-
1
-
-
15744372810
-
KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
-
Pao W, Wang TY, Riely GJ et al. KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. PLoS Med 2005; 2(1): e17.
-
(2005)
PLoS Med
, vol.2
, Issue.1
-
-
Pao, W.1
Wang, T.Y.2
Riely, G.J.3
-
2
-
-
29244450494
-
High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor
-
Fujimoto N, Wislez M, Zhang J et al. High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor. Cancer Res 2005; 65(24): 11478-11485.
-
(2005)
Cancer Res
, vol.65
, Issue.24
, pp. 11478-11485
-
-
Fujimoto, N.1
Wislez, M.2
Zhang, J.3
-
3
-
-
33846994719
-
The impact of epidermal growth factor receptor gene status on gefitinib-treated Japanese patients with non-small-cell lung cancer
-
Ichihara S, Toyooka S, Fujiwara Y et al. The impact of epidermal growth factor receptor gene status on gefitinib-treated Japanese patients with non-small-cell lung cancer. Int J Cancer 2007; 120(6): 1239-1247.
-
(2007)
Int J Cancer
, vol.120
, Issue.6
, pp. 1239-1247
-
-
Ichihara, S.1
Toyooka, S.2
Fujiwara, Y.3
-
4
-
-
33646418681
-
Optimization of patient selection for gefitinib in non-small cell lung cancer by combined analysis of epidermal growth factor receptor mutation, K-ras mutation, and Akt phosphorylation
-
Han SW, Kim TY, Jeon YK et al. Optimization of patient selection for gefitinib in non-small cell lung cancer by combined analysis of epidermal growth factor receptor mutation, K-ras mutation, and Akt phosphorylation. Clin Cancer Res 2006; 12(8): 2538-2544.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.8
, pp. 2538-2544
-
-
Han, S.W.1
Kim, T.Y.2
Jeon, Y.K.3
-
5
-
-
34249810645
-
KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
-
Massarelli E, Varella-Garcia M, Tang X et al. KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer. Clin Cancer Res 2007; 13(10): 2890-2896.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.10
, pp. 2890-2896
-
-
Massarelli, E.1
Varella-Garcia, M.2
Tang, X.3
-
6
-
-
33846483745
-
EGFR and KRAS mutations as criteria for treatment with tyrosine kinase inhibitors: retro-and prospective observations in non-small-cell lung cancer
-
van Zandwijk N, Mathy A, Boerrigter L et al. EGFR and KRAS mutations as criteria for treatment with tyrosine kinase inhibitors: retro-and prospective observations in non-small-cell lung cancer. Ann Oncol 2007; 18(1): 99-103.
-
(2007)
Ann Oncol
, vol.18
, Issue.1
, pp. 99-103
-
-
van Zandwijk, N.1
Mathy, A.2
Boerrigter, L.3
-
7
-
-
61449341457
-
Epidermal growth factor receptor-related tumor markers and clinical outcomes with erlotinib in non-small cell lung cancer: an analysis of patients from German centers in the TRUST study
-
Schneider CP, Heigener D, Schott-von-Römer K et al. Epidermal growth factor receptor-related tumor markers and clinical outcomes with erlotinib in non-small cell lung cancer: an analysis of patients from German centers in the TRUST study. J Thorac Oncol 2008; 3(12): 1446-1453.
-
(2008)
J Thorac Oncol
, vol.3
, Issue.12
, pp. 1446-1453
-
-
Schneider, C.P.1
Heigener, D.2
Schott-von-Römer, K.3
-
8
-
-
67049088745
-
EGFR and HER2 genomic gain in recurrent non-small cell lung cancer after surgery: impact on outcome to treatment with gefitinib and association with EGFR and KRAS mutations in a Japanese cohort
-
Varella-Garcia M, Mitsudomi T, Yatabe Y et al. EGFR and HER2 genomic gain in recurrent non-small cell lung cancer after surgery: impact on outcome to treatment with gefitinib and association with EGFR and KRAS mutations in a Japanese cohort. J Thorac Oncol 2009; 4(3): 318-325.
-
(2009)
J Thorac Oncol
, vol.4
, Issue.3
, pp. 318-325
-
-
Varella-Garcia, M.1
Mitsudomi, T.2
Yatabe, Y.3
-
9
-
-
33750700477
-
Erlotinib for frontline treatment of advanced non-small cell lung cancer: a phase II study
-
Giaccone G, Gallegos Ruiz M, Le Chevalier T et al. Erlotinib for frontline treatment of advanced non-small cell lung cancer: a phase II study. Clin Cancer Res 2006; 12(20 Pt 1): 16049-16055.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.20 PT 1
, pp. 16049-16055
-
-
Giaccone, G.1
Gallegos Ruiz, M.2
Le Chevalier, T.3
-
10
-
-
33750962024
-
Molecular predictors of outcome with gefitinib in a phase III placebo-controlled study in advanced non-small-cell lung cancer
-
Hirsch FR, Varella-Garcia M, Bunn PA Jr et al. Molecular predictors of outcome with gefitinib in a phase III placebo-controlled study in advanced non-small-cell lung cancer. J Clin Oncol 2006; 24(31): 5034-5042.
-
(2006)
J Clin Oncol
, vol.24
, Issue.31
, pp. 5034-5042
-
-
Hirsch, F.R.1
Varella-Garcia, M.2
Bunn P.A., Jr.3
-
11
-
-
34047132314
-
Combination of EGFR gene copy number and protein expression predicts outcome for advanced non-small-cell lung cancer patients treated with gefitinib
-
Hirsch FR, Varella-Garcia M, Cappuzzo F et al. Combination of EGFR gene copy number and protein expression predicts outcome for advanced non-small-cell lung cancer patients treated with gefitinib. Ann Oncol 2007; 18(4): 752-760.
-
(2007)
Ann Oncol
, vol.18
, Issue.4
, pp. 752-760
-
-
Hirsch, F.R.1
Varella-Garcia, M.2
Cappuzzo, F.3
-
12
-
-
33947504732
-
Phase II clinical trial of chemotherapynaive patients > or = 70 years of age treated with erlotinib for advanced nonsmall-cell lung cancer
-
Jackman DM, Yeap BY, Lindeman NI et al. Phase II clinical trial of chemotherapynaive patients > or = 70 years of age treated with erlotinib for advanced nonsmall-cell lung cancer. J Clin Oncol 2007; 25(7): 760-766.
-
(2007)
J Clin Oncol
, vol.25
, Issue.7
, pp. 760-766
-
-
Jackman, D.M.1
Yeap, B.Y.2
Lindeman, N.I.3
-
13
-
-
52049090365
-
Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21
-
Zhu CQ, da Cunha Santos G, Ding K et al. Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21. J Clin Oncol 2008; 26(26): 4268-4275.
-
(2008)
J Clin Oncol
, vol.26
, Issue.26
, pp. 4268-4275
-
-
Zhu, C.Q.1
da Cunha Santos, G.2
Ding, K.3
-
14
-
-
41149097557
-
Molecular characteristics of bronchioloalveolar carcinoma and adenocarcinoma, bronchioloalveolar carcinoma subtype, predict response to erlotinib
-
Miller VA, Riely GJ, Zakowski MF et al. Molecular characteristics of bronchioloalveolar carcinoma and adenocarcinoma, bronchioloalveolar carcinoma subtype, predict response to erlotinib. J Clin Oncol 2008; 26(9): 1472-1478.
-
(2008)
J Clin Oncol
, vol.26
, Issue.9
, pp. 1472-1478
-
-
Miller, V.A.1
Riely, G.J.2
Zakowski, M.F.3
-
15
-
-
52449101985
-
A phase II pharmacodynamic study of erlotinib in patients with advanced non-small cell lung cancer previously treated with platinum-based chemotherapy
-
Felip E, Rojo F, Reck M et al. A phase II pharmacodynamic study of erlotinib in patients with advanced non-small cell lung cancer previously treated with platinum-based chemotherapy. Clin Cancer Res 2008; 14(12): 3867-3874.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.12
, pp. 3867-3874
-
-
Felip, E.1
Rojo, F.2
Reck, M.3
-
16
-
-
41549125361
-
Multicenter phase II trial of gefitinib firstline therapy followed by chemotherapy in advanced non-small-cell lung cancer (NSCLC): SAKK protocol 19/03
-
D'Addario G, Rauch D, Stupp R et al. Multicenter phase II trial of gefitinib firstline therapy followed by chemotherapy in advanced non-small-cell lung cancer (NSCLC): SAKK protocol 19/03. Ann Oncol 2008; 19(4): 739-745.
-
(2008)
Ann Oncol
, vol.19
, Issue.4
, pp. 739-745
-
-
D'Addario, G.1
Rauch, D.2
Stupp, R.3
-
17
-
-
52749099497
-
Assessmentofsomatick-RASmutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
-
Linardou H, Dahabreh IJ, Kanaloupiti D et al. Assessmentofsomatick-RASmutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer. Lancet Oncol 2008; 9(10): 962-972.
-
(2008)
Lancet Oncol
, vol.9
, Issue.10
, pp. 962-972
-
-
Linardou, H.1
DahabrehIJ, KanaloupitiD.2
-
18
-
-
77953995551
-
Clinical outcomes with erlotinib in relation to biomarker status: analyses from the open label TRUST study in advanced nonsmall cell lung cancer
-
Pirker R, Su W, Rooneem R et al. Clinical outcomes with erlotinib in relation to biomarker status: analyses from the open label TRUST study in advanced nonsmall cell lung cancer. Ann Oncol 2008; 19 (Suppl 8): viii100.
-
(2008)
Ann Oncol
, vol.19
, Issue.SUPPL 8
-
-
Pirker, R.1
Su, W.2
Rooneem, R.3
-
19
-
-
69349088824
-
Impact of epidermal growth factor receptor and KRAS mutations on clinical outcomes in previously untreated nonsmall cell lung cancer patients: results of an online tumor registry of clinical trials
-
Jackman DM, Miller VA, Cioffredi LA et al. Impact of epidermal growth factor receptor and KRAS mutations on clinical outcomes in previously untreated nonsmall cell lung cancer patients: results of an online tumor registry of clinical trials. Clin Cancer Res 2009; 15: 5267-5273.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5267-5273
-
-
Jackman, D.M.1
Miller, V.A.2
Cioffredi, L.A.3
-
20
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
Shepherd FA, Rodrigues Pereira J, Ciuleanu T et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005; 353(2): 123-132.
-
(2005)
N Engl J Med
, vol.353
, Issue.2
, pp. 123-132
-
-
Shepherd, F.A.1
Rodrigues Pereira, J.2
Ciuleanu, T.3
-
21
-
-
77949885180
-
Favorable response to erlotinib in a lung adenocarcinoma with both epidermal growth factor receptor exon 19 deletion and K-ras G13D mutations
-
Lee CN, Chen HY, Liu HE. Favorable response to erlotinib in a lung adenocarcinoma with both epidermal growth factor receptor exon 19 deletion and K-ras G13D mutations. J Clin Oncol 2010; 28(7): e111-112.
-
(2010)
J Clin Oncol
, vol.28
, Issue.7
-
-
Lee, C.N.1
Chen, H.Y.2
Liu, H.E.3
-
22
-
-
65649108558
-
A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival
-
Singh A, Greninger P, Rhodes D et al. A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival. Cancer Cell. 2009; 15(6): 489-500.
-
(2009)
Cancer Cell
, vol.15
, Issue.6
, pp. 489-500
-
-
Singh, A.1
Greninger, P.2
Rhodes, D.3
|