Selection and optimization of a high-producing tissue culture of Panax ginseng C. A. Meyer

Acta Physiologiae Plantarum

Volumn 32, Issue 4, 2010, Pages 765-772

  Huang, T ^a   Gao, Wen Yuan ^a,b   Wang, J ^a   Cao, Y ^b   Zhao, Y X ^c   Huang, L Q ^d   Liu, C X ^a  

^a TIANJIN UNIVERSITY   (China)

^b TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c JILIN AGRICULTURAL UNIVERSITY   (China)

^d INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

Adventitious roots; Ginsenosides; Hairy roots; Panax ginseng; Polysaccharides

Indexed keywords

PANAX GINSENG;

EID: 77953873722     PISSN: 01375881     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11738-010-0461-6     Document Type: Article

References (24)

1. Chen JH, Xie MY, Nie SP et al (2005) Determination of polysaccharides in Panax quinquefolium L. J Food Sci Biotechnol 24(5): 72-76.
2. Chen W, Guo XH, Gao WY et al (2006) Studies on in vitro culture of adventitious root in Salvia miltiorrhiza. China J Chin Materia Medica 31(17): 1409-1412.
3. Choi KT, Ahn IK, Park JC (1994) Production of ginseng saponin in tissue culture of ginseng (Panax ginseng C. A. Meyer). Russ J Plant Physiol 41: 784-788.
4. Fang CY (2005) The study of polysaccharide of ginseng cell cultured and natural ginseng [D]. Master's Degree, Jilin University.
5. Gao WY, Jia W, Duan HQ et al (2003) Industrialization of medicinal plant tissue culture. China J Chin Materia Medica 28: 385-390 (in Chinese).
6. Guo XH, Gao WY, Xiao PG (2005) Factors affecting root growth and metabolite production in Salvia miltiorrhiza adventitious root cultures. Minerva Biotechnol 17: 133-140.
7. Kim YS, Hahn EJ, Yeung EC, Paek EY (2003) Lateral root development and saponin accumulation as affected by IBA or NAA in adventitious root cultures of Panax ginseng C. A. Meyer. In Vitro Cell Dev Biol Plant 39: 245-249.
8. Kim JH, Chang EJ, Oh HI (2005) Saponin production in submerged adventitious root culture of Panax ginseng as affected by culture conditions and elicitors. Asia Pac J Mol Biol Biotechnol 13(2): 87-91.
9. Kronzucker HJ, Siddiqi MY, Glass ADM, Kirk GJD (1999) Nitrate-ammonium synergism in rice: a subcellular flux analysis. Plant Physiol 119: 1041-1045.
10. Langhansová L, Maršík P, Vaněk T (2005) Production of saponins from Panax ginseng suspension and adventitious root cultures. Biol Plant 49(3): 463-465.
11. Liu S, Zhong JJ (1998) Phosphate effect on production of ginseng saponin and polysaccharide by cell suspension cultures of Panax ginseng and Panax quinquefolium. Process Bioechem 33: 69-74.
12. Paek KY, Chakrabarty D, Hahn EJ (2005) Application of bioreactor systems for large scale production of horticultural and medicinal plants. Plant Cell Tissue Organ Cult 81: 287-300.
13. Paek KY, Murthy HN, Hahn EJ, Zhong JJ (2008) Large scale culture of ginseng adventitious roots for production of ginsenosides. Adv Biochem Eng/Biotechnol. doi: 10. 1007/10_2008_31.
14. Pinto G, Silva S, Park YS et al (2008) Factors influencing somatic embryogenesis induction in Eucalyptus globules Labill.: basal medium and anti-browning agents. Plant Cell Tissue Organ Cult 95: 79-88.
15. Sivakumar G, Yu KW, Paek KY (2005) Production of biomass and ginsenosides from adventitious roots of Panax ginseng in bioreactor cultures. Eng Life Sci 5(4): 333-342.
16. Slightom JL, Mylene DT, Lise J et al (1986) Nucleotide sequence analysis of T-DNA of Agrobacterium rhizogenes agropine type plasmid identification of open reading frames. J Biol Chem 261(1): 108-121.
17. Wang J, Gao WY, Cao Y, Huang T (2009) Effects of carbon, nitrogen and phosphate sources on biomass and active components of suspension cells in Panax quinquefolium L. Chin Pharm J 44(11): 815-818.
18. Wu J, Zhong JJ (1999) Production of ginseng and its bioactive components in plant cell culture: current technological and applied aspects. J Biotechnol 68: 89-99. doi: 10. 1016/S0168-1656(98)00195-3.
19. Yu KW, Murthy HN, Hahn EJ, Paek KY (2005) Ginsenoside production by hairy root cultures of Panax ginseng: influence of temperature and light quality. Biochem Eng J 23: 53-56. doi: 10. 1016/j. bej. 2004. 07. 001.
20. Zhang YH, Zhong JJ (1997) Hyperproduction of ginseng saponin and polysaccharide by high density cultivation of Panax notoginseng cells. Enzyme Microb Technol 21: 59-63.
21. Zhang YH, Zhong JJ, Yu JT (1995) Effect of osmotic pressure on cell growth and production of ginseng saponin and polysaccharide in suspension cultures of Panax notoginseng. Biotechnol Lett 17: 1347-1350.
22. Zhang YH, Zhong JJ, Yu JT (1996) Effect of nitrogen source on cell growth and production of ginseng saponin and polysaccharide in suspension cultures of Panax notoginseng. Biotechnol Prog 12: 567-571.
23. Zhao SJ, Li CY, Qian YC, Luo XP, Zhang X, Wang XS, Kang BY (2004) Induction of hairy roots of Panax ginseng and studies on suitable culture condition of ginseng hairy roots. Chin J Biotechnol 20: 215-220.
24. Zhou LG, Cao XD, Zhang RF, Peng YL, Zhao SJ, Wu JY (2007) Stimulation of saponin production in Panax ginseng hairy roots by two oligosaccharides from Paris polyphylla var. yunnanensis. Biotechnol Lett 29: 631-634.