Observations on the proposed 'nonclassical' model of autoimmune hypothyroidism

Thyroid

Volumn 20, Issue 6, 2010, Pages 665-666

  Nagayama, Yuji ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; FAS LIGAND; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; IODINE; THYROGLOBULIN; THYROID PEROXIDASE; THYROTROPIN RECEPTOR; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE;

ANTIGEN PRESENTATION; APOPTOSIS; AUTOIMMUNE THYROIDITIS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CYTOKINE PRODUCTION; GRAVES DISEASE; HASHIMOTO DISEASE; HUMAN; HYPOTHYROIDISM; IN VITRO STUDY; LETTER; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; THYROID CELL; THYROID FUNCTION; THYROID HORMONE SYNTHESIS; ANIMAL; AUTOIMMUNE DISEASE; BIOLOGICAL MODEL; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; AUTOIMMUNE DISEASES; CYTOKINES; HUMANS; HYPOTHYROIDISM; INTERFERON-GAMMA; MODELS, BIOLOGICAL; THYROIDITIS, AUTOIMMUNE;

EID: 77953949956     PISSN: 10507256     EISSN: None     Source Type: Journal    
DOI: 10.1089/thy.2010.0039     Document Type: Letter

References (17)

1. Caturegli P, Kimura H 2010 A nonclassical model of autoimmune hypothyroidism. Thyroid 20:3-5.
2. Caturegli P, Hejazi M, Suzuki K, Dohan O, Carrasco N, Kohn LD, Rose NR 2000 Hypothyroidism in transgenic mice expressing IFN-gamma in the thyroid. Proc Natl Acad Sci USA 97:1719-1724.
3. Nagayama Y, Izumi M, Ashizawa K, Kiriyama T, Yokoyama N, Morita S, Ohtakara S, Fukuda T, Eguchi K, Morimoto I, Okamoto S, Ishikawa N, Ito K, Nagataki S 1987 Inhibitory effect of interferon-gamma on the response of human thyrocytes to thyrotropin (TSH) stimulation: relationship between the response to TSH and the expression of DR antigen. J Clin Endocrinol Metab 64:949-953.
4. Yamashita S, Kimura H, Ashizawa K, Nagayama Y, Hirayu H, Izumi M, Nagataki S 1989 Interleukin-1 inhibits thyrotrophin-induced human thyroglobulin gene expression. J Endocrinol 122:177-183.
5. Ashizawa K, Yamashita S, Nagayama Y, Kimura H, Hirayu H, Izumi M, Nagataki S 1989 Interferon-gamma inhibits thyrotropin-induced thyroidal peroxidase gene expression in cultured human thyrocytes. J Clin Endocrinol Metab 69: 475-477.
6. Ashizawa K, Yamashita S, Tobinaga T, Nagayama Y, Kimura H, Hirayu H, Izumi M, Nagataki S 1989 Inhibition of human thyroid peroxidase gene expression by interleukin 1. Acta Endocrinol (Copenh) 121:465-469.
7. Tominaga T, Yamashita S, Nagayama Y, Morita S, Yokoyama N, Izumi M, Nagataki S 1991 Interleukin 6 inhibits human thyroid peroxidase gene expression. Acta Endocrinol (Copenh) 124:290-294.
8. Nishikawa T, Yamashita S, Namba H, Usa T, Tominaga T, Kimura H, Izumi M, Nagataki S 1993 Interferon-gamma inhibition of human thyrotropin receptor gene expression. J Clin Endocrinol Metab 77:1084-1089. (Pubitemid 23301490)
9. Sato K, Satoh T, Shizume K, Ozawa M, Han DC, Imamura H, Tsushima T, Demura H, Kanaji Y, Ito Y, Obara T, Fujimoto Y, Kanaji Y 1990 Inhibition of 125I organification and thyroid hormone release by interleukin-1, tumor necrosis factor-alpha, and interferon-gamma in human thyrocytes in suspension culture. J Clin Endocrinol Metab 70:1735-1743.
10. Sato K, Yamazaki K, Shizume K, Yamakawa Y, Satoh T, Demura H, Kanaji Y, Obara T, Fujimoto Y, Aiba M, Kakiuchi T, Kanaji Y 1993 Pathogenesis of autoimmune hypothyroidism induced by lymphokine-activated killer (LAK) cell therapy: in vitro inhibition of human thyroid function by interleukin-2 in the presence of autologous intrathyroidal lymphocytes. Thyroid 3:179-188.
11. Yamazaki K, Kanaji Y, Shizume K, Yamakawa Y, Demura H, Kanaji Y, Obara T, Sato K 1993 Reversible inhibition by interferons alpha and beta of 125I incorporation and thyroid hormone release by human thyroid follicles in vitro. J Clin Endocrinol Metab 77:1439-1441.
12. Fentiman IS, Thomas BS, Balkwill FR, Rubens RD, Hayward JL 1985 Primary hypothyroidism associated with interferon therapy of breast cancer. Lancet 1:1166.
13. Burman P, Karlsson FA, Oberg K, Alm G 1985 Autoimmune thyroid disease in interferon-treated patients. Lancet 2:100.
14. Tomer Y, Blackard JT, Akeno N 2007 Interferon alpha treatment and thyroid dysfunction. Endocrinol Metab Clin North Am 36:1051-1066.
15. Boehm U, Klamp T, Groot M, Howard JC 1997 Cellular responses to interferon-gamma. Annu Rev Immunol 15: 749-795.
16. Fang Y, Yu S, Braley-Mullen H 2007 Contrasting roles of IFM-g in murine models of autoimmune thyroid disease. Thyroid 17:989-994.
17. Stassi G, Di Liberto D, Todaro M, Zeuner A, Ricci-Vitiani L, Stoppacciaro A, Ruco L, Farina F, Zummo G, De Maria R 2000 Control of target cell survival in thyroid autoimmunity by T helper cytokines via regulation of apoptotic proteins. Nat Immunol 1:483-488.