Probiotics to prevent ventilator-associated pneumonia: No robust evidence from randomized controlled trials

Critical Care Medicine

Volumn 38, Issue 7, 2010, Pages 1616-1617

  Van Silvestri, Luciano ^a   Van Saene, Hendrick K ^b   Gregori, Dario ^c   Agostini, Susanna ^d   Francescon, Marisella ^e   Taylor, Nia ^b  

^a Presidio Ospedaliero   (Italy)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c UNIVERSITY OF PADOVA   (Italy)

^d Ospedale Civile di Gorizia   (Italy)

^e Basso Isontino District Health Service   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PROBIOTIC AGENT; SYNBIOTIC AGENT;

ARTIFICIAL VENTILATION; HUMAN; LETTER; OROPHARYNX; PRIORITY JOURNAL; RISK; VENTILATOR ASSOCIATED PNEUMONIA;

EID: 77954039827     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3181dd0a67     Document Type: Letter

References (5)

1. Siempos II, Ntaidou TK, Falagas ME: Impact of the administration of probiotics on the incidence of ventilator-associated pneumonia: A meta-analysis of randomized controlled trials. Crit Care Med 2010; 38: 954-962
2. Klarin B, Molin G, Jeppsson B, et al: Use of the probiotic Lactobacillus plantarum 299 to reduce pathogenic bacteria in the oropharynx of intubated patients: A randomised controlled open pilot study. Crit Care 2008; 12:R136
3. ®) in critically ill trauma patients: Early results of a randomized controlled trial. World J Surg 2006; 30: 1848-1855
4. Giamarellos-Bourboulis EJ, Bengmark S, Kannellakopoulou K, et al: Pro-and synbiotics to control inflammation and infection in patients with multiple injuries. J Trauma 2009; 67: 815-821
5. Morrow LE, Kollef MH, Bowers JB, et al: Pro-biotic manipulation of the native flora in critically ill patients: An opportunity for ventilator- associated pneumonia prophylaxis? Chest 2005; 128:144S