Evacuated calcium phosphate spherical microcarriers for bone regeneration

Tissue Engineering - Part A

Volumn 16, Issue 5, 2010, Pages 1681-1691

  Park, Jeong Soo ^a,b   Hong, Seok Jung ^a,b   Kim, Hee Young ^a   Yu, Hye Sun ^a,b   Lee, Young Il ^a,b   Kim, Chul Hwan ^a,c   Kwak, Sahng June ^a,b   Jang, Jun Hyeog ^d   Hyun, Jung Keun ^a,b   Kim, Hae Won ^a,b,c  

^a BK21 Plus NBM Global Research Center for Regenerative Medicine   (South Korea)

^b Dankook University   (South Korea)

^c Dankook University   (South Korea)

^d Inha University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BONE; CALCIUM; CALCIUM PHOSPHATE; CELL CULTURE; CELL PROLIFERATION; EMULSIFICATION; MICROSPHERES; OSTEOBLASTS; PHOSPHATES; SPHERES; THREE DIMENSIONAL; TISSUE ENGINEERING; TWO DIMENSIONAL;

BIOACTIVE CALCIUM PHOSPHATES; BONE DEFECT; BONE FORMATION; BONE REGENERATION; BONE TISSUE ENGINEERING; CELL POPULATIONS; CELL SEEDING; CULTURE DISHES; HUMAN ADIPOSE; MATRIX; MICRO-PARTICLES; MICROCARRIERS; MICROPARTICULATES; OSTEOGENIC; RAT BONE MARROW; SOLVENT EVAPORATION; SPHERICAL PARTICLE; SPHERICAL SUBSTRATES; THREE-DIMENSIONAL (3D);

STEM CELLS;

ORYCTOLAGUS CUNICULUS; RATTUS;

CALCIUM PHOSPHATE; DRUG CARRIER; MICROSPHERE;

ADIPOSE TISSUE; ANIMAL; ARTICLE; BONE DEVELOPMENT; BONE REGENERATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SHAPE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; FEASIBILITY STUDY; HUMAN; PATHOLOGY; PILOT STUDY; RABBIT; RAT; SKULL; STEM CELL; TISSUE ENGINEERING; ULTRASTRUCTURE; X RAY DIFFRACTION;

ADIPOSE TISSUE; ANIMALS; BONE REGENERATION; CALCIUM PHOSPHATES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SHAPE; DRUG CARRIERS; FEASIBILITY STUDIES; HUMANS; MICROSPHERES; OSTEOGENESIS; PILOT PROJECTS; RABBITS; RATS; SKULL; STEM CELLS; TISSUE ENGINEERING; X-RAY DIFFRACTION;

EID: 77953821083     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2009.0624     Document Type: Article

References (28)

1. Despoina, M.Ch., Helen, D., and Maria, K. Stem cells: promises versus limitations. Tissue Eng 14, 53, 2008.
2. Langer, R., and Vacanti, J.P. Tissue Engineering. Science 260, 920, 1993.
3. Pachence, J.M., and Kohn, J. Biodegradable polymers for tissue engineering. In: Lanza, R.P., Langer, R., and Chick, W.L. eds. Principles of Tissue Engineering. Austin, Texas: Landes Co, R.G., 1997, p 273.
4. Bajpai, P.K. Biodegradable scaffolds in orthopedic, oral and maxillofacial surgery. In: Rubin, L.R. ed. Biomaterials in Reconstructive Surgery. St. Louis, MO: CV Mosby, 1983, p 156.
5. Damien, C.J., and Parsons, J.R. Bone graft and bone graft substitutes: a review of current technology and applications. J Appl Biomater 2, 187, 1991.
6. Hollinger, J.O., and Chaudhari, A. Bone regeneration materials for the mandibular and craniofacial complex. Cells Mater 2, 143, 1992.
7. Patrick, B., O'Donnell, P.B., James, W., and McGinity, J.W. Preparation of microspheres by the solvent evaporation technique. Adv Drug Delivery Rev 28, 25, 1997.
8. Okada, H., Yamomoto, M., Heya, T., Inoue, Y., Kamei, S., Ogawa, Y., and Toguchi, H. Drug delivery using biodegradable microspheres. J Control Release 28, 121, 1994.
9. Al Ruhaimi, K. Bone graft substitutes: a comparative qualitative histologic review of current osteoconductive grafting materials. Int J Oral Maxillofac Implants 16, 105, 2000.
10. Malda, J., and Frondoza, C.G. Microcarriers in the engineering of cartilage and bone. Trend Biotechnol 24, 299, 2006.
11. Kim, H.W., Gu, H.J., and Lee, H.H. Microspheres of collagen-apatite nanocomposites with osteogenic potential for tissue engineering. Tissue Eng 13, 956, 2007.
12. Hong, S.J., Yu, H.S., and Kim, H.W. Tissue engineering polymeric microcarriers with macroporous morphology and bone-bioactive surface. Macromol Biosci 9, 639, 2009.
13. Yoon, B.H., Kim, H.E., and Kim, H.W. Bioactive micro-spheres produced from gelatin-siloxane hybrids for bone regeneration. J Mater Sci Mater Med 29, 2287, 2008.
14. Kim, T.K., Yoon, J.J., Lee, D.S., and Park, T.G. Gas foamed open porous biodegradable polymeric microspheres. Bio-materials 27, 152, 2006.
15. Qiu, Q.Q., Ducheyne, P., and Ayyaswamy, P.S. New bio-active, degradable composite microspheres as tissue engineering substrates. J Biomed Mater Res 52, 66, 2000.
16. Korbling, M., and Estrov, Z. Adult stem cells for tissue repair\a new therapeutic concept? N Engl J Med 349, 570, 2003.
17. Pittenger, M.F., Mackay, A.M., Beck, S.C., Jaiswal, R.K., Douglas, R., and Mosca, J.D., Moorman, M.A., Simonetti, D.W., Craig, S., and Marshak, D.R. Multilineage potential of adult human mesenchymal stem cells. Science 284, 143, 1999.
18. Connolly, J.F. Clinical use of marrow osteoprogenitor cells to stimulate osteogenesis. Clin Orthop Relat Res 355, 257, 1998.
19. Zuk, P.A., Zhu, M., Ashjian, P., De Ugarte, D.A., Huang, J.I., and Mizuno, H., Alfonso, Z.C., Fraser, J.K., Benhaim, P., and Hedrick, M.H. Human adipose tissue is a source of multi-potent stem cells. Mol Biol Cell 13, 4279, 2002.
20. Mizuno, B.M., and Hedrick, M.H. The growing importance of fat in regenerative medicine. Trends Biotechnol 23, 64, 2005.
21. Daculsi, G. Biphasic calcium phosphate concept applied to artificial bone, implant coating and injectable bone substitute. Biomaterials 19, 1473, 1998.
22. Kim, H.W., Knowles, J.C., and Kim, H.E. Effect of biphasic calcium phosphates on drug release and biological and mechanical properties of poly(e-caprolactone) composite membranes. J Biomed Mater Res A 70A, 467, 2004.
23. Lee, H.H., Hong, S.J., Kim, C.H., Kim, E.C., Jang, J.H., Shin, H.I., and Kim, H.W. Preparation of hydroxyapatite spheres with an internal cavity as a scaffold for hard tissue regeneration. J Mater Sci Mater Med 19, 3029, 2008.
24. Yu, H.S., Hong, S.J., and Kim, H.W. Surface-mineralized polymeric nanofiber for the population and osteogenic stimulation of rat bone-marrow stromal cells. Mater Chem Phys 113, 873, 2009.
25. Zuk, P.A., Zhu, M., Mizuno, H., Huang, J., Futrell, J.W., Katz, A.J., Benhaim, P., Lorenz, H.P., and Hedrick, M.H. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng 7, 211, 2001.
26. Kim, W.S., Park, B.S., Sung, J.H., Yang, J.M., Park, S.B., Kwak, S.J., and Park, J.S. Wound healing effect of adipose-derived stem cells: a critical role of secretory factors on human dermal fibroblasts. J Dermatol Sci 48, 15, 2007.
27. Park, J.S., Kim, H.Y., Kim, H.W., Chae, G.N., Oh, H.T., and Park, J.Y., Shim, H., Seo, M., Shin, E.Y., Kim, E.G., Park, S.C., and Kwak, S.J. Increased caveolin-1, a cause for the declined adipogenic potential of senescent human mesenchymal stem cells. Mech Ageing Dev 126, 551, 2005.
28. Kong, Y.M., Kim, H.E., and Kim, H.W. Phase conversion of tricalcium phosphate into Ca-deficient apatite during sintering of hydroxyapatite- tricalcium phosphate biphasic ceramics. J Biomed Mater Res B 84B, 334, 2008.