Preferential patterns of myocardial iron overload by multislice multiecho T2* CMR in thalassemia major patients

Magnetic Resonance in Medicine

Volumn 64, Issue 1, 2010, Pages 211-219

  Meloni, Antonella ^a   Positano, Vincenzo ^a   Pepe, Alessia ^a   Rossi, Giuseppe ^a   Dell'Amico, MariaChiara ^a   Salvatori, Cristina ^a   Keilberg, Petra ^a   Filosa, Aldo ^b   Sallustio, Giuseppina ^c   Midiri, Massimo ^d   D'Ascola, Domenico ^e   Santarelli, Maria Filomena ^a   Lombardi, Massimo ^a  

^a INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^b CARDARELLI HOSPITAL   (Italy)

^c CATHOLIC UNIVERSITY   (Italy)

^d UNIVERSITY OF PALERMO   (Italy)

^e BIANCHI MELACRINO MORELLI HOSPITAL   (Italy)

Author keywords

Cardiovascular magnetic resonance; Multislice multiecho T2*; Myocardial iron overload; Preferential pattern; Thalassemia major

Indexed keywords

IRON DEPOSITS;

CARDIOVASCULAR MAGNETIC RESONANCES; IRON OVERLOADS; MULTI SLICES; PREFERENTIAL PATTERN; THALASSEMIA MAJOR;

MAGNETIC RESONANCE;

ADOLESCENT; ADULT; ARTICLE; ARTIFACT; CHILD; DIAGNOSTIC APPROACH ROUTE; DISEASE SEVERITY; FEMALE; HEART HEMOSIDEROSIS; HEART LEFT VENTRICLE; HEART MUSCLE; HEART VENTRICLE SEPTUM; HUMAN; IRON STORAGE; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; SCHOOL CHILD; THALASSEMIA MAJOR; BETA THALASSEMIA; HEART; IRON OVERLOAD; MIDDLE AGED; PATHOLOGY; RADIOGRAPHY; RETROSPECTIVE STUDY;

ADOLESCENT; ADULT; BETA-THALASSEMIA; CHILD; FEMALE; HEART; HUMANS; IRON OVERLOAD; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MYOCARDIUM; RETROSPECTIVE STUDIES;

EID: 77953933212     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.22410     Document Type: Article

References (32)

1. Borgna-Pignatti C, Cappellini MD, De Stefano P, Del Vecchio GC, Forni GL, Gamberini MR, Ghilardi R, Origa R, Piga A, Romeo MA, Zhao H, Cnaan A. Survival and complications in thalassemia. Ann N Y Acad Sci 2005;1054:40-47.
2. Aldouri MA, Wonke B, Hoffbrand AV, Flynn DM, Ward SE, Agnew JE, Hilson AJ. High incidence of cardiomyopathy in betathalassaemia patients receiving regular transfusion and iron chelation: reversal by intensified chelation. Acta Haematol 1990;84:113-117. (Pubitemid 20361934)
3. Wacker P, Halperin DS, Balmer-Ruedin D, Oberhansli I, Wyss M. Regression of cardiac insufficiency after ambulatory intravenous deferoxamine in thalassemia major. Chest 1993;103:1276-1278. (Pubitemid 23110317)
4. Davis BA, Porter JB. Long-term outcome of continuous 24-hour deferoxamine infusion via indwelling intravenous catheters in high-risk beta-thalassemia. Blood 2000;95:1229-1236.
5. Gossuin Y, Roch A, Muller RN, Gillis P. Relaxation induced by ferritin and ferritin-like magnetic particles: the role of proton exchange. Magn Reson Med 2000;43:237-243. (Pubitemid 30075446)
6. Brooks RA, Vymazal J, Goldfarb RB, Bulte JW, Aisen P. Relaxometry and magnetometry of ferritin. Magn Reson Med 1998;40:227-235.
7. St Pierre TG, Clark PR, Chua-Anusorn W. Single spin-echo proton transverse relaxometry of iron-loaded liver. NMR Biomed 2004;17:446-458.
8. 2*) magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J 2001;22:2171-2179.
9. 2*. Eur J Haematol 2006;76:183-192.
10. 2* cardiovascular magnetic resonance technique for diagnosis of myocardial iron overload. J Magn Reson Imaging 2003;18:33-39.
11. Olson LJ, Edwards WD, Holmes DR Jr, Miller FA Jr, Nordstrom LA, Baldus WP. Endomyocardial biopsy in hemochromatosis: clinicopathologic correlates in six cases. J Am Coll Cardiol 1989;13:116-120.
12. Olson LJ, Edwards WD, McCall JT, Ilstrup DM, Gersh BJ. Cardiac iron deposition in idiopathic hemochromatosis: histologic and analytic assessment of 14 hearts from autopsy. J Am Coll Cardiol 1987;10:1239-1243.
13. 2* cardiovascular magnetic resonance for detection of the heterogeneous distribution of myocardial iron overload. J Magn Reson Imaging 2006;23:662-668.
14. Ramazzotti A, Pepe A, Positano V, Rossi G, De Marchi D, Brizi MG, Luciani A, Midiri M, Sallustio G, Valeri G, Caruso V, Centra M, Cianciulli P, De Sanctis V, Maggio A, Lombardi M. Multicenter validation of the magnetic resonance T2z.ast; technique for segmental and global quantification of myocardial iron. J Magn Reson Imaging 2009;30:62-68.
15. 2* cardiac magnetic resonance for the detection of heterogeneous myocardial iron distribution in thalassaemia patients. NMR Biomed 2009;22:707-715.
16. 2* values in thalassemia patients. J Magn Reson Imaging 2009;29:832-837.
17. 2* MRI assessment of iron overload in thalassemia. Int J Med Inform 2009;78:503-512.
18. 2* segmental artefacts. NMR Biomed 2007;20:578-590.
19. Cerqueira MD, Weissman NJ, Dilsizian V, Jacobs AK, Kaul S, Laskey WK, Pennell DJ, Rumberger JA, Ryan T, Verani MS. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: a statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Circulation 2002;105:539-542.
20. Pennell DJ. T2* magnetic resonance and myocardial iron in thalassemia. Ann N Y Acad Sci 2005;1054:373-378. (Pubitemid 43031044)
21. Jensen PD, Jensen FT, Christensen T, Heickendorff L, Jensen LG, Ellegaard J. Indirect evidence for the potential ability of magnetic resonance imaging to evaluate the myocardial iron content in patients with transfusional iron overload. MAGMA 2001;12:153-166.
22. Ghugre NR, Enriquez CM, Gonzalez I, Nelson MD Jr, Coates TD, Wood JC. MRI detects myocardial iron in the human heart. Magn Reson Med 2006;56:681-686. (Pubitemid 44338890)
23. Ghugre NR, Enriquez CM, Coates TD, Nelson MD Jr, Wood JC. Improved R2* measurements in myocardial iron overload. J Magn Reson Imaging 2006;23:9-16.
24. Reeder SB, Faranesh AZ, Boxerman JL, McVeigh ER. In vivo measurement of T*2 and field inhomogeneity maps in the human heart at 1.5 T. Magn Reson Med 1998;39:988-998.
25. Anderson DJ, Dendy JM, Paschal CB. Simulation study of susceptibility gradients leading to focal myocardial signal loss. J Magn Reson Imaging 2008;28:1402-1408.
26. 2* measurements in myocardial siderosis in thalassemia. Magn Reson Med 2009;61:501-506.
27. Anderson LJ, Wonke B, Prescott E, Holden S, Walker JM, Pennell DJ. Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia. Lancet 2002;360:516-520. (Pubitemid 35232104)
28. Cogliandro T, Derchi G, Mancuso L, Mayer MC, Pannone B, Pepe A, Pili M, Bina P, Cianciulli P, De Sanctis V, Maggio A. Guideline recommendations for heart complications in thalassemia major. J Cardiovasc Med (Hagerstown) 2008;9:515-525.
29. 2* measurements of tissue iron in thalassemia. J Magn Reson Imaging 2003;18:616-620.
30. Wood JC, Tyszka JM, Carson S, Nelson MD, Coates TD. Myocardial iron loading in transfusion-dependent thalassemia and sickle cell disease. Blood 2004;103:1934-1936. (Pubitemid 38268994)
31. 2* mapping free of distortion using susceptibility-weighted fast spin-echo imaging: a feasibility study at 1.5 T and 3.0 T. Magn Reson Med 2009;62:822-828.
32. 2* and lipid measurement at 3.0 T-initial experience. Eur Radiol 2008;18:800-805.