Treatment with botulinum toxin improves the hyperexcitability of the facial motoneuron in patients with hemifacial spasm

Neurological Research

Volumn 32, Issue 6, 2010, Pages 656-660

  Ishikawa, Mami ^a   Takashima, Koichi ^a   Kamochi, Haruna ^a   Kusaka, Gen ^a   Shinoda, Sohji ^a   Watanabe, Eiju ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

ABNORMAL MUSCLE RESPONSE; BLINK REFLEX; BOTULINUM TOXIN; F WAVE; HEMIFACIAL SPASM

Indexed keywords

BOTULINUM TOXIN A; MUSCLE RELAXANT AGENT;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; HEMIFACIAL SPASM; HUMAN; MALE; MOTONEURON; ORBICULARIS OCULI MUSCLE; TREATMENT DURATION; BLINKING; CLINICAL TRIAL; DRUG EFFECTS; ELECTROSTIMULATION; EVOKED RESPONSE; FACIAL NERVE; FOLLOW UP; MIDDLE AGED; PATHOLOGY; PROCEDURES; TIME; VERY ELDERLY;

AGED; AGED, 80 AND OVER; BLINKING; BOTULINUM TOXINS, TYPE A; ELECTRIC STIMULATION; EVOKED POTENTIALS; FACIAL NERVE; FEMALE; FOLLOW-UP STUDIES; HEMIFACIAL SPASM; HUMANS; MALE; MIDDLE AGED; MOTOR NEURONS; NEUROMUSCULAR AGENTS; TIME FACTORS;

EID: 77953842043     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1179/174313209X431129     Document Type: Article

References (17)

1. Ogawara K, Kuwabara S, Kamitsukasa I, et al. Trigeminal afferent input alters the excitability of facial motoneurons in hemifacial spasm. Neurology 2004; 62: 1749-1752
2. Lorenzano C, Bagnato S, Gilio F, et al. No clinical or neurophysiological evidence of botulinum toxin diffusion to non-injected muscles in patients with hemifacial spasm. Neurotox Res 2006; 9: 141-144
3. Ishikawa M, Ohira T, Namiki J, et al. Electrophysiological investigation of hemifacial spasm: F-waves of the facial muscles. Acta Neurochir (Wien) 1996; 138: 24-32
4. Ishikawa M, Ohira T, Namiki J, et al. F-wave in patients with hemifacial spasm: Observations during microvascular decompression operations. Neurol Res 1996; 18: 2-8 (Pubitemid 26060381)
5. Ishikawa M, Ohira T, Namiki J, et al. Abnormal muscle response (lateral spread) and F-wave in patients with hemifacial spasm. J Neurol Sci 1996; 137: 109-116
6. Ishikawa M, Namiki J, Takase M, et al. Effect of repetitive stimulation on lateral spreads and F-waves in hemifacial spasm. J Neurol Sci 1996; 142: 99-106
7. Ishikawa M, Ohira T, Namiki J, et al. Electrophysiological investigation of hemifacial spasm after microvascular decompression: F waves of the facial muscles, blink reflexes, and abnormal muscle responses. J Neurosurg 1997; 86: 654-661
8. Moeller AR, Jannetta PJ. Blink reflex in patients with hemifacial spasm: Observation during microvascular decompression. J Neurol Sci 1986: 72: 171-182
9. Valls-Sole J, Tolosa ES. Blink reflex excitability cycle in hemifacial spasm. Neurology 1989; 39: 1061-1066
10. Kojima A, Ohira T, Takase M, et al. Long-latency response to transcranial magnetic stimulation in patients with hemifacial spasm. Electroencephalogr Clin Neurophysiol 1998; 109: 285-289
11. Ishikawa M, Namiki J, Takase M, et al. F-waves of the facial muscles in healthy control subjects and in patients with peripheral facial nerve disturbance. Electromyogr Clin Neurophysiol 1999; 39: 167-174
12. Kimura J. The blink reflex as a clinical test. In: Aminoff MJ, ed. Electrodiagnosis in Clinical Neurology, 3rd edn, New York: Churchill Livingstone, 1992: pp. 369-402
13. Moeller AR, Jannetta PJ. On the origin of synkinesis in hemifacial spasm: Result of intracranial recordings. J Neurosurg 1984; 34: 569-576
14. Moeller AR, Jannetta PJ. Monitoring facial EMG responses during microvascular decompression operations for hemifacial spasm. J Neurosurg 1987; 66: 681-685
15. Montero J, Junyent J, Calopa M, et al. Electrophysiological study of ephaptic axono-axonal responses in hemifacial spasm. Muscle Nerve 2007; 35: 184-188
16. Tamura K, Nishimura T, Mori K, et al. Abnormal evoked EMG and blink refles responses in patients with hemifacial spasm. Brain Nerve 1994; 46: 479-485
17. Ishikawa M, Takase M, Namiki J, et al. Silent period in the mentalis muscle induced by facial nerve and cutaneous stimulation. J Clin Neurophysiol 2001; 18: 386-392