Localization of osteoblast inflammatory cytokines MCP-1 and VEGF to the matrix of the trabecula of the femur, a target area for metastatic breast cancer cell colonization

Clinical and Experimental Metastasis

Volumn 27, Issue 5, 2010, Pages 331-340

  Bussard, Karen M ^a   Okita, Noriaki ^a,b   Sharkey, Neil ^a   Neuberger, Thomas ^a   Webb, Andrew ^a   Mastro, Andrea M ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b The Pennsylvania State University   (United States)

Author keywords

Bone; Breast cancer; IL 6; MCP 1; Metastasis; VEGF

Indexed keywords

INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; VASCULOTROPIN; CCL2 PROTEIN, HUMAN; VASCULOTROPIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW; BONE MATRIX; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CANCER LOCALIZATION; CELLULAR DISTRIBUTION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FEMALE; FEMUR; HEART LEFT VENTRICLE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; METAPHYSIS; METASTASIS; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OSTEOBLAST; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TRABECULAR BONE; ANIMAL; BONE TUMOR; BREAST TUMOR; CANCER TRANSPLANTATION; METABOLISM; NUDE MOUSE; PATHOLOGY;

ANIMALS; BONE NEOPLASMS; BREAST NEOPLASMS; CHEMOKINE CCL2; FEMALE; FEMUR; IMMUNOHISTOCHEMISTRY; MAGNETIC RESONANCE IMAGING; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77953953240     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-010-9330-3     Document Type: Article

References (45)

1. Society AC (2007) Cancer Statistics, 2007. American Cancer Society, Atlanta
2. TA Guise WM Kozlow A Heras-Herzig SS Padalecki JJ Yin JM Chirgwin 2005 Molecular mechanisms of breast cancer metastases to bone Clin Breast Cancer 5 Suppl S46 S53 10.3816/CBC.2005.s.004 1:CAS:528:DC%2BD2MXktFyhsrw%3D 15807924
3. Marks SC, Odgren PR (2002) Structure and development of the skeleton. In: Bilezikian JP, Raisz LG, Rodan GA (eds) Principles of bone biology. Academic Press, New York, pp 3-15
4. EF Solomayer IJ Diel GC Meyberg, et al. 2000 Metastatic breast cancer: clinical course, prognosis and therapy related to the first site of metastasis Breast Cancer Res Treat 59 3 271 278 10.1023/A:1006308619659 1:STN:280:DC%2BD3cvjt12qtg%3D%3D 10832597 (Pubitemid 30243049)
5. PA Phadke RR Mercer JF Harms, et al. 2006 Kinetics of metastatic breast cancer cell trafficking in bone Clin Cancer Res 12 1431 1440 10.1158/1078-0432.CCR-05-1806 16533765
6. TA Guise 2000 Molecular mechanisms of osteolytic bone metastases Cancer 88 2892 2898 10.1002/1097-0142(20000615)88:12+<2892::AID-CNCR2>3.0.CO;2-Y 1:CAS:528:DC%2BD3cXksVCms7k%3D 10898330
7. Canalis E (2003) Osteogenic growth factors. In: Flavus MJ (ed) Primer on the metabolic bone diseases and disorders of mineral metabolism, 5th edition. American Society for Bone and Mineral Research, Washington, DC, pp 28-31
8. W Kozlow TA Guise 2005 Breast cancer metastasis to bone: mechanisms of osteolysis and implications for therapy J Mammary Gland Biol Neoplasia 10 2 169 180 10.1007/s10911-005-5399-8 16025223 (Pubitemid 41031006)
9. Mundy GR, Chen D, Oyajobi BO (2003) Bone remodeling. In: Favus MJ (ed) Primer on the metabolic bone diseases and disorders of mineral metabolism. American Society for Bone and Mineral Research, Washington, DC, pp 46-57
10. GR Mundy 2002 Metastasis to bone: causes, consequences and therapeutic opportunities Nat Rev Cancer 2 584 593 10.1038/nrc867 1:CAS:528: DC%2BD38XlslGqsLo%3D 12154351 (Pubitemid 37328925)
11. T Hiraga PJ Williams GR Mundy 2001 The bisphosphonate ibandronate promotes apoptosis in MDA-MB-231 human breast cancer cells in bone metastases Cancer Res 61 4418 4424 1:CAS:528:DC%2BD3MXktlWjsr0%3D 11389070 (Pubitemid 32685769)
12. T Taube I Elomaa C Blomqvist, et al. 1994 Histomorphometric evidence for osteoclast-mediated bone resorption in metastatic breast cancer Bone 15 161 166 10.1016/8756-3282(94)90703-X 1:STN:280:DyaK2czmvVGrsA%3D%3D 8086233 (Pubitemid 24116079)
13. M Kinder EM Chislock KM Bussard, et al. 2008 Metastatic breast cancer induces an osteoblast inflammatory response Exp Cell Res 314 173 183 10.1016/j.yexcr.2007.09.021 1:CAS:528:DC%2BD2sXhtlyrtrvE 17976581 (Pubitemid 350182446)
14. AM Mastro CV Gay DR Welch, et al. 2004 Breast cancer cells induce osteoblast apoptosis: a possible contributor to bone degradation J Cell Biochem 91 265 276 10.1002/jcb.10746 1:CAS:528:DC%2BD2cXhsVSqur4%3D 14743387
15. R Mercer C Miyasaka AM Mastro 2004 Metastatic breast cancer cells suppress osteoblast adhesion and differentiation Clin Exp Metastasis 21 427 435 10.1007/s10585-004-1867-6 1:CAS:528:DC%2BD2MXht1Khsrk%3D 15672867
16. K Black IR Garrett GR Mundy 1991 Chinese hamster ovarian cells transfected with the murine interleukin-6 gene cause hypercalcemia as well as cachexia, leukocytosis and thrombocytosis in tumor-bearing nude mice Endocrinology 128 2657 2659 10.1210/endo-128-5-2657 1:CAS:528:DyaK3MXisVGksbo%3D 2019273
17. Horowitz MC, Lorenzo JA (2002) Principles of bone biology. Academic Press, San Diego
18. N Ferrara K Carver-Moore H Chen, et al. 1996 Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene Nature 380 439 442 10.1038/380439a0 1:CAS:528:DyaK28XitVKqtLk%3D 8602242 (Pubitemid 26102720)
19. I Marriott DL Gray SL Tranguch, et al. 2004 Osteoblasts express the inflammatory cytokine interleukin-6 in a murine model of Staphylococcus aureus osteomyelitis and infected human bone tissue Am J Pathol 164 1399 1406 1:CAS:528:DC%2BD2cXjsFemu7Y%3D 15039227 (Pubitemid 38387805)
20. I Marriott DL Gray D Rati, et al. 2003 Osteoblasts produce monocyte chemoattractant protein-1 in a murine model of osteomyelitis and infected human bone tissue Bone 37 504 512 10.1016/j.bone.2005.05.011
21. R Cailleau M Olive QV Cruciger 1978 Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization In Vitro 14 911 915 10.1007/BF02616120 1:STN:280:DyaE1M%2FoslCqtQ%3D%3D 730202 (Pubitemid 9089089)
22. PA Phadke KS Vaidya KT Nash, et al. 2008 BRMS1 suppresses breast cancer experimental metastasis to multiple organs by inhibiting several steps of the metastatic process Am J Pathol 172 809 817 10.2353/ajpath.2008.070772 1:CAS:528:DC%2BD1cXktVKgsrY%3D 18276787 (Pubitemid 351354552)
23. T Yoneda PJ Williams T Hiraga, et al. 2001 A bone-seeking clone exhibits different biological properties from the MDA-MD-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro J Bone Miner Res 16 1486 1495 10.1359/jbmr.2001.16.8.1486 1:CAS:528:DC%2BD3MXmtVOhur8%3D 11499871 (Pubitemid 32675200)
24. JF Harms LR Budgeon ND Christensen, et al. 2002 Maintaining GFP tissue fluorescence through bone decalcification and long-term storage BioTechniques 33 1197 1200 1:CAS:528:DC%2BD38Xps1enu74%3D 12503297
25. KM Bussard CV Gay AM Mastro 2008 The bone microenvironment in metastasis; what is special about bone? Cancer Metastasis Rev 27 41 55 10.1007/s10555-007- 9109-4 18071636
26. M Bendre DC Montague T Peery, et al. 2003 Interleukin-8 stimulation of osteoclastogenesis and bone resorption is a mechanism for the increased osteolysis of metastatic bone disease Bone 33 28 37 10.1016/S8756-3282(03)00086- 3 1:CAS:528:DC%2BD3sXmt1KjsLw%3D 12919697 (Pubitemid 36952685)
27. TA Guise JM Chirgwin 2003 Transforming growth factor-beta in osteolytic breast cancer bone metastases Clin Orthop Relat Res 415S 532 538
28. A Badache NE Hynes 2001 Interleukin 6 inhibits proliferation and, in cooperation with epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells Cancer Res 61 383 391 1:CAS:528: DC%2BD3MXlsl2quw%3D%3D 11196191 (Pubitemid 32095742)
29. V Goede L Brogelli M Ziche, et al. 1999 Induction of inflammatory angiogenesis by monocyte chemoattractant protein-1 Int J Cancer 82 765 770 10.1002/(SICI)1097-0215(19990827)82:5<765::AID-IJC23>3.0.CO;2-F 1:CAS:528:DyaK1MXltFOitb8%3D 10417778 (Pubitemid 29356979)
30. J Adams PJ Carder S Downey, et al. 2000 Vascular endothelial growth factor (VEGF) in breast cancer: comparison of plasma, serum, and tissue VEGF and microvessel density and effects of tamoxifen Cancer Res 60 2898 2905 1:CAS:528:DC%2BD3cXjvFOltr8%3D 10850435 (Pubitemid 30395813)
31. Y Liang RA Brekken SM Hyder 2006 Vascular endothelial growth factor induces proliferation of breast cancer cells and inhibits the anti-proliferative activity of anti-hormones Endocr Relat Cancer 13 905 919 10.1677/erc.1.01221 1:CAS:528:DC%2BD28Xhtlequr3O 16954439 (Pubitemid 44763266)
32. GD Roodman N Kurihara Y Ohsaki, et al. 1992 Interleukin 6. A potential autocrine/paracrine factor in Paget's disease of bone J Clin Invest 89 46 52 10.1172/JCI115584 1:CAS:528:DyaK38XlslahsA%3D%3D 1729280
33. A Badache NE Hynes 2001 Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells Cancer Res 61 1 383 391 1:CAS:528:DC%2BD3MXlsl2quw%3D%3D 11196191 (Pubitemid 32095742)
34. T Kishimoto 2005 Interleukin-6: from basic science to medicine-40 years in immunology Annu Rev Immunol 23 1 21 10.1146/annurev.immunol.23.021704.115806 1:CAS:528:DC%2BD2MXktFOjtbw%3D 15771564 (Pubitemid 40563163)
35. Fitzgerald KA, O'Neill LAJ, Gearing AJH et al (2001) The cytokine facts book. Academic Press, San Diego
36. DT Graves Y Jiang AJ Valente 1999 The expression of monocyte chemoattractant protein-1 and other chemokines by osteoblasts Front Biosci 4 D571 D580 10.2741/Graves 1:CAS:528:DyaK1MXltFKlsbs%3D 10393126
37. T Ueno M Toi J Saji, et al. 2000 Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer Clin Cancer Res 6 3282 3289 1:CAS:528: DC%2BD3cXmsVOmt7c%3D 10955814 (Pubitemid 30637758)
38. J Tombran-Tink CJ Barnstable 2004 Osteoblasts and osteoclasts express PEDF, VEGF-A isoforms, and VEGF receptors: possible mediators of angiogenesis and matrix remodeling in the bone Biochem Biophys Res Commun 316 573 579 10.1016/j.bbrc.2004.02.076 1:CAS:528:DC%2BD2cXitFKgsr4%3D 15020256 (Pubitemid 38338629)
39. J Wels RN Kaplan S Rafii, et al. 2008 Migratory neighbors and distant invaders: tumor-associated niche cells Genes Dev 22 559 574 10.1101/gad.1636908 1:CAS:528:DC%2BD1cXjsVKnt7s%3D 18316475 (Pubitemid 351342429)
40. D Wang H Wang Y Guo, et al. 2006 Crosstalk between peroxisome proliferator-activated receptor gamma and VEGF stimulates cancer progression Proc Natl Acad Sci USA 103 19069 19074 10.1073/pnas.0607948103 1:CAS:528:DC%2BD28XhtlersrjN 17148604 (Pubitemid 350002829)
41. RN Kaplan B Psaila D Lyden 2006 Bone marrow cells in the 'pre-metastatic niche': within bone and beyond Cancer Metastasis Rev 25 521 529 10.1007/s10555-006-9036-9 17186383 (Pubitemid 46071861)
42. S Paget 1889 The distribution of secondary growths in cancer of the breast Cancer Metastasis Rev 8 98 101
43. Bussard KM (2008) Unpublished observations
44. N Kurihara D Bertolini T Suda, et al. 1990 IL-6 stimulates osteoclast-like multinucleated cell formation in long term human marrow cultures by inducing IL-1 release J Immunol 144 4226 4230 1:CAS:528:DyaK3cXksFOisbY%3D 2341718 (Pubitemid 20187761)
45. Gabrilovich DI, Dikov MM (2003) Vascular endothelial growth factor. In: Thomson AW, Lotze MT (eds) The cytokine handbook, 4th edn. Academic Press, Amsterdam, pp 1017-1034