Combining peripheral nerve grafting and matrix modulation to repair the injured rat spinal cord

Journal of Visualized Experiments

Volumn , Issue 33, 2010, Pages

  Houle, John D ^a   Amin, Arthi ^a   Cote, Marie Pascale ^a   Lemay, Michel ^a   Miller, Kassi ^a   Sandrow, Harra ^a   Santi, Lauren ^a   Shumsky, Jed ^a   Tom, Veronica ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77954041673     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/1324     Document Type: Article

References (4)

1. Houle, J.D. Demonstration of the potential for chronically injured neurons to regenerate axons into intraspinal peripheral nerve grafts. Exp. Neurol. 113, 1-9 (1991).
2. Ye, J.H. & Houle, J.D. Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons. Exp. Neurol. 143, 70-81 (1997).
3. Houle, J.D., Tom, V., Mayes, D., Wagoner, G., Phillips, N., & Silver, J. Combining an autologous peripheral nerve bridge and matrix modification by chondroitinase allows robust functional regeneration across a hemisection lesion of the adult rat spinal cord. J. Neurosci. 26, 7405-7415 (2006).
4. Tom, V. & Houle, J.D. Intraspinal microinjection of chondroitinase ABC following injury promotes axonal regeneration out of a peripheral nerve graft. Exp. Neurol. 211, 315-319 (2008).