Antibodies against N-methyl-D-aspartate receptors in patients with systemic lupus erythematosus without major neuropsychiatric syndromes

Journal of the Neurological Sciences

Volumn 295, Issue 1-2, 2010, Pages 87-91

  Kozora, Elizabeth ^a,b   West, Sterling G ^b   Maier, Steven F ^c   Filley, Christopher M ^b,d   Arciniegas, David B ^b   Brown, Mark ^b   Miller, David ^b   Grimm, Alex ^b   Zhang, Lening ^a,b  

^a DEPARTMENT OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO HOSPITAL   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Auto antibodies; Neuropsychology; NMDA; SLE

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR ANTIBODY; RECEPTOR ANTIBODY; UNCLASSIFIED DRUG;

ADULT; ANTIBODY BLOOD LEVEL; APTITUDE TEST; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; EDUCATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MALE; MEMORY DISORDER; PATIENT; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS; VERBAL MEMORY; WORKING MEMORY;

ACETYLCHOLINE; ADOLESCENT; ADULT; ANTIBODIES; COGNITION DISORDERS; FEMALE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PROSPECTIVE STUDIES; RECEPTORS, N-METHYL-D-ASPARTATE; YOUNG ADULT;

EID: 77953872524     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2010.04.016     Document Type: Article

References (48)

1. West S.G. The nervous system. In: Wallace D.J., and Hahn B.H. (Eds). Dubois' lupus erythematosus. Seventh ed. (2007), Lippincott, Williams & Wilkins, Philadelphia 707-746
2. Westaby S., Saatvedt K., White S., Katsumata T., and van Oeveren W. Is there a relationship between serum S-100B protein and neuropsychologic dysfunction after cardiopulmonary bypass?. J Thorac Cardiovasc Surg 119 (2000) 132-137 al. e.
3. Brey R.L., Holliday S.L., Saklad A.R., Navarrete M.G., Hermosillo-Romo D., Stallworth C.L., et al. Neuropsychiatric syndromes in lupus: prevalence using standardized definitions. Neurology 58 8 (2002) 1214-1220 Apr 23
4. Carbotte R.M., Denburg S.D., and Denburg J.A. Prevalence of cognitive impairment in systemic lupus erythematosus. J Nerv Ment Dis 174 6 (1986) 357-364
5. Denburg S.D., Carbotte R.M., and Denburg J.A. Cognitive impairment in systemic lupus erythematosus: a neuropsychological study of individual and group deficits. J Clin Exp Neuropsychol 9 4 (1987) 323-339
6. Hanly J.G., Fisk J.D., Sherwood G., Jones E., Jones J.V., and Eastwood B. Cognitive impairment in patients with systemic lupus erythematosus. J Rheumatol 19 4 (1992) 562-567
7. Hay E.M., Black D., Huddy A., Creed F., Tomenson B., Bernstein R.M., et al. Psychiatric disorder and cognitive impairment in systemic lupus erythematosus. Arthritis Rheum 35 4 (1992) 411-416
8. Kozora E., Thompson L.L., West S.G., and Kotzin B.L. Analysis of cognitive and psychological deficits in systemic lupus erythematosus patients without overt central nervous system disease. Arthritis Rheum 39 12 (1996) 2035-2045
9. Wekking E.M., Nossent J.C., van Dam A.P., and Swaak A.J. Cognitive and emotional disturbances in systemic lupus erythematosus. Psychother Psychosom 55 2-4 (1991) 126-131
10. Carlomagno S., Migliaresi S., Ambrosone L., Sannino M., Sanges G., and Di Iorio G. Cognitive impairment in systemic lupus erythematosus: a follow-up study. J Neurol 247 4 (2000) 273-279
11. Monastero R., Bettini P., Del Zotto E., Cottini E., Tincani A., Balestrieri G., et al. Prevalence and pattern of cognitive impairment in systemic lupus erythematosus patients with and without overt neuropsychiatric manifestations. J Neurol Sci 184 1 (2001) 33-39
12. Kozora E., Ellison M.C., and West S. Reliability and validity of the proposed American College of Rheumatology neuropsychological battery for systemic lupus erythematosus. Arthritis Rheum 51 5 (2004) 810-818 Oct 15
13. Kozora E., Arciniegas D.B., Filley C.M., West S.G., Brown M., Miller D., et al. Cognitive and neurologic status in patients with systemic lupus erythematosus without major neuropsychiatric syndromes. Arthritis Rheum 59 11 (2008) 1639-1646 Nov 15
14. Roebuck-Spencer T.M., Yarboro C., Nowak M., Takada K., Jacobs G., Lapteva L., et al. Use of computerized assessment to predict neuropsychological functioning and emotional distress in patients with systemic lupus erythematosus. Arthritis Rheum 55 3 (2006) 434-441 Jun 15
15. Utset T.O., Fink J., and Doninger N.A. Prevalence of neurocognitive dysfunction and other clinical manifestations in disabled patients with systemic lupus erythematosus. J Rheumatol 33 3 (2006) 531-538 Mar
16. Ginsburg K.S., Wright E.A., Larson M.G., Fossel A.H., Albert M., Schur P.H., et al. A controlled study of the prevalence of cognitive dysfunction in randomly selected patients with systemic lupus erythematosus. Arthritis Rheum 35 7 (1992) 776-782
17. Hanly J.G., Walsh N.M., Fisk J.D., Eastwood B., Hong C., Sherwood G., et al. Cognitive impairment and autoantibodies in systemic lupus erythematosus. Br J Rheumatol 32 4 (1993) 291-296 Apr
18. Carbotte R.M., Denburg S.D., and Denburg J.A. Cognitive dysfunction in systemic lupus erythematosus is independent of active disease. J Rheumatol 22 5 (1995) 863-867 May
19. Sailer M., Burchert W., Ehrenheim C., Smid H.G.O.M., Haas J., Wildhagen K., et al. Positron emission tomography and magnetic resonance imaging for cerebral involvement in patients with systemic lupus erythematosus. J Neurol 244 3 (1997) 186-193
20. Glanz B.I., Slonim D., Urowitz M.B., Gladman D.D., Gough J., Math M., et al. Pattern of neuropsychologic dysfunction in inactive systemic lupus erythematosus. Neuropsychiatry Neuropsychol Behav Neurol 10 4 (1997) 232-238
21. Waterloo K., Omdal R., Husby G., and Mellgren S.I. Neuropsychological function in systemic lupus erythematosus: a five-year longitudinal study. Rheumatology (Oxford) 41 4 (2002) 411-415
22. Tomietto P., Annese V., D'Agostini S., Venturini P., La Torre G., De Vita S., et al. General and specific factors associated with severity of cognitive impairment in systemic lupus erythematosus. Arthritis Rheum 57 8 (2007) 1461-1472 Dec 15
23. Hanly J.G., Kuznetsova A., and Fisk J.D. Psychopathology of lupus and neuroimaging. In: Wallace D.J., and HaHn B.H. (Eds). Dubois' lupus erythematosus. Seventh ed (2007), Lippincott, Williams & Wilkins, Philadelphia
24. DeGiorgio L.A., Konstantinov K.N., Lee S.C., Hardin J.A., Volpe B.T., and Diamond B. A subset of lupus anti-DNA antibodies cross-reacts with the NR2 glutamate receptor in systemic lupus erythematosus. Nat Med 7 11 (2001) 1189-1193
25. Kowal C., DeGiorgio L.A., Nakaoka T., Diamond B., and Volpe B. Cognition and immunity: antibody inpairs memory. Immunity 21 (2004) 179-188 (August)
26. Harrison M.J., Ravdin L.D., and Lockshin M.D. Relationship between serum NR2a antibodies and cognitive dysfunction in systemic lupus erythematosus. Arthritis Rheum 54 8 (2006) 2515-2522 Aug
27. Lapteva L., Nowak M., Yarboro C.H., Takada K., Roebuck-Spencer T., Weickert T., et al. Anti-N-methyl-D-aspartate receptor antibodies, cognitive dysfunction, and depression in systemic lupus erythematosus. Arthritis Rheum 54 8 (2006) 2505-2514 Aug
28. Hanly J.G., Robichaud J., and Fisk J.D. Anti-NR2 glutamate receptor antibodies and cognitive function in systemic lupus erythematosus. J Rheumatol 33 8 (2006) 1553-1558 Aug
29. Omdal R., Brokstad K., Waterloo K., Koldingsnes W., Jonsson R., and Mellgren S.I. Neuropsychiatric disturbances in SLE are associated with antibodies against NMDA receptors. Eur J Neurol 12 5 (2005) 392-398 May
30. The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes. Arthritis Rheum 42 4 (1999) 599-608
31. Hochberg M.C. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis & Rheum 40 9 (1997) 1725
32. Bombardier C., Gladman D.D., Urowitz M.B., Caron D., and Chang C.H. Derivation of the SLEDAI. A disease activity index for lupus patients. The committee on prognosis studies in SLE. Arthritis Rheum 35 6 (1992) 630-640
33. First M.B., Spitzer R.L., Givvon M., and Williams J.B. Structured clinical interview for DSM-IV axis i disorders (SCID-1)-clinical version (1997), New York State Psychiatric Institute, New York, NY
34. Wechsler D. Weschler test of adult reading (2001), The Psychological Corporation, San Antonio
35. Wechsler D. Wechsler adult intelligence scale - revised manual (1981), Psychological Corporation, Inc., San Antonio, Texas
36. Reitan R.M., and Wolfson D. The Halstead-Reitan neuropsychology test battery (1988), Neuropsychological Press, Tucson
37. Golden C.J. Stroop color and word test (1978), Stoelting, Chicago
38. Delis D, Kramer J, Kaplan E, Ober B. California Verbal Learning Test-Second Edition. Corporation TP, editor. San Antonio, TX: The Psychological Corporation; 2000.
39. Meyers J.E., and Meyers K.R. Rey complex figure test and recognition trial: professional manual (1995), Psychological Assessment Resources, Inc., Odessa, Florida
40. Wechsler D. Wechsler adult intelligence scale-third edition (1997), Psychological Corporation, Inc., San Antonio, Texas
41. Borkowski J.G., Benton A.L., and Spreen O. Word fluency and brain damage. Neuropsychologia 5 (1967) 135-140
42. Beck A.T., Steer R.A., and Brown G.K. Manual for Beck Depression Inventory-II (1996), The Psychological Corporation, San Antonio
43. Steup-Beekman G., Steens S., van Buchem M., and Huizinga T. Anti-NMDA receptor autoantibodies in patients with systemic lupus erythematosus and their first-degree relatives. Lupus 16 5 (2007) 329-334
44. Filley C.M. Exploring white matter microstructure: new insights from diffusion tensor imaging. Neurology 73 21 (2009) 1718-1719 Nov 24
45. Arinuma Y., Yanagida T., and Hirohata S. Association of cerebrospinal fluid anti-NR2 glutamate receptor antibodies with diffuse neuropsychiatric systemic lupus erythematosus. Arthritis Rheum 58 4 (2008) 1130-1135 Apr
46. Yoshio T., Onda K., Nara H., and Minota S. Association of IgG anti-NR2 glutamate receptor antibodies in cerebrospinal fluid with neuropsychiatric systemic lupus erythematosus. Arthritis Rheum 54 2 (2006) 675-678 Feb
47. Fragoso-Loyo H., Cabiedes J., Orozco-Narvaez A., Davila-Maldonado L., Atisha-Fregoso Y., Diamond B., et al. Serum and cerebrospinal fluid autoantibodies in patients with neuropsychiatric lupus erythematosus. Implications for diagnosis and pathogenesis. PLoS ONE 3 10 (2008) e3347
48. Kowal C., Degiorgio L.A., Lee J.Y., Edgar M.A., Huerta P.T., Volpe B.T., et al. Human lupus autoantibodies against NMDA receptors mediate cognitive impairment. Proc Natl Acad Sci U S A 103 52 (2006 Dec 26) 19854-19859