Angiotensin-converting enzyme 2 autoantibodies: Further evidence for a role of the renin-angiotensin system in inflammation

Arthritis Research and Therapy

Volumn 12, Issue 3, 2010, Pages

  Chappell, Mark C ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE ANTAGONIST; ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN CONVERTING ENZYME 2 AUTOANTIBODY; ANGIOTENSIN I; ANGIOTENSIN II; AUTOANTIBODY; DIPEPTIDYL CARBOXYPEPTIDASE; UNCLASSIFIED DRUG; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN I (1 7); ANGIOTENSIN I (1-7); PEPTIDE FRAGMENT;

AUTOIMMUNITY; CELL FUNCTION; CONNECTIVE TISSUE DISEASE; EDITORIAL; ENCEPHALOCELE; ENZYME ACTIVITY; HEART FAILURE; HUMAN; INFLAMMATION; PREECLAMPSIA; PROTEIN EXPRESSION; PULMONARY HYPERTENSION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SYSTEMIC SCLEROSIS; VASCULAR DISEASE; BLOOD; HYPERTENSION; IMMUNOLOGY; NOTE; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANGIOTENSIN I; ANGIOTENSIN II; AUTOANTIBODIES; HUMANS; HYPERTENSION; PEPTIDE FRAGMENTS; PEPTIDYL-DIPEPTIDASE A; RECEPTOR, ANGIOTENSIN, TYPE 1; RENIN-ANGIOTENSIN SYSTEM; SCLERODERMA, SYSTEMIC;

EID: 77953946704     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar3052     Document Type: Editorial

References (10)

1. Takahashi Y, Haga S, Ishizaka Y, Mimori A. Autoantibodies to angiotensin converting enzyme 2 in patients with connective tissue diseases. Arthritis Res Ther 2010, 12:R85. 10.1186/ar3012, 20470389.
2. Chappell MC. Emerging evidence for a functional angiotensin-converting enzyme 2-angiotensin-(1-7) mas receptor axis; more than regulation of blood pressure?. Hypertension 2007, 50:596-599. 10.1161/HYPERTENSIONAHA.106.076216, 17785634.
3. Rice GI, Jones AL, Grant PJ, Carter AM, Turner AJ, Hooper NM. Circulating activities of angiotensin-converting enzyme, its homolog, angiotensin-converting enzyme 2, and neprilysin in a family study. Hypertension 2006, 48:914-920. 10.1161/01.HYP.0000244543.91937.79, 17000927.
4. Epelman S, Tang WHW, Chen SY, Van Lente F, Francis GS, Sen S. Detection of soluble angiotensin-converting enzyme 2 in heart failure: insights into the endogenous counter-regulatory pathway of the renin-angiotensin-aldosterone system. J Am Coll Cardiol 2008, 52:750-754. 2856943, 18718423, 10.1016/j.jacc.2008.02.088.
5. Verlohren S, Muller DN, Luft FC, Dechend R. Immunology in hypertension, preeclampsia, and target-organ damage. Hypertension 2009, 54:439-443. 10.1161/HYPERTENSIONAHA.108.120253, 19597043.
6. Hoch NE, Guzik TJ, Chen W, Deans T, Maalouf SA, Gratze P, Weyand C, Harrison DG. Regulation of T-cell function by endogenously produced angiotensin II. Am J Physiol Regul Integr Comp Physiol 2009, 296:R208-R216. 2643984, 19073907.
7. Platten M, Youssef S, Hur EM, Ho PP, Han MH, Lanz TV, Phillips LK, Goldstein MJ, Bhat R, Raine CS, Sobel RA, Steinman L. Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17- mediated autoimmunity. Proc Natl Acad Sci USA 2009, 106:14948-14953. 2736463, 19706421, 10.1073/pnas.0903958106.
8. Oudit GY, Liu GC, Zhong J, Basu R, Chow FL, Zhou J, Loibner H, Janzek E, Schuster M, Penninger JM, Herzenberg AM, Kassiri Z, Scholey JW. Human recombinant ACE2 reduces the progression of diabetic nephropathy. Diabetes 2010, 59:529-538. 10.2337/db09-1218, 19934006.
9. Osterreicher CH, Taura K, De Minicis S, Seki E, Penz-Osterreicher M, Kodama Y, Kluwe J, Schuster M, Oudit GY, Penninger JM, Brenner DA. Angiotensinconverting- enzyme 2 inhibits liver fibrosis in mice. Hepatology 2009, 50:929-938. 10.1002/hep.23104, 19650157.
10. Yamazato Y, Ferreira AJ, Hong KH, Sriramula S, Francis J, Yamazato M, Yuan L, Bradford CN, Shenoy V, Oh SP, Katovich MJ, Raizada MK. Prevention of pulmonary hypertension by angiotensin-converting enzyme 2 gene transfer. Hypertension 2009, 54:365-371. 10.1161/HYPERTENSIONAHA.108.125468, 19564552.