-
1
-
-
38049115129
-
Endogenous human microRNAs that suppress breast cancer metastasis
-
Tavazoie SF, Alarcon C, Oskarsson T, Padua D, Wang Q, Bos PD, et al. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 2008; 451:147-52.
-
(2008)
Nature
, vol.451
, pp. 147-152
-
-
Tavazoie, S.F.1
Alarcon, C.2
Oskarsson, T.3
Padua, D.4
Wang, Q.5
Bos, P.D.6
-
2
-
-
33645124258
-
Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs
-
Giraldez AJ, Mishima Y, Rihel J, Grocock RJ, Van Dongen S, Inoue K, et al. Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science 2006; 312:75-9.
-
(2006)
Science
, vol.312
, pp. 75-79
-
-
Giraldez, A.J.1
Mishima, Y.2
Rihel, J.3
Grocock, R.J.4
Van Dongen, S.5
Inoue, K.6
-
3
-
-
35348914716
-
Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430
-
Choi WY, Giraldez AJ, Schier AF. Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430. Science 2007; 318:271-4.
-
(2007)
Science
, vol.318
, pp. 271-274
-
-
Choi, W.Y.1
Giraldez, A.J.2
Schier, A.F.3
-
4
-
-
76349122201
-
Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
-
In press
-
Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, et al. Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans. Nat Struct Mol Biol 2010; In press.
-
(2010)
Nat Struct Mol Biol
-
-
Zisoulis, D.G.1
Lovci, M.T.2
Wilbert, M.L.3
Hutt, K.R.4
Liang, T.Y.5
Pasquinelli, A.E.6
-
5
-
-
36749036712
-
Functional screening identifies miR-315 as a potent activator of Wingless signaling
-
Silver SJ, Hagen JW, Okamura K, Perrimon N, Lai EC. Functional screening identifies miR-315 as a potent activator of Wingless signaling. Proc Natl Acad Sci USA 2007; 104:18151-6.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 18151-18156
-
-
Silver, S.J.1
Hagen, J.W.2
Okamura, K.3
Perrimon, N.4
Lai, E.C.5
-
6
-
-
71149108895
-
Conserved MicroRNA miR-8/miR-200 and its target USH/FOG2 control growth by regulating PI3K
-
Hyun S, Lee JH, Jin H, Nam J, Namkoong B, Lee G, et al. Conserved MicroRNA miR-8/miR-200 and its target USH/FOG2 control growth by regulating PI3K. Cell 2009; 139:1096-108.
-
(2009)
Cell
, vol.139
, pp. 1096-1108
-
-
Hyun, S.1
Lee, J.H.2
Jin, H.3
Nam, J.4
Namkoong, B.5
Lee, G.6
-
7
-
-
59849122726
-
MicroRNA-221-222 regulate the cell cycle in mast cells
-
Mayoral RJ, Pipkin ME, Pachkov M, van Nimwegen E, Rao A, Monticelli S. MicroRNA-221-222 regulate the cell cycle in mast cells. J Immunol 2009; 182:433-45.
-
(2009)
J Immunol
, vol.182
, pp. 433-445
-
-
Mayoral, R.J.1
Pipkin, M.E.2
Pachkov, M.3
van Nimwegen, E.4
Rao, A.5
Monticelli, S.6
-
8
-
-
67149115119
-
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
-
Khan AA, Betel D, Miller ML, Sander C, Leslie CS, Marks DS. Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs. Nat Biotechnol 2009; 27:549-55.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 549-555
-
-
Khan, A.A.1
Betel, D.2
Miller, M.L.3
Sander, C.4
Leslie, C.S.5
Marks, D.S.6
-
9
-
-
72449129174
-
A global view of genomic information-moving beyond the gene and the master regulator
-
Mattick JS, Taft RJ, Faulkner GJ. A global view of genomic information-moving beyond the gene and the master regulator. Trends Genet 2009; 26:21-8.
-
(2009)
Trends Genet
, vol.26
, pp. 21-28
-
-
Mattick, J.S.1
Taft, R.J.2
Faulkner, G.J.3
-
10
-
-
34548230885
-
Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas
-
Calin GA, Liu CG, Ferracin M, Hyslop T, Spizzo R, Sevignani C, et al. Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas. Cancer Cell 2007; 12:215-29.
-
(2007)
Cancer Cell
, vol.12
, pp. 215-229
-
-
Calin, G.A.1
Liu, C.G.2
Ferracin, M.3
Hyslop, T.4
Spizzo, R.5
Sevignani, C.6
-
11
-
-
77649221027
-
Non-codingRNA Sequence Variations in Human Chronic Lymphocytic Leukemia and Colorectal Cancer
-
Wojcik SE, Rossi S, Shimizu M, Nicoloso M, Cimmino A, Alder H, et al. Non-codingRNA Sequence Variations in Human Chronic Lymphocytic Leukemia and Colorectal Cancer. Carcinogenesis 2009; 31:208-15.
-
(2009)
Carcinogenesis
, vol.31
, pp. 208-215
-
-
Wojcik, S.E.1
Rossi, S.2
Shimizu, M.3
Nicoloso, M.4
Cimmino, A.5
Alder, H.6
-
12
-
-
59649125888
-
Biological basis for restriction of microRNA targets to the 3' untranslated region in mammalian mRNAs
-
Gu S, Jin L, Zhang F, Sarnow P, Kay MA. Biological basis for restriction of microRNA targets to the 3' untranslated region in mammalian mRNAs. Nat Struct Mol Biol 2009; 16:144-50.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 144-150
-
-
Gu, S.1
Jin, L.2
Zhang, F.3
Sarnow, P.4
Kay, M.A.5
-
13
-
-
72749089855
-
A novel class of small RNAs: TRNA-derived RNA fragments (tRFs)
-
Lee YS, Shibata Y, Malhotra A, Dutta A. A novel class of small RNAs: tRNA-derived RNA fragments (tRFs). Genes Dev 2009; 23:2639-49.
-
(2009)
Genes Dev
, vol.23
, pp. 2639-2649
-
-
Lee, Y.S.1
Shibata, Y.2
Malhotra, A.3
Dutta, A.4
-
14
-
-
69949171557
-
p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence
-
Fujita K, Mondal AM, Horikawa I, Nguyen GH, Kumamoto K, Sohn JJ, et al. p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence. Nat Cell Biol 2009; 11:1135-42.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1135-1142
-
-
Fujita, K.1
Mondal, A.M.2
Horikawa, I.3
Nguyen, G.H.4
Kumamoto, K.5
Sohn, J.J.6
-
15
-
-
67649979858
-
The mir-34 microRNA is required for the DNA damage response in vivo in C. elegans and in vitro in human breast cancer cells
-
Kato M, Paranjape T, Muller RU, Nallur S, Gillespie E, Keane K, et al. The mir-34 microRNA is required for the DNA damage response in vivo in C. elegans and in vitro in human breast cancer cells. Oncogene 2009; 28:2419-24.
-
(2009)
Oncogene
, vol.28
, pp. 2419-2424
-
-
Kato, M.1
Paranjape, T.2
Muller, R.U.3
Nallur, S.4
Gillespie, E.5
Keane, K.6
-
16
-
-
74049097902
-
Chronic lymphocytic leukemia: Interplay between noncoding RNAs and protein-coding genes
-
Calin GA, Croce CM. Chronic lymphocytic leukemia: interplay between noncoding RNAs and protein-coding genes. Blood 2009; 114:4761-70.
-
(2009)
Blood
, vol.114
, pp. 4761-4770
-
-
Calin, G.A.1
Croce, C.M.2
-
17
-
-
25444520537
-
miR-15 and miR-16 induce apoptosis by targeting BCL2
-
Cimmino A, Calin GA, Fabbri M, Iorio MV, Ferracin M, Shimizu M, et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 2005; 102:13944-9.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13944-13949
-
-
Cimmino, A.1
Calin, G.A.2
Fabbri, M.3
Iorio, M.V.4
Ferracin, M.5
Shimizu, M.6
-
18
-
-
35649020283
-
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
-
Fabbri M, Garzon R, Cimmino A, Liu Z, Zanesi N, Callegari E, et al. MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci USA 2007; 104:15805-10.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15805-15810
-
-
Fabbri, M.1
Garzon, R.2
Cimmino, A.3
Liu, Z.4
Zanesi, N.5
Callegari, E.6
-
19
-
-
33646056975
-
A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors
-
Voorhoeve PM, le Sage C, Schrier M, Gillis AJ, Stoop H, Nagel R, et al. A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell 2006; 124:1169-81.
-
(2006)
Cell
, vol.124
, pp. 1169-1181
-
-
Voorhoeve, P.M.1
le Sage, C.2
Schrier, M.3
Gillis, A.J.4
Stoop, H.5
Nagel, R.6
-
20
-
-
55549129277
-
In-depth characterization of the microRNA transcriptome in a leukemia progression model
-
Kuchenbauer F, Morin RD, Argiropoulos B, Petriv OI, Griffith M, Heuser M, et al. In-depth characterization of the microRNA transcriptome in a leukemia progression model. Genome Res 2008; 18:1787-97.
-
(2008)
Genome Res
, vol.18
, pp. 1787-1797
-
-
Kuchenbauer, F.1
Morin, R.D.2
Argiropoulos, B.3
Petriv, O.I.4
Griffith, M.5
Heuser, M.6
-
21
-
-
70449807097
-
MicroRNAs regulate human embryonic stem cell division
-
Qi J, Yu JY, Shcherbata HR, Mathieu J, Wang AJ, Seal S, et al. microRNAs regulate human embryonic stem cell division. Cell Cycle 2009; 8:3729-41.
-
(2009)
Cell Cycle
, vol.8
, pp. 3729-3741
-
-
Qi, J.1
Yu, J.Y.2
Shcherbata, H.R.3
Mathieu, J.4
Wang, A.J.5
Seal, S.6
-
22
-
-
33748587841
-
A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes
-
Miranda KC, Huynh T, Tay Y, Ang YS, Tam WL, Thomson AM, et al. A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes. Cell 2006; 126:1203-17.
-
(2006)
Cell
, vol.126
, pp. 1203-1217
-
-
Miranda, K.C.1
Huynh, T.2
Tay, Y.3
Ang, Y.S.4
Tam, W.L.5
Thomson, A.M.6
-
23
-
-
65949121645
-
New tricks for animal microRNAS: Targeting of amino acid coding regions at conserved and nonconserved sites
-
Rigoutsos I. New tricks for animal microRNAS: targeting of amino acid coding regions at conserved and nonconserved sites. Cancer Res 2009; 69:3245-8.
-
(2009)
Cancer Res
, vol.69
, pp. 3245-3248
-
-
Rigoutsos, I.1
-
24
-
-
70349577785
-
Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling
-
Paroo Z, Ye X, Chen S, Liu Q. Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling. Cell 2009; 139:112-22.
-
(2009)
Cell
, vol.139
, pp. 112-122
-
-
Paroo, Z.1
Ye, X.2
Chen, S.3
Liu, Q.4
-
25
-
-
34948901976
-
Structural determinants of RNA recognition and cleavage by Dicer
-
MacRae IJ, Zhou K, Doudna JA. Structural determinants of RNA recognition and cleavage by Dicer. Nat Struct Mol Biol 2007; 14:934-40.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 934-940
-
-
MacRae, I.J.1
Zhou, K.2
Doudna, J.A.3
-
26
-
-
70350783745
-
Structural insights into RNA processing by the human RISC-loading complex
-
Wang HW, Noland C, Siridechadilok B, Taylor DW, Ma E, Felderer K, et al. Structural insights into RNA processing by the human RISC-loading complex. Nat Struct Mol Biol 2009; 16:1148-53.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 1148-1153
-
-
Wang, H.W.1
Noland, C.2
Siridechadilok, B.3
Taylor, D.W.4
Ma, E.5
Felderer, K.6
et al7
-
27
-
-
75649133887
-
Expanded RNA-binding activities of mammalian Argonaute 2
-
Tan GS, Garchow BG, Liu X, Yeung J, Morris JPt, Cuellar TL, et al. Expanded RNA-binding activities of mammalian Argonaute 2. Nucleic Acids Res 2009; 37:7533-45.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 7533-7545
-
-
Tan, G.S.1
Garchow, B.G.2
Liu, X.3
Yeung, J.4
Morris, J.P.T.5
Cuellar, T.L.6
-
28
-
-
58149511979
-
RNA interference and retinoblastoma-related genes are required for repression of endogenous siRNA targets in Caenorhabditis elegans
-
Grishok A, Hoersch S, Sharp PA. RNA interference and retinoblastoma-related genes are required for repression of endogenous siRNA targets in Caenorhabditis elegans. Proc Natl Acad Sci USA 2008; 105:20386-91.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20386-20391
-
-
Grishok, A.1
Hoersch, S.2
Sharp, P.A.3
-
29
-
-
28444433734
-
Negative regulation of nuclear divisions in Caenorhabditis elegans by retinoblastoma and RNA interference-related genes
-
Grishok A, Sharp PA. Negative regulation of nuclear divisions in Caenorhabditis elegans by retinoblastoma and RNA interference-related genes. Proc Natl Acad Sci USA 2005; 102:17360-5.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17360-17365
-
-
Grishok, A.1
Sharp, P.A.2
-
30
-
-
40749111551
-
A skin microRNA promotes differentiation by repressing 'stemness'
-
Yi R, Poy MN, Stoffel M, Fuchs E. A skin microRNA promotes differentiation by repressing 'stemness'. Nature 2008; 452:225-9.
-
(2008)
Nature
, vol.452
, pp. 225-229
-
-
Yi, R.1
Poy, M.N.2
Stoffel, M.3
Fuchs, E.4
-
31
-
-
70350038073
-
Systematic analysis of dynamic miRNA-target interactions during C. elegans development
-
Zhang L, Hammell M, Kudlow BA, Ambros V, Han M. Systematic analysis of dynamic miRNA-target interactions during C. elegans development. Development 2009; 136:3043-55.
-
(2009)
Development
, vol.136
, pp. 3043-3055
-
-
Zhang, L.1
Hammell, M.2
Kudlow, B.A.3
Ambros, V.4
Han, M.5
-
32
-
-
42049103216
-
The let-7 microRNA reduces tumor growth in mouse models of lung cancer
-
Esquela-Kerscher A, Trang P, Wiggins JF, Patrawala L, Cheng A, Ford L, et al. The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle 2008; 7:759-64.
-
(2008)
Cell Cycle
, vol.7
, pp. 759-764
-
-
Esquela-Kerscher, A.1
Trang, P.2
Wiggins, J.F.3
Patrawala, L.4
Cheng, A.5
Ford, L.6
-
33
-
-
37249092180
-
A viral microRNA functions as an orthologue of cellular miR-155
-
Gottwein E, Mukherjee N, Sachse C, Frenzel C, Majoros WH, Chi JT, et al. A viral microRNA functions as an orthologue of cellular miR-155. Nature 2007; 450:1096-9.
-
(2007)
Nature
, vol.450
, pp. 1096-1099
-
-
Gottwein, E.1
Mukherjee, N.2
Sachse, C.3
Frenzel, C.4
Majoros, W.H.5
Chi, J.T.6
-
34
-
-
69949098536
-
miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell cycle genes via binding to "seedless" 3'UTR microRNA recognition elements
-
Lal A, Navarro F, Maher CA, Maliszewski LE, Yan N, O'Day E, et al. miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell cycle genes via binding to "seedless" 3'UTR microRNA recognition elements. Mol Cell 2009; 35:610-25.
-
(2009)
Mol Cell
, vol.35
, pp. 610-625
-
-
Lal, A.1
Navarro, F.2
Maher, C.A.3
Maliszewski, L.E.4
Yan, N.5
O'Day, E.6
-
35
-
-
46249092601
-
Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites
-
Sandberg R, Neilson JR, Sarma A, Sharp PA, Burge CB. Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites. Science 2008; 320:1643-7.
-
(2008)
Science
, vol.320
, pp. 1643-1647
-
-
Sandberg, R.1
Neilson, J.R.2
Sarma, A.3
Sharp, P.A.4
Burge, C.B.5
-
36
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y, et al. A microRNA component of the p53 tumour suppressor network. Nature 2007; 447:1130-4.
-
(2007)
Nature
, vol.447
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.P.3
de Stanchina, E.4
Xuan, Z.5
Liang, Y.6
-
37
-
-
72849120988
-
miR-19 is a key oncogenic component of mir-17-92
-
Olive V, Bennett MJ, Walker JC, Ma C, Jiang I, Cordon-Cardo C, et al. miR-19 is a key oncogenic component of mir-17-92. Genes Dev 2009; 23:2839-49.
-
(2009)
Genes Dev
, vol.23
, pp. 2839-2849
-
-
Olive, V.1
Bennett, M.J.2
Walker, J.C.3
Ma, C.4
Jiang, I.5
Cordon-Cardo, C.6
-
38
-
-
54249117763
-
A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk
-
Chin LJ, Ratner E, Leng S, Zhai R, Nallur S, Babar I, et al. A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. Cancer Res 2008; 68:8535-40.
-
(2008)
Cancer Res
, vol.68
, pp. 8535-8540
-
-
Chin, L.J.1
Ratner, E.2
Leng, S.3
Zhai, R.4
Nallur, S.5
Babar, I.6
-
39
-
-
47949100595
-
Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
-
Newman MA, Thomson JM, Hammond SM. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. Rna 2008; 14:1539-49.
-
(2008)
Rna
, vol.14
, pp. 1539-1549
-
-
Newman, M.A.1
Thomson, J.M.2
Hammond, S.M.3
-
41
-
-
61349127117
-
A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function
-
Melo SA, Ropero S, Moutinho C, Aaltonen LA, Yamamoto H, Calin GA, et al. A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. Nat Genet 2009; 41:365-70.
-
(2009)
Nat Genet
, vol.41
, pp. 365-370
-
-
Melo, S.A.1
Ropero, S.2
Moutinho, C.3
Aaltonen, L.A.4
Yamamoto, H.5
Calin, G.A.6
-
42
-
-
57749183871
-
Regulating the regulators: Mechanisms controlling the maturation of microRNAs
-
Ding XC, Weiler J, Grosshans H. Regulating the regulators: mechanisms controlling the maturation of microRNAs. Trends Biotechnol 2009; 27:27-36.
-
(2009)
Trends Biotechnol
, vol.27
, pp. 27-36
-
-
Ding, X.C.1
Weiler, J.2
Grosshans, H.3
-
43
-
-
70349453924
-
Active turnover modulates mature microRNA activity in Caenorhabditis elegans
-
Chatterjee S, Grosshans H. Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature 2009; 461:546-9.
-
(2009)
Nature
, vol.461
, pp. 546-549
-
-
Chatterjee, S.1
Grosshans, H.2
-
44
-
-
70349810911
-
LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans
-
Lehrbach NJ, Armisen J, Lightfoot HL, Murfitt KJ, Bugaut A, Balasubramanian S, et al. LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans. Nat Struct Mol Biol 2009; 16:1016-20.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 1016-1020
-
-
Lehrbach, N.J.1
Armisen, J.2
Lightfoot, H.L.3
Murfitt, K.J.4
Bugaut, A.5
Balasubramanian, S.6
|