Bioisosteric replacement of molecular scaffolds: From natural products to synthetic compounds

Natural Product Communications

Volumn 3, Issue 8, 2008, Pages 1355-1360

  Grabowski, Kristina ^a   Proschak, Ewgenij ^a   Baringhaus, Karl Heinz ^b   Rau, Oliver ^a   Schubert Zsilavecz, Manfred ^a   Schneider, Gisbert ^a  

^a GOETHE UNIVERSITY   (Germany)

^b SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

Author keywords

Beta turn mimetic; Bioisoster; Compactin; PPAR; Re scaffolding; Statin; Virtual screening

Indexed keywords

MOLECULAR SCAFFOLD; NATURAL PRODUCT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST;

ARTICLE; BETA TURN; BIOMIMETICS; DRUG ACTIVITY; MOLECULAR LIBRARY; PROSPECTIVE STUDY; SCREENING; VALIDATION PROCESS;

EID: 77953973777     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: 10.1177/1934578x0800300821     Document Type: Article

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