford, D.B.4
  • 15
    • 56149109414 scopus 로고    scopus 로고
    • Metabolic profiling of Mytilus galloprovincialis and its potential applications for pollution assessment
    • Jones, O. A. H., Dondero, F., Viarengo, A., and Griffin, J. L. (2008). Metabolic profiling of Mytilus galloprovincialis and its potential applications for pollution assessment. Mar. Ecol. Prog. Ser. 369, 169-179.
    • (2008) Mar. Ecol. Prog. Ser. , vol.369 , pp. 169-179
    • Jones, O.A.H.1    Dondero, F.2    Viarengo, A.3    Griffin, J.L.4
  • 16
    • 0020331075 scopus 로고
    • Petroleum hydrocarbons in sediments of Southampton Water estuary
    • Knap, A. H., Williams, P. J. L., and Lysiak, E. (1982). Petroleum hydrocarbons in sediments of Southampton Water estuary. Mar. Environ. Res. 7, 235-249.
    • (1982) Mar. Environ. Res. , vol.7 , pp. 235-249
    • Knap, A.H.1    Williams, P.J.L.2    Lysiak, E.3
  • 17
    • 0036463681 scopus 로고    scopus 로고
    • Metabonomics: a platform for studying drug toxicity and gene function
    • Nicholson, J. K., Connelly, J., Lindon, J. C., and Holmes, E. (2002). Metabonomics: a platform for studying drug toxicity and gene function. Nat. Rev. Drug Discov. 1, 153-161.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 153-161
    • Nicholson, J.K.1    Connelly, J.2    Lindon, J.C.3    Holmes, E.4
  • 18
    • 0023815726 scopus 로고
    • The effect of copper, zinc and cadmium on the pumping rate of Mytilus edulis
    • Redpath, K. J., and Davenport, J. (1988). The effect of copper, zinc and cadmium on the pumping rate of Mytilus edulis. Aquat. Toxicol. 13, 217-226.
    • (1988) Aquat. Toxicol. , vol.13 , pp. 217-226
    • Redpath, K.J.1    Davenport, J.2
  • 19
    • 20544466649 scopus 로고    scopus 로고
    • Metabonomics in toxicology: a review
    • Robertson, D. G. (2005). Metabonomics in toxicology: a review. Toxicol. Sci. 85, 809-822.
    • (2005) Toxicol. Sci. , vol.85 , pp. 809-822
    • Robertson, D.G.1
  • 20
    • 34347229424 scopus 로고    scopus 로고
    • Dynamic range and mass accuracy of wide-scan direct infusion nanoelectrospray Fourier transform ion cyclotron resonance mass spectrometry-based metabolomics increased by the spectral stitching method
    • Southam, A. D., Payne, T. G., Cooper, H. J., Arvanitis, T. N., and Viant, M. R. (2007). Dynamic range and mass accuracy of wide-scan direct infusion nanoelectrospray Fourier transform ion cyclotron resonance mass spectrometry-based metabolomics increased by the spectral stitching method. Anal. Chem. 79, 4595-4602.
    • (2007) Anal. Chem. , vol.79 , pp. 4595-4602
    • Southam, A.D.1    Payne, T.G.2    Cooper, H.J.3    Arvanitis, T.N.4    Viant, M.R.5
  • 21
    • 0014828993 scopus 로고
    • Effects of trialkyltin and triphenyltin compounds on mitochondrial respiration
    • Stockdal, M., Dawson, A. P., and Selwyn, M. J. (1970). Effects of trialkyltin and triphenyltin compounds on mitochondrial respiration. Eur. J. Biochem. 15, 342-351.
    • (1970) Eur. J. Biochem. , vol.15 , pp. 342-351
    • Stockdal, M.1    Dawson, A.P.2    Selwyn, M.J.3
  • 22
    • 0345425705 scopus 로고    scopus 로고
    • Habitat as a factor involved in the physiological response to environmental anaerobiosis of white sea Mytilus edulis
    • Sukhotin, A. A., and Portner, H. O. (1999). Habitat as a factor involved in the physiological response to environmental anaerobiosis of white sea Mytilus edulis. Mar. Ecol. Prog. Ser. 184, 149-160.
    • (1999) Mar. Ecol. Prog. Ser. , vol.184 , pp. 149-160
    • Sukhotin, A.A.1    Portner, H.O.2
  • 24
    • 61849120270 scopus 로고    scopus 로고
    • A new approach to toxicity testing in Daphnia magna: application of high throughput FT-ICR mass spectrometry metabolomics
    • Taylor, N. S., Weber, R. J. M., Southam, A. D., Payne, T. G., Hrydziuszko, O., Arvanitis, T. N., and Viant, M. R. (2009). A new approach to toxicity testing in Daphnia magna: application of high throughput FT-ICR mass spectrometry metabolomics. Metabolomics 5, 44-58.
    • (2009) Metabolomics , vol.5 , pp. 44-58
    • Taylor, N.S.1    Weber, R.J.M.2    Southam, A.D.3    Payne, T.G.4    Hrydziuszko, O.5    Arvanitis, T.N.6    Viant, M.R.7
  • 25
    • 0025046339 scopus 로고
    • Uncouplers of oxidative phosphorylation
    • Terada, H. (1990). Uncouplers of oxidative phosphorylation. Environ. Health Perspect. 87, 213-218.
    • (1990) Environ. Health Perspect. , vol.87 , pp. 213-218
    • Terada, H.1
  • 26
    • 0034884086 scopus 로고    scopus 로고
    • Antifouling paint booster biocides in the UK coastal environment and potential risks of biological effects
    • Thomas, K. V., Fileman, T. W., Readman, J. W., and Waldock, M. J. (2001). Antifouling paint booster biocides in the UK coastal environment and potential risks of biological effects. Mar. Pollut. Bull. 42, 677-688.
    • (2001) Mar. Pollut. Bull. , vol.42 , pp. 677-688
    • Thomas, K.V.1    Fileman, T.W.2    Readman, J.W.3    Waldock, M.J.4
  • 27
    • 33646121277 scopus 로고    scopus 로고
    • GALGO: an R package for multivariate variable selection using genetic algorithms
    • Trevino, V., and Falciani, F. (2006). GALGO: an R package for multivariate variable selection using genetic algorithms. Bioinformatics 22, 1154-1156.
    • (2006) Bioinformatics , vol.22 , pp. 1154-1156
    • Trevino, V.1    Falciani, F.2
  • 28
    • 33751520251 scopus 로고    scopus 로고
    • Assessment of the impact of heavy metal pollution from a ferro-nickel smelting plant using biomarkers
    • Tsangaris, C., Papathanasiou, E., and Cotou, E. (2007). Assessment of the impact of heavy metal pollution from a ferro-nickel smelting plant using biomarkers. Ecotoxicol. Environ. Saf. 66, 232-243.
    • (2007) Ecotoxicol. Environ. Saf. , vol.66 , pp. 232-243
    • Tsangaris, C.1    Papathanasiou, E.2    Cotou, E.3
  • 31
    • 33646155341 scopus 로고    scopus 로고
    • Metabolic effects of dinoseb, diazinon and esfenvalerate in eyed eggs and alevins of Chinook salmon (Oncorhynchus tshawytscha) determined by H-1 NMR metabolomics
    • Viant, M. R., Pincetich, C. A., and Tjeerdema, R. S. (2006). Metabolic effects of dinoseb, diazinon and esfenvalerate in eyed eggs and alevins of Chinook salmon (Oncorhynchus tshawytscha) determined by H-1 NMR metabolomics. Aquat. Toxicol. 77, 359-371.
    • (2006) Aquat. Toxicol. , vol.77 , pp. 359-371
    • Viant, M.R.1    Pincetich, C.A.2    Tjeerdema, R.S.3
  • 32
    • 0001471774 scopus 로고
    • Heavy metals in marine invertebrates: mechanisms of regulation and toxicity at the cellular level
    • Viarengo, A. (1989). Heavy metals in marine invertebrates: mechanisms of regulation and toxicity at the cellular level. Rev. Aquat. Sci. 1, 295-317.
    • (1989) Rev. Aquat. Sci. , vol.1 , pp. 295-317
    • Viarengo, A.1
  • 34
    • 0030849329 scopus 로고    scopus 로고
    • Induction of glutathione depletion, p53 protein accumulation and cellular transformation by tetrachlorohydroquinone, a toxic metabolite of pentachlorophenol
    • Wang, Y. J., Ho, Y. S., Chu, S. W., Lien, H. J., Liu, T. H., and Lin, J. K. (1997). Induction of glutathione depletion, p53 protein accumulation and cellular transformation by tetrachlorohydroquinone, a toxic metabolite of pentachlorophenol. Chem.Biol. Interact. 105, 1-16.
    • (1997) Chem. Biol. Interact. , vol.105 , pp. 1-16
    • Wang, Y.J.1    Ho, Y.S.2    Chu, S.W.3    Lien, H.J.4    Liu, T.H.5    Lin, J.K.6
  • 35
    • 0025794116 scopus 로고
    • Role of physiological energetics in ecotoxicology
    • Widdows, J., and Donkin, P. (1991). Role of physiological energetics in ecotoxicology. Comp. Biochem. Physiol. C 100, 69-75.
    • (1991) Comp. Biochem. Physiol. C , vol.100 , pp. 69-75
    • Widdows, J.1    Donkin, P.2
  • 37
    • 0036567896 scopus 로고    scopus 로고
    • Measurement of stress effects (scope for growth) and contaminant levels in mussels (Mytilus edulis) collected from the Irish Sea
    • Widdows, J., Donkin, P., Staff, F. J., Matthiessen, P., Law, R. J., Allen, Y. T., Thain, J. E., Allchin, C. R., and Jones, B. R. (2002). Measurement of stress effects (scope for growth) and contaminant levels in mussels (Mytilus edulis) collected from the Irish Sea. Mar. Environ. Res. 53, 327-356.
    • (2002) Mar. Environ. Res. , vol.53 , pp. 327-356
    • Widdows, J.1    Donkin, P.2    Staff, F.J.3    Matthiessen, P.4    Law, R.J.5    Allen, Y.T.6    Thain, J.E.7    Allchin, C.R.8    Jones, B.R.9
  • 38
    • 49649094551 scopus 로고    scopus 로고
    • Biological effects of contaminants: measurement of scope for growth in mussels
    • Widdows, J., and Staff, F. J. (2006). Biological effects of contaminants: measurement of scope for growth in mussels. ICES Tech. Mar. Environ. Sci. 40, 1-30.
    • (2006) ICES Tech. Mar. Environ. Sci. , vol.40 , pp. 1-30
    • Widdows, J.1    Staff, F.J.2
  • 40
    • 36148989929 scopus 로고    scopus 로고
    • High-throughput tissue extraction protocol for NMR and MS-based metabolomics
    • Wu, H. F., Southam, A. D., Hines, A., and Viant, M. R. (2008). High-throughput tissue extraction protocol for NMR and MS-based metabolomics. Anal. Biochem. 372, 204-212.
    • (2008) Anal. Biochem. , vol.372 , pp. 204-212
    • Wu, H.F.1    Southam, A.D.2    Hines, A.3    Viant, M.R.4


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